Thyroid UK
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Pregnancy, PCOS, Metformin, NAX , NA in Devon

Hi you clever folk out there,

We are looking for a practitioner who can help our daughter in Devon. Aged 35, very early 2nd pregnancy after being prescribed metformin by GP for PCOS, absence of menstruation. Last period over 3 weeks long in Feb. She has also been taking NAX x1 and NA x 2 daily and feels much better on this, however label advice says not to take when pregnant.

NHS refuse endo appt as she is "in range with TSH" despite lots of hypo symptoms including extreme fatigue, low voice, acute and chronic muscle joint pains during and after last pregnancy. They also refuse gynae appt saying she has PCOS.

Private Health Insurance refuse referral saying she has PCOS.

I have Hashi's and am well on NHS precribed Sanofi- AventisCynomel. Her brother is coeliac.

Can anyone pm me re nutritionists/ kinesiologists / gynae / endo's or similar who prescribe NA in Devon North of Plymouth.

Thank you

8 Replies

Your daughter obviously has to have a very good doctor re her pregnancy.

Re PCOS. This is an extract which might be helpful. I don't have the link

Multiple Ovarian Cysts as

a Major Symptom of Hypothyroidism

The case I describe below is of importance to women with polycystic ovaries. If

they have evidence, such as a high TSH, that conventional clinicians accept as evidence

of hypothyroidism, they may fair well. But the TSH is not a valid gauge of a woman's

tissue thyroid status. Because of this, she may fair best by adopting self-directed

care. At any rate, for women with ovarian cysts, this case is one of extreme importance.

In 2008, doctors at the gynecology department in Gunma, Japan reported the case

of a 21-year-old women with primary hypothyroidism. Her doctor referred her to the

gynecology department because she had abdominal pain and her abdomen was distended

up to the level of her navel.

At the gynecology clinic she underwent an abdominal ultrasound and CT scan. These

imaging procedures showed multiple cysts on both her right and her left ovary.

The woman's cholesterol level and liver function were increased. She also had a

high level of the muscle enzyme (creatine phosphokinase) that's often high in hypothyroidism.

Blood testing also showed that the woman had primary hypothyroidism from autoimmune


It is noteworthy that the young woman's ovarian cysts completely disappeared soon

after she began thyroid hormone therapy. Other researchers have reported girls with

primary hypothyroidism whose main health problems were ovarian cysts or precocious

puberty. But this appears to be the first case in which a young adult female had

ovarian cysts that resulted from autoimmune-induced hypothyroidism.

The researchers cautioned clinicians: "To avoid inadvertent surgery to remove an

ovarian tumor, it is essential that a patient with multiple ovarian cysts and hypothyroidism

be properly managed, as the simple replacement of a thyroid hormone could resolve

the ovarian cysts."[1]


1. Kubota, K., Itho, M., Kishi, H., et al.: Primary hypothyroidism presenting as

multiple ovarian cysts in an adult woman: a case report. Gynecol. Endocrinol.,

24(10):586-589, 2008

Other members will respond if they have had similar problems.


Thank you Shaws, hope to find a good practitioner as close to Devon as possible - Article helpful and I think I may have a link to it stored from previous searches, thanks for reminding me ;-)


I hope you get a good doctor as we do deserve all the help we can get and that your daughter's pregnancy goes smoothly.


Thank you Shaws.


If you go to the thyroid UK website, they have a list of thyroid friendly doctors they can email you, contact is Louise warville, who is an admin on here. I'm not in Devon, but the one I used off the list has made a huge difference to my quality of life, and has been worth the cost. It may help.

1 like

Hi Sarah.

In view of your daughter's extreme fatigue, I wondered if she has had vitamin B12 tested. It's very important as pregnancy makes high demands on B12 and is vital for the baby's development

Metformin is one of the many drugs that deplete it.

Coeliac disease in your son is also one of the high risks for B12 deficiency and this, as well as autoimmune thyroid disease, is often interlinked and runs in families.

Kind regards


Thank you Polaris and Poshpenny,

Mmmm I take Lambert's Vit B12 100 complex, certainly good advice will check especially with the metformin link too. Son did take it for a while, most definitely one of the possible triggers if low.

Good thinking.


Just posting in case this thread is relevant to anyone else, Dr BDP has advised patient, in her case, to continue with NAX and NA.


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