Anyone need ammunition for refusing statins whilst hypothyroid?
Eur Thyroid J. 2015 Mar;4(1):62-4. doi: 10.1159/000371548. Epub 2015 Feb 18.
Rhabdomyolysis in the setting of induced hypothyroidism and statin therapy: a case report.
Jbara Y1, Bricker D1.
Mild elevation of creatine kinase (CK) is common in untreated hypothyroidism, but severe myositis and overt rhabdomyolysis are rare. Similarly, muscle pain and CK elevation are potential side effects of statin therapy, yet rhabdomyolysis is likewise rare in the absence of medication interactions adversely affecting statin metabolism. The coexistence of statin therapy and hypothyroid states may synergistically increase the risk of myopathy. We describe a case of rhabdomyolysis attributable to induced hypothyroidism in a patient on chronic statin medication who was anticipating adjuvant radioiodine ((131)I) therapy for a thyroid carcinoma.
Induced hypothyroidism; Recombinant human thyrotropin; Rhabdomyolysis; Statin therapy