IBS-d and fecal transplant

[Janhow]

Hi this is my first post on this site. Ive suffered with ibs-d for many years with number of loo trips increasing up to last three or four years. Now take loperamide daily at night which at least gives me majority of day after 11am with relative confidence.

I have read varying reports that faecal transplant can help and wondered if anyone has had any success?

[xjrs]

Funnily enough I was having a discussion about this on this forum recently. This is what I put:

Unfortunately there are major risks with fecal transplant therapy (FMT) in that potentially you could pick up health problems from other people from it:

bmjopengastro.bmj.com/conte...

Gut microbiome is thought to be associated with many GI and non-GI conditions including diabetes, metabolic syndrome, obesity, colon cancer and many others. Just as FMT is being explored in its utility to alter certain conditions, the opposite could be true. At least theoretically, FMT from a donor with certain disease phenotype could potentially transmit the disease to the recipient. Data on long-term safety of FMT is lacking.....A total of 4 of the 77 patients reported a new medical condition after FMT including peripheral neuropathy, Sjogren's disease, idiopathic thrombocytopenic purpura and rheumatoid arthritis.

I believe that the moment it is only considered for clostridium difficile infection where antibiotics have failed to treat it and the patient is at risk anyway....

I saw a TV program in the UK. A mother who was slim, athletic and never had problems with her weight who had C Dif, had a fecal transplant from her daughter who was obese and the mother then became obese. There seems to be a lot about the microbiome that contributes to other health factors.

Here is the whole thread:

healthunlocked.com/theibsne...

Personally I wouldn't try it myself due to the current risks, especially until a safe way has been found of doing it.

[Janhow in reply to xjrs]

Thanks for your reply. That’s a bit more to think about!

[xjrs in reply to Janhow]

Let me know if you want tips about managing IBS, hopefully so you don't need loperamide so much. I can pm you the details if you want?