Thyroid UK
87,645 members102,338 posts

should I take my T3 with my T4?

I have recently started to take T3 and just starting to feel the benefits, but I have been taking it about 4 hours after the T4 which i take at 6am, so I don't feel too well till the afternoon, I just wondered what experience others have had and also should T3 also be taken away from food and milk as in T4?

I would be so grateful for any advice please.

thanks, Sue x

9 Replies

People on here are divided as far as T3 and food/drink are concerned. I can only say that through personal experience food/drink did affect the way my body used the T3 so I use to take it as I would T4. If it is not going to be an issues to take it away from food I would try that first to see how you get on but if you find its to difficult to keep it away from food you'll have no other option but to take it with food and see if you notice a difference.

What works for me might not work for you and vice versa - you may need to try a few different ways to see what suits you.

Moggie x


There is no problem in taking your T4 and T3 together, as I have done in the past. Dr Lowe also advised a once-a-day regime.


I take my T4 and first dose of T3 together in the morning and then wait about an hour before I have breakfast. However, I take the other two doses of T3 near meal times. I have tried taking T3 away from food and near food and for me it doesn't seem to make any difference.

I think it's trial and error.

1 like

This is advice and excerpt from Dr. Lowe

Dr. Lowe: As a rule, our patients take thyroid hormone only once per day. An advantage of this one-per-day schedule is that it’s easier to find a window for good intestinal absorption—when the stomach or small intestine doesn’t contain food.

Most of our patients wait at least one hour after taking thyroid hormone before they eat. Or they wait at least two hours after eating before they take thyroid hormone. The two hour wait is a rough estimate of the time it takes for food to pass through the stomach and small intestine. It’s worth noting, however, that several factors can increase the time a patient should wait before taking thyroid hormone.


Thanks so much for all your advice, I think I will take my T3 along with the T4 in the morning and see how I go, I will have to increase my dose a little to take a top up in the afternoon/teatime?

Its such a help to have this site and know you are not alone and others can share all their experiences etc!

I am taking the 25mcg from the Mexican pharmacy and take half so I will perhaps top it up with another quarter later in the day,

many thanks again, xx


It is very much personal preference. I seem to have a really big problem with t4 to the extent that just stopping levo saw an improvement in how I felt initially. I found that I couldn't take any t4 at the same time as t3. It has to be at different times of day for me. I have had to eventually resort to t3 only though. Some people find they have a reverse t3 problem if they take t3 and t4 at the same time. Others find that they are better taking them at the same time.

As far as food goes, that also depends on the individual. I need a slightly higher dose if I take it with food but I also find I don't get that'rush'of t3 if I have no food around each dose. Swings and roundabouts.

You will probably have to experiment with timings to find what works best for you.

I hope adding t3 helps you to fell better :)

Carolyn x


Thanks Carolyn, it really does show how different we all are! I will have to find out what suits me through trial and error, will get there in the end! thank goodness for this place!

best wishes, xx


I take my T3 by placing under the tongue and letting it dissolve. It does not have any taste and it solves all the dilemas about not being near food. It dissolves very quickly and goes straight into the blood stream and gets to work within a couple of minutes. I do not have any problems with a"rush" but it does get me up and doing things! As I take it regularly throughout the day, it also solves the problem of having to find a liquid to swallow with a tablet.



Thanks very much Heather, that sounds an excellent way to take them and may help me judge the amount I need, T3 doesn't seem to have to be so exact as T4,

take care, xx


You may also like...