feel really bad. It seems to be my stomach/GI tract that gets most effected. It's only been a week of t4 100mcg/t3 10mcg. Was on 112 t4 and 5 t3. The last time I went down to t4 100 I had the same stomach problems, it's painful like being completely dehydrated with complete shut down of my GI tract. I have pains in my lower and upper back and feel awful.
So, I have increased today to 125mcg and T3 7.5.
I felt sl better on t4 125mcg but then my t4 was 25 (range up to 22). My TSH is always suppressed and i had hoped going to t4 100 would have raised it, but it really makes me ill going to that level, mainly due to the stomach issues/back pain and dehydration feeling - like a bad hangover.
The last time I tried to go to t4 100, was last Oct and my GI tract , more of less, shut down. My stomach, intestines were rock hard and I actually thought I had a growth under my ribs. I also had sl diarrhea, and hence did not realise I was 'constipated'. I took a lot of prunes, 5 days after getting the 'hard' intestines, and that reversed it and I then realised my GI function had practically stopped. I also got extreme anxiety, what felt like a stomach ulcer, for several mths after, also flu like symptoms, lower back pain, etc.. so believe I wrecked my gut flora at this time.
I am doing a SIBO breath test this week.
However, as this stomach problem has reoccurred, by lowering to t4 100 that's the end of that plan of thinking to get my TSH to rise! I believe the increased t3, ensured it was not as bad as the first attempt when i was on t4 100 and 5 t3.
The worst of it is, I had sweet spots when I first lowered my T4, in 2016, ,and felt 'normal' for the first time in ages, but that has since gone. I had been on 150/175 (winter mths) for 30 yrs prior to my results going out of range.
I would stay at the 125 and forget about it, except my hair falls out each time I stay on 125, hence why I reduced to 112mcg, however I think I felt better on 125.
I will try 112 plus t3 7.5 for a while and see how it goes. Possibly a few days of 125 first.
I also feel an immediate effect when increasing/lowering my dose of thyroxine 'even though' it has a long shelf life (within an hour)!