As my prescription t3 is still under threat I've been experimenting with Levothyroxine (yuk) only but now have some definitive experience that I'd like to be able to explain authoratively to the powers that be, so they don't just tell me to increase the Levothyroxine dose if I am still hypo. Can anyone explain the following mechanism to me?
I have absolutely found a maximum amount of thyroxine that I can tolerate before it gives me insomnia as well as very light unrefeshing sleep, where I wake up feeling dreadful. It's a tiny amount of Levothyroxine where I've had to resort to cutting 50mcg T4 pills up to get-50mcg and 37.5mcg alternate days. Even increasing to 50/50 brings on the insomnia. However, although 50/37.5 gives me lovely quality sleep it leaves me with lots of physical hypo symptoms but so too does any higher dose of Levothyroxine, so I'm better taking the lower dose of Levothyroxine where I sleep great. Poor sleep quality is my biggest day to day symptom that robs my joy in life when meds aren't at appropriate dose....
So, my question is, does anyone have a name for this phenomenon or know the mechanism where Levothyroxine would be too high to sleep and give me insomnia but leave my body hypo? Is the brain's sleep centre particularly sensitive to t4? Is t4 converted more efficiently in the brain or something like that explains how it can disrupt my sleep but leave me true hypo?
This is the reason I added t3 Liothyronine in the first place to a reduced dose of Levothyroxine, as t3 restores my quality of sleep rather than give me insomnia as most endos would have us believe. I'm really keen to have the scientific explanation as why the Levothyroxine can give me insomnia which could indicate too much t3 but leave me physically hypo (carpel tunnel, constipation etc). Thank you.😊