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Hi I was diagnosed almost 20 years ago with hypothyroidism. It was a great feeling of relief at last to put a name to my condition. I am now taking 150 levothyroxine with limited benefit. My quality of life is poor. I have made many complaints about my health over the years I have attended an endocrinologist till recently , who just increased my dose instead of trying to work out why the medication was not eliminating all my symptoms even though I was told by many doctors I was over medicated. I am now 70 years old and being new to computers I had no idea that levothyroxine does not work for all patients. I have attended many clinics at hospital with numerous health complaints over the years. I now feel that the addition of T3 along with levothyroxine may have had a better outcome, or a trial with natural thyroxine. i don't want to waste any more time and i will to ask my doctor to try different remedies .

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  • If you are in the UK, it is difficult to get prescribed some T3 or NDT. Some doctors may add T3 to your levo and it it has been found to be helpful. Some members are forced to buy their own online:

    hormonerestoration.com/

    This is from the Journal of Orthomolecular Medicine and go to Page 80 to read the appropriate para on the l/hand side.

    The various RCTs used T4:T3 ratios of 14:1, 10:1, and 5:1. Subsequent research by the US National Institutes of Health (NIH) found the therapeutic equivalence was 3:1. Thus, most of the subjects were under

    treated with the T3/T4 combination. In light of the NIH finding, the conclusion that T3 therapy is never needed is invalid

    tpauk.com/images/docs/reduc...

    I take T3 only and feel very well now but it doesn't agree with everyone.

  • Jean2245. Levothyroxine doesn't work well for everyone and although the addition of T3 may be helpful, it's also useful to check that ferritin, vitamin D, B12 and folate are optimal. Ask your GP to check. Always request a printout of thyroid and other blood tests with ranges (figures in brackets after results) and post them in a new question for advice.

    You may find your GP is unable to prescribe T3 without a NHS endo recommendation.

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