Experiences with

Vincristine

O (Obinutuzumab) CHOP (DOXORUBICIN (Adiamycin), vinCristine (Oncovin), cyclophosphamide (Cytoxan), Prednisone) plus Neulasta ejections. April-May 2024 3 cycles of O CHOP until BMT in Later June. BMT donor 10/10 match June 17.

https://www.jic.ac.uk/blog/vinblastine-and-vincristine-life-saving-drugs-from-a-periwinkle/ It's also known for its cardiotoxicity. :( Neil

We have been given some info about PCV combination of the chemotherapy drugs procarbazine, lomustine (CCNU) and vincristine as a possible treatment but Mums consultant said the side effects are pretty crappy and also second line chemo isn’t always as effective.

Butyrate has also been shown to enhance the effects of anticancer drug therapy including vincristine, celecoxib, cisplatin, and etoposide via its HDI activity, increasing the cytotoxicity of the drugs (Ramos et al., 2004, Kang et al., 2012, Maruyama et al., 2012).

Diagnosed in 2008 with NHL (SLL) her haematologist treated her with 6 cycles of CHOP +R (cyclophosphamide, doxorubicin, vincristine, prednisone + rituximab). This was followed by 9 quarterly treatments of rituximab.

From a 2002 paper [3]: "In this study, we report for the first time that cardiac glycosides (e.g. ouabain and digitoxin) induced resistance of human prostate cancer cells (PC-3) in vitro to tubulin-binding anticancer drugs, such as paclitaxel, colchicine, vincristine and vinblastine." *

Obinutuzunab, Cyclophosphamide, Doxorubicin, Vincristine. Am scheduled for infusion 1\29,30,31. Doctor said that this cocktail has 30 years success rate leading up to stem cell transplant. Wondering if anyone has had this and how it went. I know I will lose my hair and it will grow back.

Anybody seen any results using these drugs to help Prostate Cancer?

Since then we tried several things and the only thing that worked for me was either dex or Vincristine, I opted for Vincristine as I was young, it gave me great results and I looked normal without the dex side effects. We then decided to stop having Vincristine as I was on it every second month.

was in a published paper called Medication-induced exacerbation of neuropathy in Charcot Marie Tooth Disease link http://cmt.org.uk/wp-content/uploads/2015/04/NeuroMeds.pdf Proposed list of medications of concern to patients with CMT Definite high risk (including asymptomatic CMT) Vinca alkaloids (vincristine

The have started her in Vincristine. Has anyone had success with this ? Need some ideas please

MSU switches Izzie to the Atopica brand of chlorosporine at 25mg twice per day, ups her dosage of prednisolone to 10mg per day, puts her on some gastroprotectants and gives her an injection of Vincristine.

. : It has been announced previously that anti-tropomyosin drugs in combination with anti-mitotic drugs boost the cancer-killing ability of a drug such as vincristine 20-fold in vitro against neuroblastoma cancer cells.

[/i] http://www.cll-nhl.com/2014/09/immunotherapy-for-indolent-low-grade.html The following drugs that should be familiar to us get specific mention: Bendamustine, Idelalisib, Iibrutinib, Revlimid, Rituximab and Vincristine.

(Vincristine and doxorubicin are used to treat Richter's Transformation and other cancers.)

(So, she will continue with CVP-R, minus the Vincristine.) As a result he says we are no longer treating to cure, but to relieve symptoms and get "another good year or two".

Development of rituximab (Rituxan)-containing intensive chemotherapy regimens and chemo-immunotherapy regimens (eg, R-HyperCVAD [rituximab plus hyperfractionated cyclophosphamide, doxorubicin, vincristine, and dexamethasone] or OFAR [oxaliplatin (Eloxatin), fludarabine, and ara-C]) have improved response

Medications known to cause peripheral neuropathy, include several AIDS drugs (DDC and DDI), antibiotics (metronidazole, an antibiotic used for Crohn's disease, isoniazid used for TB), gold compounds (used for rheumatoid arthritis), some chemotherapy drugs (such as vincristine and others) and many others