Has anyone changed from NDT Erfa back to Thyro... - Thyroid UK

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Has anyone changed from NDT Erfa back to Thyroxine and if so please would you share the process? I am currently taking 90mgs Erfa

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Heloise profile image
Heloise

I may be wrong but I think very few people do that since NDT is the preferred treatment for most people. Saying that, I would think you could just make the switch using the equivalent amount of T4 to what dose you are taking of Erfa which appears to be one and one half grain. I think it would be 150 mcg of thyroxine but you could research this at stopthethyroidmadness.com/l... or any other source of thyroid information for exact ratios. Are you really sure you want to do this?

Alli1 profile image
Alli1

Hi Heloise thank you for your reply. No I'm not truly convinced that I want to make the change however I have been on Erfa for two yrs now and I seem to be very sensitive to the T3 - I get peaks and troughs and sometimes these are difficult to tolerate. Also have noticed some anxiety recently and have difficulty sleeping. My (private) Endo and I have discussed the symptoms and he feels it might be worth having a trial of T4 replacement. I do currently take 25mcgs of Thyroxine with the Erfa. I am of course very nervous to do this trial as I'm expecting some unpleasant symptoms during the transition so that's why I posted on this forum to check if anyone else has tried to make this change. I was on 100mcgs of thyroxine for about 10yrs previously and was stable enough on that dose. However three yrs ago I hit a bad patch and that is why I commenced Erfa. I'm very anxious at the thought!!

Hi, that must be very frustrating for you. I was like you, very stable on thyroxine for about 6/7 years and then hit a bad patch. Increase in levo didn't improve things so recently went on a T4/T3 combo and thats not proving to be the answer either, well not yet anyway but it may be early days. I suppose you have had all the obvious checks done for adrenals, Vit D3, B12, ferritin, folate iron etc. If any of these are deficienct, no amount of thyroid replacement will work. Do you have Hashi's?

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Alli1

Sorry that I haven't replied earlier, I'm not sure that it is Hashis as never had the correct tests but I think it is as both my mother and sister are hypo so I'm guessing it's an autoimmune condition which would mean Hashis?

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