Yes, I too got constipation after a couple of months on Alflorex, but decided that was better than IBS-D. I did try reducing the dosage, but that caused the IBS-D to resurface. According to the manufacturers, this species of bifidobacterium does not colonise the gut, so you have to keep taking it. It actually works by helping the other "good" bacteria thrive in the gut, rather than being part of the normal microbiome; having followed the Zoe programme, it seems that no-one knows why this is, but many of the "good" bacteria in fermented foods act in the same way.
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