The Hertoghe doctors say you need to take DHEA with hydrocortisone or Medrol (unless you also suffer from PCOS). The reason is that DHEA will prevent cortisone from "eating up" too much tissue. Therefore, you are handed a prescription for DHEA along with your prescription for cortisone. Last year, my DHEA-S levels were out of range (372 ug/dL; ref 56-283). Just for comparison: DHEA-S before taking supplements: 152, so not really low.
I have since weaned off both Medrol and DHEA, but this has made me wonder. I have been reading a lot about the benefits and side effects of DHEA, and it seems excess DHEA can have quite serious side effects. This in turn makes me wonder if it's a good sign that a so called hormone specialist renews your prescription for DHEA, even though your levels are out of range (and I always go to the lab 24 h after taking hormones)? Is DHEA really that important in case of cortisone supplementation; if that was indeed the case, should not all patients taking cortisone (including those taking much larger doses for rheumatoid arthritis, for instance) be taking DHEA? However, I've never heard of anyone else taking DHEA along with HC/Medrol.
Recently, I have begun wondering if it's worth it...paying a fortune in doctor's fees, labs and drugs not covered by health insurance, if you are not even sure your doctor knows what s/he is doing...after all, it does seem rather irresponsible to me to prescribe hormones to a patient with out-of-range levels...?