Thyroid Eye Disease Research at the U-M Kellogg Eye Center

Published on 20 Apr 2015

Thyroid eye disease specialist, Dr. Raymond Douglas, talks about the thyroid eye disease (Graves' eye disease) research at the Kellogg Eye Center.

Largest clinical trial in USA for a biologic intervention for this disease.

Really exciting news on trying to block the receptors IGF-1 and TSH. Again a mention of taking statins to prevent the eye disease.

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  • It. Is exciting news news isn't it. I found the mention of using statins interesting because when my Graves was at its worst my cholesterol was the lowest it has ever been so looking at my figures then I didn't have high cholesterol and wouldn't (I hope) normally have been a candidate for statins.

  • Yes, I was exactly the same but now post TT my cholesterol levels now sit at 6.6 nmol, so I am 10% over range but after reading Dr Malcolm McKenzie's book 'The Great Cholesterol Con' I refused the statins. I am also aware the statins increase your chance by 1/3 of getting diabetes and my blood sugar is on the rise too. If anything stands out here they are suggesting they are developing a drug that can neutralise the antibodies so they don't attack either thyroid or eyes. For those still with their thyroids this will be a God send.

  • Statins also increase the risk of cataracts.

  • Yes, so it is kind of counterintuitive. Although I suspect the prospect of correcting cataracts is more achievable than correcting aggressive TED.

  • Great news ,I did not have high cholesterol until after my TT for Graves.And my eyes are far worst when i am under medicated.I do not take statins as my argument is that when i am adequately medicated my cholesterol is ok.Thanks for posting.

  • I'm with you on the statin decision but if it was temporary use to stop the eye disease then I would probably reconsider. In my case my eyes are now a major part of my misery and I would definitely consider the drug they are developing as a trial. I so wish this drug was available post TT and TED :-(

  • Me too.

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