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better delivery for better results: nanolipid particles work well in vivo
”Mitchell and postdoctoral fellow Lulu Xue were able to achieve therapeutic mRNA delivery into the lungs, helping to eradicate metastatic lung cancer in preclinical mouse model studies. ” https://www.thedp.com/article/2024/04/penn-lipid-nanoparticles-michael-mitchell-research
”Mitchell and postdoctoral fellow Lulu Xue were able to achieve therapeutic mRNA delivery into the lungs, helping to eradicate metastatic lung cancer in preclinical mouse model studies. ” https://www.thedp.com/article/2024/04/penn-lipid-nanoparticles-michael-mitchell-research
Maxone73
in
Advanced Prostate Cancer
5 days ago
Surgery or radiotheraphy?
Hi, I writing this post on behalf if my husband who is 41 and was diagnosed with an acoustic neuroma in January. He has been referred to The Queen Elizabeth under Richard Irving and we had a lengthy discussion last week about options as the tumour is at a size where it needs treatment. My husband is
Hi, I writing this post on behalf if my husband who is 41 and was diagnosed with an acoustic neuroma in January. He has been referred to The Queen Elizabeth under Richard Irving and we had a lengthy discussion last week about options as the tumour is at a size where it needs treatment. My husband is
Zhad
in
Acoustic Neuroma Support
5 days ago
Does Immunotherapy cause Vasculitis?
Hi, my Mum had vasculitis in 2013 following a bad infection, she continues to take 5mg prednisone to this day.Sadly she has been diagnosed with a stage 2 tumor of the cecum which because of her age and frailty at 81 years old is suggested to be inoperable. Genetic testing reveals its a type of cancer
Hi, my Mum had vasculitis in 2013 following a bad infection, she continues to take 5mg prednisone to this day.Sadly she has been diagnosed with a stage 2 tumor of the cecum which because of her age and frailty at 81 years old is suggested to be inoperable. Genetic testing reveals its a type of cancer
luggsey
in
Vasculitis UK
5 days ago
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What to expect with mets and no treatment
4 months of study everywhere online- future life reading all the suffering here on this forum with side effects, impotence, recurrence, hormone therapy, other side effects, etc. My heart goes out to all of you, and my hats off to you warriors, who have chosen to fight this battle with conventional
4 months of study everywhere online- future life reading all the suffering here on this forum with side effects, impotence, recurrence, hormone therapy, other side effects, etc. My heart goes out to all of you, and my hats off to you warriors, who have chosen to fight this battle with conventional
Nwdx
in
Advanced Prostate Cancer
5 days ago
Weightlifting (machines) during SBRT?
(duplicate post) I am starting my five SBRT sessions tomorrow, April 29, 2024. I was not supposed to lift over ten pounds between my MRI/CT scan to locate my fiducials and my SBRT. I miss my workouts. Can I return to the gym with workouts on machines that isolate my muscle groups and avoid stress
(duplicate post) I am starting my five SBRT sessions tomorrow, April 29, 2024. I was not supposed to lift over ten pounds between my MRI/CT scan to locate my fiducials and my SBRT. I miss my workouts. Can I return to the gym with workouts on machines that isolate my muscle groups and avoid stress
Worked_the_World
in
Advanced Prostate Cancer
6 days ago
first recurrence
hi peeps , I started new rounds of chemo for floating cluster cells , detected after they drained 2.5 L of fluid from my belly. CA 125 820 I’m on Carboplatin / gemcitabine Did anyone had the same?
hi peeps , I started new rounds of chemo for floating cluster cells , detected after they drained 2.5 L of fluid from my belly. CA 125 820 I’m on Carboplatin / gemcitabine Did anyone had the same?
