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half life T3 in NDT
I've read over a period of time that T3 has half-life of anywhere from 2-2.5 days. I have, always, assumed (bad thing!) that was for synthetic T3. Anyone know, if that time-frame is applicable to dessicated T3? My FT3 shot up from 2.7 in late Feb. to 3.85 2 weeks ago. I had increased dose from97.5
I've read over a period of time that T3 has half-life of anywhere from 2-2.5 days. I have, always, assumed (bad thing!) that was for synthetic T3. Anyone know, if that time-frame is applicable to dessicated T3? My FT3 shot up from 2.7 in late Feb. to 3.85 2 weeks ago. I had increased dose from97.5
terebol
in
Thyroid UK
2 months ago
Has anyone taken Relugolix from start and no injections of ADT ?
Is relugolix reliable as compared to the adt injections ? Has anyone been only on that and not the injections ? How soon does it bring the testosterone levels down as compared to the injections ? I am in India and it is available here at around 100 dollars for a box of 30 tablets of 120 mg each
Is relugolix reliable as compared to the adt injections ? Has anyone been only on that and not the injections ? How soon does it bring the testosterone levels down as compared to the injections ? I am in India and it is available here at around 100 dollars for a box of 30 tablets of 120 mg each
Tinkudi
in
Advanced Prostate Cancer
2 months ago
Giving levo another go...
Hi thyroid community, I have been diagnosed with 'sub clinical' hypothyroidism (due to autoimmune condition) in the last few years and my life has been shit ever since as I'm sure many can relate. I didn't get on very well with levothyroxine during my first trial, but I decided to persist giving it
Hi thyroid community, I have been diagnosed with 'sub clinical' hypothyroidism (due to autoimmune condition) in the last few years and my life has been shit ever since as I'm sure many can relate. I didn't get on very well with levothyroxine during my first trial, but I decided to persist giving it
rainbowcabbage
in
Thyroid UK
2 months ago
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Do all get baseline testosterone before starting ADT
my MO had told to do a testosterone test two weeks after starting ADT but I was wondering do most do that or also get one before starting ?
my MO had told to do a testosterone test two weeks after starting ADT but I was wondering do most do that or also get one before starting ?
Tinkudi
in
Advanced Prostate Cancer
2 months ago
Kishan's 6 month Androgen Annihilation Therapy Study for metastatic PCa
https://x.com/prostatecell/status/1770206641813696808?s=46 https://bit.ly/43rr68x seems to be a promising tactic for oligometastatic PCa, that combines SBRT with an ADT mix . The Abstract starts off by noting that with metastatic hormone sensitive PCa, recurrence almost always happens within six months
https://x.com/prostatecell/status/1770206641813696808?s=46 https://bit.ly/43rr68x seems to be a promising tactic for oligometastatic PCa, that combines SBRT with an ADT mix . The Abstract starts off by noting that with metastatic hormone sensitive PCa, recurrence almost always happens within six months
Xavier10
in
Advanced Prostate Cancer
2 months ago
PSA Still Going Up
I had RP on January 2023, started ADT in May 2023 and went through 38 sessions of radiation. In November 2023, my PSA went down to 0.005 ng/mL. My PSA went up to 0.015 ng/mL in January 2024 and went up to 0.035 ng/mL in my current test. I know Tall Allen said the previous number was negligible because
I had RP on January 2023, started ADT in May 2023 and went through 38 sessions of radiation. In November 2023, my PSA went down to 0.005 ng/mL. My PSA went up to 0.015 ng/mL in January 2024 and went up to 0.035 ng/mL in my current test. I know Tall Allen said the previous number was negligible because
toyman79912
in
Advanced Prostate Cancer
2 months ago
PSA 8 months after EBRT
I need some reassurance. I tend to worry a little bit so please let me know if the following is or could be somewhat normal. As per my history, I had 4+3 per Dr. Epstein, had Pylarify with no mets, seed implant LD brachytherapy in July 2023, EBRT 28 treatments finishing first of Oct 2023. RO said ADT
I need some reassurance. I tend to worry a little bit so please let me know if the following is or could be somewhat normal. As per my history, I had 4+3 per Dr. Epstein, had Pylarify with no mets, seed implant LD brachytherapy in July 2023, EBRT 28 treatments finishing first of Oct 2023. RO said ADT
electronics-guy
in
Prostate Cancer Network
2 months ago
Why does Levothyroxine cause weight gain if it treats hypothyroidism, weight gain being a hypo symptom?
