I've switched from 100mg to 500mg of adrenal cortex supplements such as Adrenavive III but it seems to bring on feelings of depression/sadness which clears up 3-4 hours later after each dose. I take 250mg with breakfast and another 250mg with lunch. My body temperature increases after I have took them. My lips sometimes quiver slightly and I feel a little jittery inside. I've only been at this dose for 1 week. Just wondering if anyone else has felt like this from taking adrenal supplements or HC?