RT3 but normal other thoroid values

[Zsolt]

Dear Community,

Can someone shed some light on high rt3 level?

Tried to dig up info on it, and all i found is that rt3 protects thoroid from high T3, so it block the receptors without actually activating them.

I have high rt3 but normal T3, so i don't understand. -> attaching my results

Regards,

Zsolt

[greygoose]

Well, that's sort of right. But not quite. RT3 is high in people with some sort of illness - flu or something - or people who are starving, in order to reduce T3 and thereby conserve energy.

It used to be thought that rT3 blocked T3 receptors, but it is now known that that isn't true, the rT3 has it's own receptors.

But, rT3 can be high for other reasons, for example, if you are a poor converter and have too much unconverted FT4 in your system, the excess T4 is converted to rT3 to avoid wasting the T4, because rT3 goes on to be converted to T2. Your FT4 isn't excessively high, but then, neither is your rT3.

I don't really think you have a conversion problem, so how is your iron? Low iron can cause high rT3, as well as low/high cortisol.

[Zsolt in reply to greygoose]

wow thanks, that is informative!

I have long history of strange symptoms, low grade fever, itching, brain fog, poor concentration, intolerance to almost every food, constipation, candida, bad sleeping.

And i was an organized engineer, and was practicing kung-fu 5 years ago. But 4 years ago something started to broke in me, and getting worst and worst.

Doctors have no clue..

I was planning to do extra texts for Epstein barr - your answer just made me more determined i need to do that.

+will do full mineral test as well.

Can you think of anything else, to test?

IMHO i have adrenal fatigue too, but does it make sense to do a cortisol daily profile to confirm that?

[greygoose in reply to Zsolt]

Just had a peep at your last post, and you got some very good suggestions of things to test for, on that. Have you don't all those tests? Especially those suggested by denvajade.

If you feel unwell, it always makes sense to check your cortisol. Are you thinking of a 24 hour saliva test? That's the best one to do.

Have you done liver tests?

[Zsolt in reply to greygoose]

Yes i have done probio profile, candida, fat digestion.

Food intolerance for 250 thing.

The things that are proven for me:

1. Biliary dyskenisia

2. Extreme low bifido level (lacto are ok, and no other pathogenic oovergrowth)

3. I have oral candidiasis (it is quite strange because in stool its negative)

4. High histamine in stool

D vitamin is normal

Will do b12, ferritin, iron, na, magnesium, ca,ka

Current therapy:

1. Eat very simple things, no sugar at all, small fruti, vegetable, rice and meat

I dont eat any allergetic type of food, 0% gluten, 0% diary, 0% egg, 0%corn, 0% soy, 0% nuts

2. Probiotic (tried different types)

3. Lot of water

4. curcumin for candida&biliary dyskenisia

Doing this since 12 months.

Made some progress, but only around 40%. So for example i used to have each day 37.8 low grade fever now i have 37.3.

Recovered some energy, but still much to improve.

@@There is still something missing, some underlying thing that is not treated

+Liver test showed elevated bilirubin with 5%

Not sure what to check there additionally?

[greygoose in reply to Zsolt]

I'm afraid I can't help you much further than that. But, it is very important to get your ferritin, B12 etc. tested.

Not much point in testing for magnesium because it will always be in-range, due to the way the body handles magnesium. But, that doesn't mean that you aren't deficient. Most people are, because levels are depleted in the soil.

[Zsolt in reply to greygoose]

thanks for all the help!

I really appreciate that!

[greygoose in reply to Zsolt]

You're more than welcome.

[Zsolt in reply to greygoose]

If i may ask 1 more thing B12 and folate test just came out.

B12 170,0 pmol/L 133,0 - 675,0

Folate 14,8 nmol/L 8,1 - 45,3

B12 deficiency is evident, what do you think folate too?

And would you recommend b complex or b12+folate only?

Additionally would you recommend b12 shots(as injection) or normal oral tablets?

[greygoose in reply to Zsolt]

Yes, your B12 is very low, and with such a low B12, I think you ought to ask your doctor to test you for Pernicious Anemia.

If you have PA, you will get NHS B12 shoots for life - or you should do, if you're in the UK. But, otherwise, it's difficult to get doctors to give you shots, so you'll have to take tablets.

And, if you're taking either tablets, or shots, you should take a B complex to keep the Bs balanced. If you get one with at least 400 mcg methylfolate, that will bring your folate up nicely - because it is a bit low - should be at least mid-range. And, that would be better than folic acid tablets.

[Kell-E]

Here is a link to an article by Kent Holtorf, an advisor to Thyroid UK.

He definitely feels that rT3 is important.

holtorfmed.com/download/thy...

Thus, rT3 is an excellent marker for identifying

reduced cellular T4 and T3 levels that would not

normally be detected by TSH or serum T4 and

T3 tests. As a result, any increase (high or highnormal)

of rT3 is not only an indicator of tissue

hypothyroidism but also suggests that T4-only

replacement would not be considered optimal

therapy.