Most commonly associated autoimmune diseases - Thyroid UK

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Most commonly associated autoimmune diseases

hose1975 profile image
6 Replies

I've read a lot on this board and the Pernicious Anaemia Society's one that autoimmune diseases often hunt in packs. So I wondered: which of the little buggers are most commonly associated with preexisting autoimmune hypothyroidism? Has any research been done on this that we know of?

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hose1975
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Clutter profile image
Clutter

Hose1975,

I expect there is research on multiple autoimmune diseases but I don't have any to share. Hashimoto's and/or pernicious anaemia and/or Sjogrens are commonly reported on the forum.

Helena877 profile image
Helena877

I have seen a list. Off the top of my head - psoriasis, vitiligo, lupus, type 1 diabetes (late onset) associated with Hashimoto's .

hose1975 profile image
hose1975

Thanks, both.

Pastille profile image
Pastille in reply to hose1975

Rheumatoid arthritis is another. I had vitiligo myself and it's completely cleared up since being properly medicated for thyroid and taking supplements. I think B12 had quite a bit to do with it

I have psoriasis and mild vitiligo on my lower arms and I'm hypo. I also have Raynauds.

helvella profile image
helvellaAdministratorThyroid UK

An association between the occurrence of maternal antithyroid antibodies and recurrent abortion has been reported (399) and although this association has been disputed, a recent study showed clear evidence that the presence of TPO antibodies was associated with a 3-4-fold increased risk of miscarriage in women having in vitro fertilization (400). There is also an association between breast cancer and thyroid autoimmunity (401, 402) and between depression in middle-aged women and the presence of TPO antibodies (403). The nature of these associations is unclear; does thyroid autoimmunity predispose to such adverse events, or is the presence of thyroid autoimmunity simply a marker of a non-specific disturbance in the immune system due to whatever has caused miscarriage, cancer or depression? Having thyroid autoimmunity is not all bad news. Community-dwelling older women who have TG and TPO antibodies are less likely to be frail than those who are antibody-negative (404). Again the reason for this unexpected finding is unclear but it certainly warrants follow-up.

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