My doctor increased my dosage of .50mcg levothyroxine to .75mcg 5 weeks ago. I have been losing quite a bit more hair than usual. I'm wondering if this can be the cause. I've also been taking 2 tabs / day of tramadol for a few years. I also started evening primrose at same time I increased the levothyroxine. So,I don't know which it could be. Seems from what I've been reading it could be both the tramadol and/or levothyroxine. But I've been on levothyroxine for 20 years with not a lot of hair loss.