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Factors affecting Cortisol levels

Factors affecting Cortisol levels

Caffeine may increase cortisol levels.

Sleep deprivation increases cortisol levels.

Intense (high VO2 max) or prolonged physical exercise stimulate cortisol release in order to increase gluconeogenesis and maintain blood glucose. Proper nutrition and high-level conditioning can help stabilize cortisol release.

Val/Val variation of the BDNF gene in men, and the Val/Met variation in women is associated with increased salivary cortisol in a stressful situation.

Magnesium supplementation decreases serum cortisol levels after aerobic exercise, but not in resistance training.

Omega 3 fatty acids, in a dose dependent manner, can lower cortisol release influenced by mental stress by suppressing the synthesis of interleukin-1 and 6 and enhance the synthesis of interleukin-2, where the former promote higher CRH release. Omega 6 fatty acids, on the other hand, acts inversely on interleukin synthesis.


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"Sleep deprivation increases cortisol levels."

That's interesting. When I did the Genova saliva test for adrenal function my cortisol level first thing was sky high (low the rest of the day). This explains it as I was going through a particularly bad bout of insomnia at the time (I still am - but not as bad as it was). I didn't know that sleep deprivation *increased* cortisol levels - it seems somehow counter-intuitive.

Thanks for posting!

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You might find the following of interest:

Wisdom in your treatment of adrenal issues

And check the other articles under 'Adrenal Problem' tab.

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Many thanks. I'll take a good look at all this. :-)


You're welcome, best of luck :-), also The Adrenal/Thyroid connection:


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