Shouldn't it help rectify hypo symptoms not make them worse? This baffles me! I wish I could revert back to Levothyroxine and use it together with T3 as NDT is extortionately priced, and not working brilliantly for me anymore, however, weight gain is my biggest fear, and I read so much about this on
Shouldn't it help rectify hypo symptoms not make them worse? This baffles me! I wish I could revert back to Levothyroxine and use it together with T3 as NDT is extortionately priced, and not working brilliantly for me anymore, however, weight gain is my biggest fear, and I read so much about this on
MindfulMoments
in
Thyroid UK
2 months ago
Hot flashes?
On ADT and suffering? https://www.medpagetoday.com/meetingcoverage/asco/110457?xid=nl_mpt_morningbreak2024-06-04&eun=g2046106d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=MorningBreak_060424&utm_term=NL_Gen_Int_Daily_News_Update_active That might help. I'm no longer on ADT so I can't speak
On ADT and suffering? https://www.medpagetoday.com/meetingcoverage/asco/110457?xid=nl_mpt_morningbreak2024-06-04&eun=g2046106d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=MorningBreak_060424&utm_term=NL_Gen_Int_Daily_News_Update_active That might help. I'm no longer on ADT so I can't speak
Don_1213
in
Prostate Cancer Network
2 months ago
Should I be worried about suppressed TSH
I am extremely well and all my bloods seem within normal range to me (but not the GP)! I am 61 years old and was diagnosed with Hashimotos Thyroditis and Chronic Fatigue in 2004. My only health issue is very erratic sleep (one night 8 and a half hours, the next 4) which I handle by resting in the afternoon
I am extremely well and all my bloods seem within normal range to me (but not the GP)! I am 61 years old and was diagnosed with Hashimotos Thyroditis and Chronic Fatigue in 2004. My only health issue is very erratic sleep (one night 8 and a half hours, the next 4) which I handle by resting in the afternoon
YoginiDancer
in
Thyroid UK
2 months ago
Experiences of NDT v Levo and Lio
Hello again, I have been trialling NDT (2 grains since mid March 2024. I was previously on 75mcg Levo and 10mcg Lio (from NHS Endo) but still had symptoms. Both T4 and T3 levels are better on NDT yet I’m not feeling improvement. The private GP I saw increased my dose to 2.25 grains and I felt jittery
Hello again, I have been trialling NDT (2 grains since mid March 2024. I was previously on 75mcg Levo and 10mcg Lio (from NHS Endo) but still had symptoms. Both T4 and T3 levels are better on NDT yet I’m not feeling improvement. The private GP I saw increased my dose to 2.25 grains and I felt jittery
Piglet1956
in
Thyroid UK
2 months ago
Best alternative PET for PSMA negative PCa
Asking for a friend. He was diagnosed 3 years ago with high risk high volume (Gleason 3+5) PCa. Treated with EBRT + LDRBT + ADT (18 months). His PSA was undetectable but is now rising (3+) but PSMA-PET was negative, even in the prostate - implying PSMA non-avid cancer. What would be the best non-PSMA
Asking for a friend. He was diagnosed 3 years ago with high risk high volume (Gleason 3+5) PCa. Treated with EBRT + LDRBT + ADT (18 months). His PSA was undetectable but is now rising (3+) but PSMA-PET was negative, even in the prostate - implying PSMA non-avid cancer. What would be the best non-PSMA
Vynbal
in
Advanced Prostate Cancer
2 months ago
Anyone above 80 years -on triple therapy ?
Anyone over 80 years who has taken triple therapy - first and second generation ADT as well as chemo ? Could you please share how your experience of it was.
Anyone over 80 years who has taken triple therapy - first and second generation ADT as well as chemo ? Could you please share how your experience of it was.
Tinkudi
in
Advanced Prostate Cancer
3 months ago
Why is my TSH so low when my T4 T3 are so low?
