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not feeling good
I am a black American man with Stage IV disease. I have had pelvic floor, nodes and seminal vesicle External beam radiation then Brachytherapy radiation to prostate. I am 1 1/2 years into ADT ( lupron, abiraterone, prednisone). I feel bloated and uncomfortable in the evenings especially (gluten-free
I am a black American man with Stage IV disease. I have had pelvic floor, nodes and seminal vesicle External beam radiation then Brachytherapy radiation to prostate. I am 1 1/2 years into ADT ( lupron, abiraterone, prednisone). I feel bloated and uncomfortable in the evenings especially (gluten-free
JayJinxed8112
in
Advanced Prostate Cancer
1 year ago
Are there options past Pluvicto?
Hi! First, thanks to all of you for sharing and caring for each other in this forum. It means so much, to so many of us! I am on this forum on behalf of my father. He was diagnosed last year, and over the last 15 months he has endured ADT, Zytiga, Docetaxel (6 cycles), Cabazitaxel (four cycles before
Hi! First, thanks to all of you for sharing and caring for each other in this forum. It means so much, to so many of us! I am on this forum on behalf of my father. He was diagnosed last year, and over the last 15 months he has endured ADT, Zytiga, Docetaxel (6 cycles), Cabazitaxel (four cycles before
Marit85
in
Advanced Prostate Cancer
1 year ago
Ginseng and Testosterone
Does anyone know of any solid clinical proof that Ginseng does promotes the rise of testosterone and whether it is safe to take whilst being treated for PC. I know whilst on adt it helps with overall fatigue but would that be defeating the object of the pc cells feeding on more produced testosterone,
Does anyone know of any solid clinical proof that Ginseng does promotes the rise of testosterone and whether it is safe to take whilst being treated for PC. I know whilst on adt it helps with overall fatigue but would that be defeating the object of the pc cells feeding on more produced testosterone,
Knittingque
in
Advanced Prostate Cancer
1 year ago
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ADT Hot Flashes
I've been on ADT since Feb, 2023 maintaining everything ok, play Water Polo 4x a week for 2 hours - master water polo team and lift weights - but in the last few weeks the hot flashes are crazy strong. One minute I'm doing great and then 30 seconds later sweating bullets. I work from home thank god,
I've been on ADT since Feb, 2023 maintaining everything ok, play Water Polo 4x a week for 2 hours - master water polo team and lift weights - but in the last few weeks the hot flashes are crazy strong. One minute I'm doing great and then 30 seconds later sweating bullets. I work from home thank god,
plato123
in
Advanced Prostate Cancer
1 year ago
ndt dosage advice after results please
I have been taking NDT for 8 weeks and had my blood test yesterday. Results are attached. I initially felt much better but in the last couple of weeks I have felt the fatigue creep back in a little so was thinking I may need to increase my dose a little following my blood test. I normally take 2 grains
I have been taking NDT for 8 weeks and had my blood test yesterday. Results are attached. I initially felt much better but in the last couple of weeks I have felt the fatigue creep back in a little so was thinking I may need to increase my dose a little following my blood test. I normally take 2 grains
Knackeredandcross
in
Thyroid UK
1 year ago
Dormant or Dead?
I asked my MO early on if ADT kills PC cells or do they simply go dormant? He stated that they go dormant. Since this discussion I have read that ADT starves cancer cells of T and then they die off. So do they die or simply go dormant, or is it a mix of both?
I asked my MO early on if ADT kills PC cells or do they simply go dormant? He stated that they go dormant. Since this discussion I have read that ADT starves cancer cells of T and then they die off. So do they die or simply go dormant, or is it a mix of both?
Gym-rat
in
Advanced Prostate Cancer
1 year ago
Help! Need feedback on Pluvicto recommendation
Quick recap - asymptomatic hubby was diagnosed with StageIVb last summer. No mutations but was already in soft tissue of brain, lungs and bones. Stereotactic radiation last July took care of two brain tumors. He has responded extremely well to triple therapy (Lupron, Zytiga, and Docetaxal). It took
Quick recap - asymptomatic hubby was diagnosed with StageIVb last summer. No mutations but was already in soft tissue of brain, lungs and bones. Stereotactic radiation last July took care of two brain tumors. He has responded extremely well to triple therapy (Lupron, Zytiga, and Docetaxal). It took
Sewinggam
in
Advanced Prostate Cancer
1 year ago
Does Anyone Feel?
