T4/T3 - causing symptoms of overmed after 7 days - Thyroid UK

Thyroid UK

141,245 members166,490 posts

T4/T3 - causing symptoms of overmed after 7 days

Daffers123 profile image
10 Replies

Hello Everyone

here I am again, with more troubles. Hope someone can offer some advice please.

Having 'failed' a T3 only trial of 2 months which made me very ill (felt hyper all the time and could only gt my dose up to 18.5mcg split of Cynomel) last week I gave up and my endo thought we should try a combination of Levo and Cynomel. He put me on 50mcg Levo plus 6.25 ofT3 per day and I started last Friday night. I decided to take half the levo at bedtime and the rest on awakening with the T3.

For the first few days I felt tired after lunch but much better than on the T3 only, more calm, less anxious. Wed and yesterday I felt that I had turned a corner at last and hooray this could work. Ha ha.. Last night I wanted to keep eating, didnt sleep at all well, felt wired and tired, and this morning (took my meds as usual) but all day have felt overmedicated/hyper - pulse rate up, heart palps, shaky, hungry, brain fog, blurred vision etc. I still feel rubbish and shaky now and sick.

I weigh 7.5 stone (47 kilos) - is the dose too much for my weight. I am 58. Which do I cut down - the Levo, or T3 or both ?

I am intending to try DHEA asap but am worried to start it now. I am trying to support my adrenals with herbs as cant take glandulars.

Thanks in advance

Written by
Daffers123 profile image
Daffers123
To view profiles and participate in discussions please or .
Read more about...
10 Replies
Clutter profile image
Clutter

Daffers, it sounds as if the T4 has kicked in. It takes about 7/10 days. Try 25mcg T4 for 5/7 days and see whether the symptoms improve. If they do, try 25mcg/50mcg on alternate days for another week before increasing to 50mcg daily.

The dose isn't too much for your weight, I'm 46.4kg and taking 75mcg T4 + 30mcg T3.

Daffers123 profile image
Daffers123 in reply toClutter

As ever, thanks so much Jackie for your help. Do you ever wish you could put on a bit of weight - I know I do!

Her we go then on 25 a day . ...

Clutter profile image
Clutter in reply toDaffers123

Daffers, I'm as mad as a box of frogs about mine. I was 49kg in April (gawd bless caramel eggs). I was a little overmedicated and have just reduced dose and I'm force feeding myself whether or not I want food until I get >55kg.

gabkad profile image
gabkad in reply toClutter

"Mad as a box of frogs".......................oMg............LOL! Thanks Clutter. Appreciated it.

Eat bacon. Lots of bacon. Fry your eggs swimming in bacon fat. Dip your toast in it too. That'll get you nice and hippy. :)

Clutter profile image
Clutter in reply togabkad

Much as I lurve fried bread it doesn't love me back, Gabkad :( But I do love banana fried in bacon fat in buttered toast...dribble :-D

gabkad profile image
gabkad in reply toClutter

banana fried in bacon fat in buttered toast? Is that a typo or for real?

I didn't say fry the bread, just dip it. Sheesh. Smoked bacon.

Slow roasted pork belly..........get your glycine for your skin and bones....

See? Eat the caloric density stuff. Pass on the fluff.

Spaghetti carbonara. Fettucine alfredo.

Okay, that's it. I have the opposite of your problem.

This week-end I'm making a big batch (too many corn on the cob around here) Thai corn/shrimp/crab/coconut chowder....... That would put the meat on your bones for sure. But alas, I am too far away to feed you. :)

Clutter profile image
Clutter in reply togabkad

It's the nana fried in bacon fat and eaten as a toasted sarnie.

I love corn on the cob too (apart from the bits that stick in my teeth). The chowder sounds scrummy. Wish you lived next door.

I do pretty well on rib sticking casseroles, stews and thick soups in the winter.

Daffers123 profile image
Daffers123 in reply toClutter

55kg is what I was when I was well .. I just don't understand how we can be hypo but lose all that weight. I look like an ageing skeleton. Could you tell by symptoms that you were overmedicated or was it blood tests/urine tests ? Did you find the T3 caused you to lose your appetite - I really thought I was getting an eating disorder at one time

Must say I love the idea of fried banana in bacon fat - might try that for breakfast - and other stuff that you and Gabi have been musing about....am off to fry up some sausages now

x

Clutter profile image
Clutter in reply toDaffers123

Daffers, I've always been underweight for my height but I suddenly put on weight and went up almost 3 dress sizes in a few months. Felt and looked good though. I suspect that was the start of Hashi's kicking in. Dropped 13kg in 10months and was having awful hypo and hyper symptoms and lump appeared in my neck. TSH 2.30 and antibodies 230 so no treatment until thyroidectomy as thyCa found after partial thyroidectomy to remove large nodule. I lost another 4kg after starting Levo and it fluctuates between 45 and 49kg since.

cc120 profile image
cc120

Some adrenal support info from other threads:

groups.yahoo.com/neo/groups...

You will want to make sure you are supporting your adrenals. Adrenals run on salt, so you want to get some of the unprocessed sea salt, like Celtic Sea Salt and take 1/4-1/2 tsp in 16 oz of water several times per day. Plus, you want to get a good ionized multimineral, a good multi B like Swanson's Activated B's with methylfolate not folic acid and around 1000 mg of a real vit. C and not ascorbic acid per day. Sublingual methyl b12, 500-1000 mcg, can be very helpful as well as magnesium at 5 mg per pound of body weight. Making your adrenals happy can help with weight issues.

Some have found 200 mg of selenium per day have helped bring down antibodies:

stopthethyroidmadness.com/s...

medhelp.org/posts/Thyroid-D...

I worked on my adrenal repair as natural as I could. I supported them with DHEA-5 - sea salt and high levels of Vit C to repair them. The adrenals are complicated - if not more so - than thyroid can be for a patient and treatment/conditions vary widely from patient to patient. I found good things doing this treatment plan and why I chose it was I wanted to not go to extreme levels to medicate if not needed - ie - HC treatment.

DHEA adrenal support, also for depression

Not what you're looking for?

You may also like...

T3 only not working

Hi all Am on my second month of Cynomel only and it doesn't seem to be working. Had to stop Levo as...
Daffers123 profile image

Testing T3/T4 Combo

I've recently started the combo treatment. I take 125 Levo in the morning with 10mcg T3 and 5mcg...

T4 and T3 Combo

I'm new on here and looking for advice. My endo added 10mcg of T3 to my 100mcg of Levo as i wasn't...

NDT Vs T3 & T4 ??

Hi - Been on levo 150mg and Cynomel 0,025 mg since December - I was only on 50mg of levo a year...
cazza1001 profile image

After 5 yrs Cytomel causing headache and nausea

I'm a patient of Dr Peatfield and I've been taking Cynomel the past 5 years, with Nutri Thyroid...
janetah12 profile image

Moderation team

See all
Jaydee1507 profile image
Jaydee1507Administrator
PurpleNails profile image
PurpleNailsAdministrator
SlowDragon profile image
SlowDragonAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.