Hi all can some please explain why my TSH is low despite my T4 T3 being low. Correct me if i have got it wrong but i have come to understand that TSH is released by the pituitary gland to stimulate release of more thyroid hormones if levlels are too low. Since 1993 i dont have a thyroid so i am on
Hi all can some please explain why my TSH is low despite my T4 T3 being low. Correct me if i have got it wrong but i have come to understand that TSH is released by the pituitary gland to stimulate release of more thyroid hormones if levlels are too low. Since 1993 i dont have a thyroid so i am on
DizzyD
in
Thyroid UK
3 months ago
Understanding the Threat of Micrometastases (also known as Minimal Residual Disease) in Prostate Cancer or Don't sweat the small stuff
Greetings followers of FPC; It is time to set things straight in regards to the oligometastatic state in prostate caner. Posters will tell you that it does not exist because of micrometastases. So let's take a look at micrometastases first. The dreaded micrometastases.....the ultimate death sentence
Greetings followers of FPC; It is time to set things straight in regards to the oligometastatic state in prostate caner. Posters will tell you that it does not exist because of micrometastases. So let's take a look at micrometastases first. The dreaded micrometastases.....the ultimate death sentence
NPfisherman
in
Fight Prostate Cancer
3 months ago
ADT failure
We saw my Dad's MO on 5/23. Over the course of 4 weeks my dad's PSA moved from 1.46 to 2.14, He said we need to be on Zytiga for three months before we can deem it a failure, but just like Xtandi, it appears my dad had limited help with it. We have talked about the next steps, chemo and pluvicto. My
We saw my Dad's MO on 5/23. Over the course of 4 weeks my dad's PSA moved from 1.46 to 2.14, He said we need to be on Zytiga for three months before we can deem it a failure, but just like Xtandi, it appears my dad had limited help with it. We have talked about the next steps, chemo and pluvicto. My
lgutman
in
Advanced Prostate Cancer
3 months ago
I want to give up. I have no energy to keep going.
Hi all, I've been suffering for the past many years. Since 2022 everything went downhill and I had to quit my job as I can't function. I'm 40 years old. I was tested for everything under the sun and everything is down to thyroid. I have Hashis. I have tried many med combos, everything fails on me. Recently
Hi all, I've been suffering for the past many years. Since 2022 everything went downhill and I had to quit my job as I can't function. I'm 40 years old. I was tested for everything under the sun and everything is down to thyroid. I have Hashis. I have tried many med combos, everything fails on me. Recently
Incoguto
in
Thyroid UK
3 months ago
Side effect of Lupron
We have a quesiton about swelling foot and ankle after Lupron injection and wonder if anyone has had a similar experience. My husband was just diagnosed with PC back in April, and he is on ADT while waiting for his CK treatment this month. After three-weeks of Lupron injection, he now has a swollen
We have a quesiton about swelling foot and ankle after Lupron injection and wonder if anyone has had a similar experience. My husband was just diagnosed with PC back in April, and he is on ADT while waiting for his CK treatment this month. After three-weeks of Lupron injection, he now has a swollen
kiyo
in
Prostate Cancer Network
3 months ago
Hypogonadism, heat flushing, and testosterone replacement
Hi all, It is almost a year since I had my external beam radiation for Gleason 7 (3+4) PCa (see my profile). So far so good: 4 PSA tests were reassuringly low. I am now almost 82 and I am hoping to deal with my strange heat-flushing problem, which I have had for several years. It predates my cancer
Hi all, It is almost a year since I had my external beam radiation for Gleason 7 (3+4) PCa (see my profile). So far so good: 4 PSA tests were reassuringly low. I am now almost 82 and I am hoping to deal with my strange heat-flushing problem, which I have had for several years. It predates my cancer
Smarks42
in
Prostate Cancer Network
3 months ago
Ultrahypofractional RT and ADT for Int. Risk PC
I am a 60 year old recently diagnosed PC with a PSA of 11.3 and ultra sound biopsy grade cT1c Gleason 3+4 = 7 Right basal and 3+3 on Right medial only 2 of 12 cores contain cancer. MRI showed PI Rads 5 lesion in right basal peripheral zone and extension into right seminal vesicle. Chose to go with
I am a 60 year old recently diagnosed PC with a PSA of 11.3 and ultra sound biopsy grade cT1c Gleason 3+4 = 7 Right basal and 3+3 on Right medial only 2 of 12 cores contain cancer. MRI showed PI Rads 5 lesion in right basal peripheral zone and extension into right seminal vesicle. Chose to go with
Hidden
in
Prostate Cancer Network
3 months ago
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