If hypothyroid the best way to reduce cholesterol (a clinical symptom of hypo) is adequate and optimum medication of thyroid gland hormones (levo or other alternatives). This is an excerpt:-
Hypothyroidism is often accompanied by diastolic hypertension that, in conjunction with the dyslipidemia, may promote atherosclerosis.
However, thyroxine therapy, in a thyrotropin (TSH)-suppressive dose, usually leads to a considerable improvement of the lipid profile. The changes in lipoproteins are correlated with changes in free thyroxine (FT(4)) levels.
and another excerpt
The aim of this study was to assess the changes in serum lipid profiles after replacement therapy with thyroxine in patients with subclinical hypothyroidism (SCH) and to see whether there is an improvement in dyslipidemia based cardiovascular risk. 30 non-smoker pre-menopausal women with newly diagnosed (SCH) (TSH between 4 and 10) were involved in the study and 26 euthyroid healthy subjects were used as the control group. All patients were tested for TSH, FT3, FT4, total cholesterol (TC), triglyceride,(TG) HDL cholesterol (HDL) and LDL cholesterol (HDL-C). These tests were taken before thyroxine was given and again 6 months after thyroxine was given. The patients with SCH had significantly higher levels of TC and LDL-C. After six months the TC, LDL-C levels and the TC/HDL-C ratio were reduced significantly. In conclusion, even mild elevations of TSH are associated with changes in lipid profile significant enough to raise the cardiovascular risk ratio, and these changes are corrected once the patients have been rendered euthyroid.
My cholesterol reduced when on levo.