Hi guys. Haven't been on here in a long time but recently I seem to have come across a combination of meds & supplements that really seem to have worked for me. So I've had IBS for over 30 years (mainly IBS C but regular episodes of IBS D too) and more or less managed it for many years, up until entering peri-menopause with all the delightful symptoms that comes with that. I ended up on HRT for about 6 years (it was that or divorce) and it became apparent that my IBS had become so much worse, to the point I wouldn't eat if I had to go anywhere. I did a bit of research and discovered that HRT can have an adverse affect on IBS sufferers, so after weighing up the risks of coming off HRT against the impact of my IBS, I decided to stop the HRT. Withing a month or so there was some improvement with my IBS (and my menopause symptoms were manageable) but still wasn't great. I was taking alverine/audmonal meds plus a 50 billion probiotic. Then a routine blood test showed I was low in folate (folic acid) so I was prescribed folic acid tablets to take for 4 months. And boy, what a difference that made!!!! I went from having a BM maybe once a week with an 'explosion' every couple of weeks to going regularly every single day! I haven't been like that for years!! Anyway, after the 4 months I stopped the folic acid, and things went downhill. So I bought some folic acid with Vit D3 to take daily, and hey presto, back to being regular again. So it would appear the combination of the alverine, probiotic and folic acid is the holy grail for me. If I forget to take one of them (normally the probiotic) then I can definitely tell, but as soon as I get back on track things improve.
Not sure if folic acid is a big factor in IBS, but this really seems to have worked for me so maybe it might work for others.