What are high THYROTROPHIN receptors a symptom... - Thyroid UK

Thyroid UK

137,936 members161,765 posts

What are high THYROTROPHIN receptors a symptom of? is it Hashimotos?

Silverlady5 profile image
5 Replies

i posted all my results on Friday and humanbean very kindly replied but has anyone else got any thoughts on this please?

My b12 is looking a bit low too so I know I need to supplement to raise those levels can re submit my levels if you haven't seen them

Thanks to everyone your support means a lot x

Written by
Silverlady5 profile image
Silverlady5
To view profiles and participate in discussions please or .
Read more about...
5 Replies
helvella profile image
helvellaAdministratorThyroid UK

Thyrotropin receptor antibodies (also known as TSH-receptor antibodies or TRABs) come in three "flavours" - blocking, stimulating and "don't have much effect".

Stimulating TRABs are the cause of hyperthyroidism in Graves disease.

Blocking and "don't have much effect" TRABs often have little effect but blocking TRABs can impact on thyroid output.

The most common TRAB tests do not distinguish among the three flavours - that is very often done by checking out the clinical picture.

Silverlady5 profile image
Silverlady5 in reply to helvella

Thank you helvella I am feeling so confused by this to be honest.

I am hypothyroid after RAI and didn't realise you could still have Graves' disease which I had when I was hyper.

Humanbean sent me various info but don't think I'm taking things in very well with how I'm feeling

helvella profile image
helvellaAdministratorThyroid UK in reply to Silverlady5

Unfortunately Graves disease does not get cured by thyroidectomy - it is just that the stimulating TRABs having nothing to stimulate. So you do not produce thyroid hormone and so don't become (or stay) hyperthyroid.

I do not know what impact high stimulating TRABs have in someone without a thyroid.

Silverlady5 profile image
Silverlady5

I haven't had a thyroidectomy had a partial thyroidectomy when I was 21 im now 63.

My remaining thyroid was controlled without medication for many years then became over active on off and I was on carbimazole but told by endo that RAI was the answer.

I'm not sure I know what the answers are any more I become more and more confused awith every passing day

Clutter profile image
Clutter in reply to Silverlady5

Silverlady5, the RAI will have destroyed your remaining thyroid and made you hypothyroid.

You may also like...

Possible Hashimoto's but no symptoms?

my thyroid levels are low. He was completely flummoxed by the fact that my blood test results show...

Hashimoto's & high blood pressure

Hi everyone, I wonder if anyone out there has Hashimoto's and high blood pressure. I recently had...

High cholesterol Hashimotos

My recent cholesterol result was 7.7 which is up from December last year when it was 6.7. My Endo...

High Antibodies - Hashimotos

I will be visiting my GP soon with blood test results that I had done privately.  My Antibodies,...

Hashimotos and high heart rate

have high anti tpo (~500), TSH ft3, ft4, everything else is normal, but my resting heart rate is...