Gone hyper?: Is it possible for levothyroxine to... - Thyroid UK

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Gone hyper?

irme profile image
irme
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Is it possible for levothyroxine to trigger hyperthyroidism? I started feeling very hyper the 6th day I was on tirosint .It's one month since I was taken off the medication I still can't find peace of mind. I have been diagnosed with Hashimoto's but maybe I should test for Graves antibodies? . TSH has dropped but I feel horrible.Is it possible to have both hypo and hyperthyroidism?

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irme profile image
irme
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dang profile image
dang

Not exactly, it's more like being over or under-medicated, or possibly you don't react well to T4 or some fillers in that brand. But since you have Hashimoto's you are hypo, your medication doesn't change that, the "hypo" comes from your thyroid's ability, and as long as your thyroid itself is itself underproducing you are considered hypo, in fact taking meds could make your thyroid produce even less, therefore making you more hypo.

Consider that the problem is the medication itself. For example I have a hard time with t4, when my TSH is in range on t4 I feel horrible, and tests showed that my FT4 is over range, so I have to take T3 medication as well since Levo alone causes me problems.

irme profile image
irme in reply to dang

Thank you

greygoose profile image
greygoose

When you have Hashi's, you can have 'hyper' swings, where the dying cells dump all their hormone into the blood stream in one go, causing levels to run high. But, it's only temporary, you go back to being hypo when all that extra hormone is used up. It has nothing to do with your levo. :)

irme profile image
irme in reply to greygoose

Now it makes sense,thanks!

greygoose profile image
greygoose in reply to irme

You're welcome. :)

Laundretta profile image
Laundretta in reply to greygoose

Hi greygoose, how long do these swings last? I think I had one last week. Initially I thought I’d perhaps overdone my self-imposed t4 increase, of which I’m on week 3, but the overmedicated feelings came on very suddenly and lasted about 18 hours. Now I’m ok again. It was horrible, would never want to be hyper! What do you think?

greygoose profile image
greygoose in reply to Laundretta

Usually several weeks. I very much doubt if a 'hyper' swing would last just 18 hours. The half-life of T4 is about 1 week, so it would take one week for the T4 in your system to reduce by half. And, the more there is of it, the longer it takes. But, it does vary, so can't say exactly how long one would last. :)

Laundretta profile image
Laundretta in reply to greygoose

Hmmmm

That makes total sense. Odd then.

greygoose profile image
greygoose in reply to Laundretta

These things happen. :)

eve196 profile image
eve196 in reply to Laundretta

Hello! This post is quite old. Since then I have been getting a series of misdiagnoses like Lupus,Lyme disease,subacute thyroiditis,MS,ME etc.. Until my eye doctor sent me for an MRI scan which revealed a tumor in my pituitary gland which is secreting extra hormones and messes up my endocrine glands which of course explains all the weird things I have been experiencing the past 30 years.

I seem to have trouble logging in as usual so I am posting this from a new account.

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