Thyroid UK
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Low Oxygen might be the Root Cause of all my Endocrine Issues

Hi everyone,

I'm still in my journey to discover the root of my health issues. I notice my oxygen level always around 94% compared to normal people with 98%-99%.

I found in my recent research, low oxygen may trigger an intense adrenal response (high cortisol) which affect thyroid production and conversion.

What are the possible causes of low oxygen?



11 Replies

Low Iron maybe ? Oxygen adheres to iron in the red blood cells for transportation onwards...... just a thought.

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Thanks Marz, I had a normal iron and ferritin levels.


'Normal' is just an opinion. Do you have the exact numbers?

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Anaemia (low haemoglobin) won't effect oxygen saturation as pulse oximetry reflects the percentage of oxygen attached to the haemoglobin. Therefore if your haemoglobin is low but it is carrying the maximum amount of oxygen the oxygen saturation will be high (greater than 96%), but you may still be hypoxic (short of oxygen) as you don't have enough carrying capacity due to anaemia. Low oxygen saturation is primarily a problem within the lungs. Something is preventing the oxygen crossing the alveolar membrane to attach to the haemoglobin, there are many causes of this from infection, damage from COPD, recording saturations just after smoking a cigarette. It can also be a circulation problem in that blood doesn't perfuse the part of the lung with the oxygen, this can be what happens with pulmonary embolis, as the clot stops blood flow to part of the lung.

In order to investigate further you need to consider if you become breathless on exertion. Has your exercise tolerance declined over the last year? If it has it would be sensible to ask your GP for further investigations.

I wish you well.


Are you sure your levels of iron were normal? In normal range often doesn't mean optimal.


Ali1 101

"I found in my recent research, low oxygen may trigger an intense adrenal response (high cortisol) which affect thyroid production and conversion."

Do you have a link to this research please?

I have COPD, my oxygen level is always 94/95%, I have low adrenal reserve with high in range cortisol and low DHEA and apparent poor conversion of T4 to T3 shown in both blood and urine tests.

It would be interesting to see if this is all linked.

And I agree with cjrsquared that you should ask about lung function tests with an oxygen level of 94%.

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I came to the above conclusion by reading several sources, some:


Unfortunately the first link is too scientific and too lengthy for me, my hypo brain isn't capable of making any sense of the amount that I am able to read. In the second link I can't see anything to do with low oxygen levels, but like I say my brain can't cope with wordy scientific stuff.


The first link didn't point to the right place anyway! but all they say is when you have low oxygen, the adrenal will work harder as a response to hypoxia. The second link is about poor conversion of T4 to T3 when you have high cortisol.


Mastocytosis was one if I remember it correctly. Have been reading about it this weekend and remember running into lower oxygen.


chlorine and fluoride both attack oxygen in the body also carbon monoxide is bad, when the british government started the insulating the houses project monoxide deaths increased a huge amount.

a few plants you might want to have inside are aloe vera, cactus and mothers tongue all give out oxygen at night where as most plants take in oxygen at night,

you could also get a cool mist humidifier and use a bottle of 3% food grade hydrogen peroxide every night this would create a hyperbaric oxygen chamber in your room and you will certainly get a better nights sleep

also to replenish your blood supplies of haemoglobin find a beekeeper who can sell you some Propolis, this has increased blood by 25% over 8 weeks in some people.

do not buy this in a shop as the legal level is only 1 ppm and you do not know what you are getting.

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