Starting T3 tomorrow, best times of day to take it?

So I finally got my hands on some liothyronine, and now I'm feeling a bit anxious about starting it - sounds silly but I guess I'm just not sure what to expect.

I need to take 20mcg split into two doses and I just wondered what times I should take it at. I normally take my levo at 7, so I thought maybe 7 and 3 - does that sound ok?

Bought a pill cutter - the first one crumbled so not a great start!

Many thanks for any advice


18 Replies

  • You might find a craft knife/hobby knife/scalpel with replaceable blades better for cutting than a pill cutter. They can easily be found for less than a fiver on Amazon.

  • Thank you, might try that

  • Are your tablets scored? Mine crumbled a few times too!!!! I started taking mine morning 6/7 am and then bed time, then I changed my bedtime one to 3 pm as I was experiencing a 3 pm brick wall, but after a few weeks I took it all at once in the morning x

  • They are, maybe the first one was just bad luck! That's good to know, once would be easier!

  • I take my T3 once daily (33mcg approx) and am fine. I take it when I get up and have breakfast about 3/4 to 1 hour later. Then I get on with my day without worrying about taking more.

    If you do split your dose - stomach should be empty so around 2 to 2.5 hours should elapse after eating plus approx 1 hour after T3.

  • Thanks Shaws, hope once a day might work for me esp as I'm always hungry mid afternoon!

  • This is an excerpt and link:-

    I want to emphasize, however, that when our protocol is used properly, there is no overstimulation to be avoided by using timed-release T3. The protocol has safeguards against adverse effects.

    And finally, why do I specify that the typical patient use one full dose of non-timed-release Cytomel for life? Because extensive testing has shown that this is safe, effective, and most economical—when used within the context of our entire protocol.

  • Thanks that's helpful

  • Mountaingoat, I take my T3 with my T4 at 7am and then later in the day at 4pm. This seems to work for me. I bought a brilliant pill-cutter from Kleeneze for £2.99. It is better than one I got from the pharmacy.

  • Thanks for the tips

  • Dr Lowe, a pioneer on the use of t3, took his all at once at bedtime, others take it all at once in the morning, empty stomach, away from supps. The key, according to him, was all at one time, to saturate the cells.

  • Thank you, I think I'll try that once I'm used to it

  • Begin gradually but I found (levothyroxine gave me awful palpitations) T3 calmed my whole system down and it was such a relief not to have my heart jumping out my chest at any time day or night.

    Wishing you good luck.

    If you've read the link I gave above you will find that Dr Lowe said that (Cynomel I believe (T3) has no side effects.

  • Thank you, I feel like my heart is pounding a bit tonight, but also feel like I might be getting a cold so I'll blame that!

  • there is no getting used to it really, just go up gradually..this "multiple dosing needed", is a myth.

  • Thanks, it really helps to hear other people's experiences

  • Do you know how much Dr. Lowe was taking all at once? For me, T4 only lasts 4-5 hours in my system, I don't understand how he would have prevented depression the next day....I have never had more than 15 mcg at once, so maybe that's why it doesn't last very long?

  • I think he took 120mcg - 150mcg per day. Shaws would know, she has read lots of his stuff.

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