I am wondering if its possible to feel as well on thyroid replacement as I did pre hypothyroid. Just for background looking back 4 years ago I felt really fit and healthy,had plenty of energy, was going to the gym. Then the pandemic hit and my gym closed down and went bust. In June 2020 I finally started
I am wondering if its possible to feel as well on thyroid replacement as I did pre hypothyroid. Just for background looking back 4 years ago I felt really fit and healthy,had plenty of energy, was going to the gym. Then the pandemic hit and my gym closed down and went bust. In June 2020 I finally started
Sparklingsunshine
in
Thyroid UK
1 year ago
Which ndt is the best in combination with levothyroxine?
Hi, I have noticed that levothyroxine dosages that exceed 100 mcg give me unpleasant side effects. I need 125 - 137 daily t4 and would like to add the difference from 100 mcg in ndt. Also I take aprox 18 mcg t3 slow release split in 3 doses. I tried to add 1/2 grain of erfa and thyroid-s but I feel
Hi, I have noticed that levothyroxine dosages that exceed 100 mcg give me unpleasant side effects. I need 125 - 137 daily t4 and would like to add the difference from 100 mcg in ndt. Also I take aprox 18 mcg t3 slow release split in 3 doses. I tried to add 1/2 grain of erfa and thyroid-s but I feel
adin
in
Thyroid UK
1 year ago
Switching from T4-T3 combination to NDT
I’m currently on T4 (150 mcg)+T3 (30mcg) combination (taking 1.5 Novothyral; 1 Novothyral has 100mcg T4 and 20mcg T3, I hope my math is correct), but decided to try Thyroid S NDT. Any suggestions which dose to use? And should I split it during the day, the way I do with the combination therapy? What
I’m currently on T4 (150 mcg)+T3 (30mcg) combination (taking 1.5 Novothyral; 1 Novothyral has 100mcg T4 and 20mcg T3, I hope my math is correct), but decided to try Thyroid S NDT. Any suggestions which dose to use? And should I split it during the day, the way I do with the combination therapy? What
Alex_p
in
Thyroid UK
1 year ago
Severe cramps and ADT
I have led a very active life running long distance races and long bike rides. So I’m used to getting some moderate leg cramps after a long workout. I’ve been able to minimize them by taking electrolyte drinks. Once I started ADT (Lupron, abiraterone, prednisone), I started getting severe leg cramps
I have led a very active life running long distance races and long bike rides. So I’m used to getting some moderate leg cramps after a long workout. I’ve been able to minimize them by taking electrolyte drinks. Once I started ADT (Lupron, abiraterone, prednisone), I started getting severe leg cramps
Gym-rat
in
Advanced Prostate Cancer
1 year ago
Options for Recurrent PCa w/ RT Initial Therapy
Looking for options with intent to [u]cure[/u] if recurrence is limited to prostate only, pending PET-PSMA. Have read about these options: Prostatectomy/Brachytherapy/Cystoprostatectomy/Cryotherapy Anybody have any knowledge or studies that might suggest a direction? Still hoping for the possibility
Looking for options with intent to [u]cure[/u] if recurrence is limited to prostate only, pending PET-PSMA. Have read about these options: Prostatectomy/Brachytherapy/Cystoprostatectomy/Cryotherapy Anybody have any knowledge or studies that might suggest a direction? Still hoping for the possibility
Researcher50
in
Advanced Prostate Cancer
1 year ago
Why disparity in NDT prices ?
I have been fortunate to recieve many kind recommendations for NDT suppliers, and I am astonished at the diferences in cost of each different products !
I have been fortunate to recieve many kind recommendations for NDT suppliers, and I am astonished at the diferences in cost of each different products !
Yorkshireman356
in
Thyroid UK
1 year ago
Thyroid S ?
Any thoughts on this NDT ? It is very cheap compared to other !
Any thoughts on this NDT ? It is very cheap compared to other !