Vegana
in
My Ovacome
6 days ago
Alimta - Fevers
My mum has been fighting this disease since 2016. At diagnosis she was high grade OC stage 3c. After initial surgery and chemo she was in remission for 5 years but unfortunately the beast returned in 2021 and since then she has been under constant treatment. Her last scan a few months back showed
My mum has been fighting this disease since 2016. At diagnosis she was high grade OC stage 3c. After initial surgery and chemo she was in remission for 5 years but unfortunately the beast returned in 2021 and since then she has been under constant treatment. Her last scan a few months back showed
ShamilaS
in
SHARE Ovarian Cancer Support
6 days ago
Fevers
My mum has been fighting this disease since 2016. At diagnosis she was high grade OC stage 3c. After initial surgery and chemo she was in remission for 5 years but unfortunately the beast returned in 2021 and since then she has been under constant treatment. Her last scan a few months back showed
My mum has been fighting this disease since 2016. At diagnosis she was high grade OC stage 3c. After initial surgery and chemo she was in remission for 5 years but unfortunately the beast returned in 2021 and since then she has been under constant treatment. Her last scan a few months back showed
ShamilaS
in
My Ovacome
6 days ago
Starting Chemo in May via trial
Thanks to everyone for all of their great questions and converstions on this site. Check my bio for background. 2 months into ADT therapy after diagnosis in January. I am starting docetaxyl chemo via an NIH trial in May. M9241 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230972/. We are hopeful
Thanks to everyone for all of their great questions and converstions on this site. Check my bio for background. 2 months into ADT therapy after diagnosis in January. I am starting docetaxyl chemo via an NIH trial in May. M9241 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230972/. We are hopeful
4tunate1
in
Advanced Prostate Cancer
7 days ago
2 questions
I haven't recd a notice fr the Health Unhlocked PMR forum in months. I see I am still registered tho and my preferences recorded. Any idea why? Has something changed? Opps Guess its 3 questions. LOL In the dept. of stressors that can lead to flares, I learned last summer that death of a loved
I haven't recd a notice fr the Health Unhlocked PMR forum in months. I see I am still registered tho and my preferences recorded. Any idea why? Has something changed? Opps Guess its 3 questions. LOL In the dept. of stressors that can lead to flares, I learned last summer that death of a loved
bonmaine
in
PMRGCAuk
8 days ago
Prostate Cancer Diet and Re-purposed Meds
I was just reading a post about Jane Mcclelland's protocol regarding her book, "How to starve cancer." She also added a second portion on a book re-released, with a Ferroptosis (death by iron) protocol. I thought the criticism to be amazing. Cancer is a baffling mystery, top scientist and great minds
I was just reading a post about Jane Mcclelland's protocol regarding her book, "How to starve cancer." She also added a second portion on a book re-released, with a Ferroptosis (death by iron) protocol. I thought the criticism to be amazing. Cancer is a baffling mystery, top scientist and great minds
PlantrichyRich
in
Advanced Prostate Cancer
8 days ago
GemCarbo and picc line advice please!
Hi ladies, I've seen my oncologist today (well, one of his minions anyway) to find out about my treatment plan for my first recurrence. They've told me that I'll have gemcitabine with carboplatin this time round, so I was just wondering if anyone had any advice about this regime please? Even though carbotaxol
Hi ladies, I've seen my oncologist today (well, one of his minions anyway) to find out about my treatment plan for my first recurrence. They've told me that I'll have gemcitabine with carboplatin this time round, so I was just wondering if anyone had any advice about this regime please? Even though carbotaxol
Kjpip
in
My Ovacome
8 days ago
Surviving cancer: some options for you to consider
I just want to share with you all, that I was diagnosed with a T3 (5cm) Tumour called Adenocarcinoma, situated in the junction of the lower oesophagus and upper G. I (stomach) in January. Last year I kept complaining of : chest pains, sore tongue and throat, thick mucus and not being able to gain weight
I just want to share with you all, that I was diagnosed with a T3 (5cm) Tumour called Adenocarcinoma, situated in the junction of the lower oesophagus and upper G. I (stomach) in January. Last year I kept complaining of : chest pains, sore tongue and throat, thick mucus and not being able to gain weight
Artiquety
in
Oesophageal & Gastric Cancer
