Hashimoto's; higher dose, better chance of remi... - Thyroid UK

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Hashimoto's; higher dose, better chance of remission?

Chloececilia profile image
11 Replies

Hello.

I have been advised that the higher the dose of Carbimazole given the better chance there is of remission from the disorder.

What dose would be appropriate for this to be effective?

Thank you!

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Chloececilia profile image
Chloececilia
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11 Replies
Clutter profile image
Clutter

Chloececilia, Carbimazole is prescribed for hyperthyroidism which is often caused by Graves autoimmune antibodies. Carb regulates thyroid by blocking thyroid hormone. Carb has to be monitored monthly as it can act quickly and too high a dose will make the patient hypothyroid. If your hyperthyroidism isn't caused by Graves the chances of remission being permanent are much higher than if you have Graves.

Although it is possible to have Graves and Hashimoto's antibodies together, usually the patient presents with hyperthyroidism or hypothyroidism. Some Hashimoto's hypothyroid patients find suppressive doses of Levothyroxine can help prevent Hashi flares and reduce antibodies.

Chloececilia profile image
Chloececilia in reply to Clutter

Thank you Clutter. I'm really confused with it all. The endo said Hashimoto's, but everyone else I have spoken with has said, is it not Graves?

I was put on Carb and Propranolol before any antibody tests/diagnosis of type was made.

Surely he wouldn't just say Hashimoto's if there was a possibility it was Graves?

Clutter profile image
Clutter in reply to Chloececilia

Chloececilia, It is possible to be hyperthyroid and have Hashimoto's antibodies. Thyroid Peroxidase and Thyroglobulin are the antibody tests for Hashimoto's. Ask your endo whether Thyroid Receptor or Thyroid Stimulating Immunoglobulin antibodies were also tested as they will rule out or confirm Graves antibodies.

Chloececilia profile image
Chloececilia in reply to Clutter

Thank you Clutter. After my antibody test I only got results for Anti TPO, would they have automatically tested for all antibodies?

Clutter profile image
Clutter in reply to Chloececilia

It doesn't look like it, Chloececilia. You really should ask whether Graves antibodies were also tested. Seems odd to test TPOab but not for Graves in a hyperthyroid patient.

Chloececilia profile image
Chloececilia in reply to Clutter

Hello! I have just spoken to GP and they had also tested Thyroid Receptor which was:

3/L (0-15) and marked as normal no action.

Clutter profile image
Clutter in reply to Chloececilia

Chloececilia it looks like you are negative for Graves which is good news and the chance of remission is higher. Unfortunately, Hashimoto's may mean you will eventually become hypothyroid but that may take decades.

Chloececilia profile image
Chloececilia in reply to Clutter

Thanks Clutter, I was getting confused for a while there, now I get it! Thanks so much for all your advice so far.

Chloe

Heloise profile image
Heloise

Chloe, I think it should be calculated according to what you need to suppress your thyroid hormone to normal levels. The block and replace protocol seems backward to me but I'm not a medical professional. Sometimes a beta blocker is used along with your carbimazole. Stress is a large factor behind hyperthyroidism and that can be even a stress possibly from your diet.

stopthethyroidmadness.com/g...

Chloececilia profile image
Chloececilia in reply to Heloise

Thank you Heloise, I am also on Propranolol to control racing heart, anxiety and tremors but have managed to reduce my dose of them already.

Major stress has definitely been a part of my life for the past 6 or so months.

My current dose is 20mg p/day and my thyroid is settling quite nicely at that so I didn't see an immediate need for increase other than if there was a better chance of remission.

Looking back he did not have my TFT's there, I had to reel them off! Good thing I've written them down so many times :)

Heloise profile image
Heloise in reply to Chloececilia

youtube.com/watch?v=3_uaUXi...

youtube.com/watch?v=Z5SaM0R...

youtube.com/watch?v=cIKmuIf...

Maybe these videos will help.

[ Edited by admin to make links work. ]

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