New here. First time poster, so be gentle. Thyroid blood panel results

Has anyone experienced having a lifetime of elevated TSH levels with normal T3&T4 panel results? TSH elevation usually goes ignored if T3&T4 show normal. There is a reason the pituitary gland keeps asking for increased production, yet goes ignored by the thyroid. A failure in pituitary or hypothalamus production, maybe? Going in to demand a full list of panels, hoping to tack it down, soon but doctors are quick to dismiss this elevation as long as the thyroid is not responding to it. It is considered trivial. Hoping to find one that will entertain the theory.

3 Replies

  • Welcome to the forum, Skizzy.

    If you can post your recent thyroid results with the lab ref ranges (the figures in brackets after your results) it will help members to advise.

    Elevated above range TSH with in range FT4 and FT3 is described as subclinical hypothyroidism but in the absence of autoimmune thyroid antibodies which will eventually lead to overt hypothyroidism ie TSH >10 with low FT4 and FT3 many doctors decline to diagnose and treat.

    If you want a list of recommended private GPs and NHS and private endocrinologists email

  • Do you have hypothyroid symptoms? I am assuming you have some kind of symptoms because clearly you have been seeing a doctor. Have you ever been prescribed Levothyroxine and if so what effect did it have? The 'normal' ranges for T4 and T3 are quite broad. A lot of people feel quite bad with T3 and T4 levels within the normal range, and only start to feel well when their T3/T4 levels are in the top 75% of the normal range.

  • A high TSH with normal T3 and T4 and hypothyroid symptoms could be indicative of Thyroid Hormone Resistance. There are a number of genetic syndromes which can cause this and as it is genetic you can expect some other family members to have thyroid issues.

    The hypothyroid symptoms are caused by a failure to get sufficient T3 to bind to the receptors within the cells. The treatment is to take a high daily dose of T3 which enables sufficient T3 to bind to the receptors.

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