8 days ago
Newly Diagnosed
Hi. Thanks for allowing me into the forum. I was diagnosed on Monday that I have 2 anterior tumours. Gleason score of 7 (3 + 4) T3a. No cancer seen in the Lymph nodes. It is breaking into the outer casing. I have a bone scan this afternoon. Assuming my bone scan is all clear, what will be my options
Hi. Thanks for allowing me into the forum. I was diagnosed on Monday that I have 2 anterior tumours. Gleason score of 7 (3 + 4) T3a. No cancer seen in the Lymph nodes. It is breaking into the outer casing. I have a bone scan this afternoon. Assuming my bone scan is all clear, what will be my options
Tulile
in
Prostate Cancer Network
8 days ago
HGS stage 3b
Has anyone been through similar. I was diagnosed in May 2020 after total hysterectomy bue due to bladder injury in surgery was unable to start chemotherapy due to risk of sepsis. I had 1st reoccurance in sept 2021 and finished carbo/taxol in jan 2022. I have been on Lynparza for 2 years just finished
Has anyone been through similar. I was diagnosed in May 2020 after total hysterectomy bue due to bladder injury in surgery was unable to start chemotherapy due to risk of sepsis. I had 1st reoccurance in sept 2021 and finished carbo/taxol in jan 2022. I have been on Lynparza for 2 years just finished
0151tmac69
in
My Ovacome
8 days ago
Epstein's Opinion vs New Uro's
Hi folks, I had Epstein give me a second opinion on my last biopsy, which was at the end of 2022. The original pathology report stated the 3+3 diagnosis was upgraded to 3+4, but didn't give any info about percentages of G4 cancer. Epstein cleared that up stating there was less than 5% G4, but there
Hi folks, I had Epstein give me a second opinion on my last biopsy, which was at the end of 2022. The original pathology report stated the 3+3 diagnosis was upgraded to 3+4, but didn't give any info about percentages of G4 cancer. Epstein cleared that up stating there was less than 5% G4, but there
PTvsPC
in
Prostate Cancer Network
9 days ago
Success stories
Hello I was diagnosed with Gleason 3+4 in January and had surgery - clear margins and clear lymph nodes but worried and have a lot of anxiety about recurrence. Any success stories out there? Please share as I am so scared of my first PSA test in a few weeks. Thanks
Hello I was diagnosed with Gleason 3+4 in January and had surgery - clear margins and clear lymph nodes but worried and have a lot of anxiety about recurrence. Any success stories out there? Please share as I am so scared of my first PSA test in a few weeks. Thanks
Granolaberry
in
Prostate Cancer Network
9 days ago
Newly Diagnosed Prostate Cancer
Hi, I am new here. I came to this site because my husband was just diagnosed with prostate cancer last week. MRI PI RAS 5 with an extracapsular extension, cores 4/12 positive, Gleason 7 (4+3), and PSA 4.8 (PSA 2.2 in 2022). No involvements with lymph nodes and bones on MRI. All of these seem to put
Hi, I am new here. I came to this site because my husband was just diagnosed with prostate cancer last week. MRI PI RAS 5 with an extracapsular extension, cores 4/12 positive, Gleason 7 (4+3), and PSA 4.8 (PSA 2.2 in 2022). No involvements with lymph nodes and bones on MRI. All of these seem to put
kiyo
in
Advanced Prostate Cancer
9 days ago
Mistery therapy: Gastrin-releasing peptide receptors s target for PCa
I will have to dig deeper to find the 4 clinical trials mentioned, but here is the text "Each tumor has its own distinctive molecular identity. Treatment, therefore, should be tailored to this unique cancer phenotype. Theragnostics uses the same compound for targeted imaging and treatment, radiolabeled
I will have to dig deeper to find the 4 clinical trials mentioned, but here is the text "Each tumor has its own distinctive molecular identity. Treatment, therefore, should be tailored to this unique cancer phenotype. Theragnostics uses the same compound for targeted imaging and treatment, radiolabeled
Maxone73
in
Advanced Prostate Cancer
10 days ago
Prostate Cancer Stems Cells/ what kills them?
I have done my duty. Radiation to my lymph nodes, and 24 months of Lupron and Erleada. Now I wait!!!!! yikes. Is there any way to kill Prostate Cancer stem cells? I have read a little about possible advances in killing cancer stem cells. What about prostate cancer stem cells. Im hoping to find
I have done my duty. Radiation to my lymph nodes, and 24 months of Lupron and Erleada. Now I wait!!!!! yikes. Is there any way to kill Prostate Cancer stem cells? I have read a little about possible advances in killing cancer stem cells. What about prostate cancer stem cells. Im hoping to find
icanwintwice
in
Advanced Prostate Cancer
11 days ago
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