Yorkshireman356
in
Thyroid UK
1 year ago
Supraphysiological Androgens [SPA] Promote Tumor Suppressive Activity of the AR Through cMYC Repression and Recruitment of the DREAM Complex
New study [1]. I have struggled to understand how Denmeade’s BAT (Bipolar Androgen Therapy) depends on supraphysiological levels of androgen (testosterone = ~2,000 ng/dL), considering that Morgentaler’s saturation model has it that androgen receptors [ARs] have all the testosterone they can use at
New study [1]. I have struggled to understand how Denmeade’s BAT (Bipolar Androgen Therapy) depends on supraphysiological levels of androgen (testosterone = ~2,000 ng/dL), considering that Morgentaler’s saturation model has it that androgen receptors [ARs] have all the testosterone they can use at
pca2004
in
Fight Prostate Cancer
1 year ago
Should I have RT, given the possible permanent SEs
I had an RP in 2015, and was clear until diagnosed in Dec 2022 with metastatic Pc, PSA .61. Started Bicalutamide and have had 2 Zoladex injections . PSA is now.01. My OC now wants to start RT with 33 sessions. I want to know if I can avoid RT altogether, because of the damage and side effects that might
I had an RP in 2015, and was clear until diagnosed in Dec 2022 with metastatic Pc, PSA .61. Started Bicalutamide and have had 2 Zoladex injections . PSA is now.01. My OC now wants to start RT with 33 sessions. I want to know if I can avoid RT altogether, because of the damage and side effects that might
Dazzaboy
in
Advanced Prostate Cancer
1 year ago
Another Cialis Question
I think this is in my profile, but: Gleason 8 (4+4), RP done 5/2022 showed ECE and a positive lymph node. PSA rising by 6 weeks post-op. ADT started 8/2022 and he had radiation 9-11/2022. After some ups and downs with his liver values, he is currently taking Orgovyx, Abiraterone, and Prednisone. PSA
I think this is in my profile, but: Gleason 8 (4+4), RP done 5/2022 showed ECE and a positive lymph node. PSA rising by 6 weeks post-op. ADT started 8/2022 and he had radiation 9-11/2022. After some ups and downs with his liver values, he is currently taking Orgovyx, Abiraterone, and Prednisone. PSA
Tigger2022
in
Advanced Prostate Cancer
1 year ago
Obtaining NDT ?
HI, I have a problem with oedema in both my legs and I think it's related to my thyroid !I have only had my antibodies checked once in ten years and they were off the charts 1000 + ! I am currently taking 125mg Levothyroxine but worried this is the correct treatment as I only get checked for my TSH
HI, I have a problem with oedema in both my legs and I think it's related to my thyroid !I have only had my antibodies checked once in ten years and they were off the charts 1000 + ! I am currently taking 125mg Levothyroxine but worried this is the correct treatment as I only get checked for my TSH
Yorkshireman356
in
Thyroid UK
1 year ago
Androgens & colorectal cancer
Interesting new Swedish study below [1]. “To assess whether androgens play a role in explaining the sex related differences in the incidence of colorectal cancer (CRC).” According to the American Cancer Society: “Overall, the lifetime risk of developing colorectal cancer is about 1 in 23 for men
Interesting new Swedish study below [1]. “To assess whether androgens play a role in explaining the sex related differences in the incidence of colorectal cancer (CRC).” According to the American Cancer Society: “Overall, the lifetime risk of developing colorectal cancer is about 1 in 23 for men
pca2004
in
Fight Prostate Cancer
1 year ago
Struggling with ADT lack of libido
Hi everyone. I'm 48 and last June was diagnosed rare very aggressive stage IV cancer (salivary ducts), spread already to bones and lungs. I hope I can post here questions about ADT since there is not forum for my cancer type (too rare). I got 9 cycles of chemo, and after a break of two months and some
Hi everyone. I'm 48 and last June was diagnosed rare very aggressive stage IV cancer (salivary ducts), spread already to bones and lungs. I hope I can post here questions about ADT since there is not forum for my cancer type (too rare). I got 9 cycles of chemo, and after a break of two months and some
scale73
in
Advanced Prostate Cancer
1 year ago
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