Most commonly associated autoimmune diseases

[hose1975]

I've read a lot on this board and the Pernicious Anaemia Society's one that autoimmune diseases often hunt in packs. So I wondered: which of the little buggers are most commonly associated with preexisting autoimmune hypothyroidism? Has any research been done on this that we know of?

[Clutter]

Hose1975,

I expect there is research on multiple autoimmune diseases but I don't have any to share. Hashimoto's and/or pernicious anaemia and/or Sjogrens are commonly reported on the forum.

[Helena877]

I have seen a list. Off the top of my head - psoriasis, vitiligo, lupus, type 1 diabetes (late onset) associated with Hashimoto's .

[hose1975]

Thanks, both.

[Pastille in reply to hose1975]

Rheumatoid arthritis is another. I had vitiligo myself and it's completely cleared up since being properly medicated for thyroid and taking supplements. I think B12 had quite a bit to do with it

[Hidden]

I have psoriasis and mild vitiligo on my lower arms and I'm hypo. I also have Raynauds.

[helvella Administrator]

An association between the occurrence of maternal antithyroid antibodies and recurrent abortion has been reported (399) and although this association has been disputed, a recent study showed clear evidence that the presence of TPO antibodies was associated with a 3-4-fold increased risk of miscarriage in women having in vitro fertilization (400). There is also an association between breast cancer and thyroid autoimmunity (401, 402) and between depression in middle-aged women and the presence of TPO antibodies (403). The nature of these associations is unclear; does thyroid autoimmunity predispose to such adverse events, or is the presence of thyroid autoimmunity simply a marker of a non-specific disturbance in the immune system due to whatever has caused miscarriage, cancer or depression? Having thyroid autoimmunity is not all bad news. Community-dwelling older women who have TG and TPO antibodies are less likely to be frail than those who are antibody-negative (404). Again the reason for this unexpected finding is unclear but it certainly warrants follow-up.

thyroidmanager.org/chapter/...