Move from NDT to T3

[Helena877]

I'm currently on two grains of Nature-Throid and wanting to transition across to T3. ( I finally received my T3 after four weeks waiting).

How should I transition across? I don't have current blood results but can obtain some new ones before starting the T3.

The tablets are from Unipharma 25mcg.

Thank you

[Clutter]

Helena877,

2 grains NDT is equivalent to 50mcg T3. You are taking 18mcg T3 already in 2 grains so you might want to start with 31.25mcg (1 and 1/4 tablets) for a week while the T4 in NDT is washing out and increase to 50mcg a week later. Hold at 50mcg for six to eight weeks and have a FT3 test to check FT3 remains within range.

[Helena877 in reply to Clutter]

Thank you Clutter

Is it down to individuals how best to take their doseage?

I always took my two grains NDT together as found it to be more beneficial this way. Splitting the dose didn't appear to spread out the benefits of the T3 but a big boost in the a.m. benefited me all day.

Would you recommend I space T3 out or is one dose okay?

[Clutter in reply to Helena877]

Helena877,

It is physiologically better to even out the T3 peaks by splitting into 2 or 3 doses. See the graph in tiredthyroid.com/blog/2015/...

I recommend you split T3 into 2 doses until you know how you do on the increased dose.

[shaws in reply to Helena877]

I take my T3 in one dose and followed Dr Lowe who was an expert in T3. He was also an Advisor to Thyroiduk.org.uk and ran DrLowe.com, Fibromyalgia Research Foundation and Thyroidscence before his untimely death.

I shall give you a link and you can decide which you prefer. Extract from date January 30, 2002. (I have no idea why ' has changed into question marks in a triangle)

"I�m a physician who has just begun using T3 in my practice. One thing I�m concerned about is the short half-life of T3. Shouldn�t patients divide their daily dose up and take part of it at least twice each day, or instead use sustained-release T3? It seems that this would allow the effects of T3 to continue through the day rather than stop midway or in the evening?"

part answer:

The short time that T3 is in the circulating blood isn�t the limit of its beneficial effects on the body.........................

Moreover, the newly synthesized proteins themselves far outlast the transcription and translation. As a result, a single dose of T3 will be long gone from the patient's system before he or she experiences most of the benefits of that dose�a molecular and metabolic yield that may smoothly spread out over one to three days. The "rocky road" ( August 7, 2001)

web.archive.org/web/2010103...

Dr L took one daily dose of 150mcg of T3 himself (in the middle of the night). He had thyroid hormone resistance.

[greygoose in reply to Helena877]

I take 62.5 mcg T3, and I take it all in one go at night. I don't have any problems with peaks and slumps. Taking it in one dose is fine for me, but we're all different. Maybe you should try different ways to see which way works for you.