Best time of day to have FT3 test ?: Dear All... - Thyroid UK

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Best time of day to have FT3 test ?

Milpol profile image
11 Replies

Dear All,

Happy New Year!

Please could anyone advise on the above question. I think your T3 level drops mid afternoon, so would this be the best time for testing to get the lowest reading?

Many thanks x

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Milpol profile image
Milpol
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11 Replies
jimh111 profile image
jimh111

Assuming you are not taking thyroid hormone fT3 varies by about 6% during the day. Not worth the bother. I assume this would also hold for someone taking levothyroxine only.

humanbean profile image
humanbean

Graphs of the variation in TSH, Free T4 and Free T3 over 24 hours can be found on page 2 of this paper :

reboundhealth.com/cms/image...

jimh111 profile image
jimh111 in reply tohumanbean

Note the values for the fT3 graph, about 5.2 to 5.6. The graph is a bit misleading at first glance because they have zoomed in, not shown the origin. I have seen a paper which showed the TSH diurnal variation is preserved for patients on levothyroxine. Can't remember the paper but I'd be surprised if anyone was that keen to see it.

Milpol profile image
Milpol in reply tojimh111

Many thanks jimh111.

Milpol profile image
Milpol in reply tohumanbean

Many thanks humanbean x

silverfox7 profile image
silverfox7

I think consistency is important and as I take my basal temperature anyway then that's the one I record. It doesn't appear to make a huge change whenever you take T3. I wastold go take it first thing but check temperature first thing then about 3 pm and work towards 36.9 in the morning and 37.0 in the afternoon and taking NDT I now take it all at once in the morning as often missed the second as I forgot about it! So back to the consistency point again.

Milpol profile image
Milpol in reply tosilverfox7

Thanks silverfox7. Information much appreciated x

You really need TSH, free T4 and free T3 done together so you can see if they are "in balance"

Milpol profile image
Milpol in reply toAngel_of_the_North

Many thanks Angel-of-the-North.

So would that be first thing on a morning on an empty stomach or not necessary?... same as for TSH ? Sorry, still learning about all this 🙄

Angel_of_the_North profile image
Angel_of_the_North in reply toMilpol

I would tend to do it that way so I could compare all my tests.

Milpol profile image
Milpol in reply toAngel_of_the_North

Thank you ☺️

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