I had to reduce thyroxine dose from 150 mcg daily down to 100mcg one day and 75 mcg the next ,over a peroid of 5 months as I had gone hyper.

[susiebow]

Now crawling back up again,increased dose to 100 mcg daily,did feel bit better for 5 weeks ,but then felt unwell again my TSH is going up despite increase,does this mean I need to increase my dose further.

[Clutter]

Yes, as your TSH increases a larger dose of levothyroxine is required to bring it within range.

Have your Thyroid Peroxidase antibodies been tested? Sounds like you may have auto-immune thyroiditis (Hashimoto's) which fluctuates as your thyroid sputters into life and back to useless again.

[susiebow in reply to Clutter]

Thankyou ,yes you are right antibodies 399.Thanks for clarifying things for me ,this site is such a hep.

[Hennerton]

Yes, but some blood results would be helpful to see what has been happening. If your GP doses by TSH, he may have reduced your dose when not necessary.

[susiebow in reply to Hennerton]

Thanks ,think you are right,I will be more on the ball from now on.

[PinkNinja]

That is a huge decrease! Essentially your dose was halved which is much to drastic unless you were experiencing tachycardia of atrial fibrillation or something similar. A drastic decrease like that would normally only be required for a couple of weeks to bring the levels down before increasing again. I think yours might have been left too low for too long.

I agree with the others that you probably need to increase again.

I hope you start to feel better soon

Carolyn x

[Chippysue]

Going by your free t4 would be far more helpful. Is it at the top or just above the lab range?