Experiences with

Prostate disease

PRACTICE GUIDANCE Primary biliary cholangitis: 2021 practice guidance update from the American Association for the Study of Liver Diseases Lindor, Keith D.*,1; Bowlus, Christopher L.2; Boyer, James3; Levy, Cynthia4; Mayo, Marlyn5 Author Information Hepatology 75(4):p 1012-1013, April 2022. | DOI

Hi all, I've been enjoying following many of your stories and it has helped me prepare for this journey. Thanks to everyone who graciously shares and responds here. My original post and bio tell my story, but I have to add this new information from my mpMRI this morning. Here it is: IMPRESSION:

Rouge clone radiation on 10/31/23 has PSA from 4.83 on 11/20/23 to 0.85 on 12/18. HOWEVER, PSA up to 1.48 on 1/29/24 then 2.48 on 2/15/24. Waiting MO response but anticipate PET scan, radiation and/or switch to Xtandi. Was hoping to ride the Zytiga therapy as long as possible but I may be there now.

Just completed my checkup after ending ADT in May. My doctor was looking to schedule a PSMA scan to build a baseline. Since I was diagnosed Gleason 9 there is a chance that cancer could reoccur without expressing PSA. ---- well my oncologist talked directly with the insurance advisors (I consulted a

morning, can anyone advice me about hepatic Encephalopathy ? I have stage 4 liver desease and was feeling so confused last night with things like time and thinking lights were off but were on is this the start of it? Last time I was like this was last march when I had my diagnoses, I take lactose which

This looks promising. The trial enrolled 18 patients who were on androgen deprivation therapy but had not received prior AR pathway inhibitors; some had received chemotherapy in the hormone-sensitive setting. Patients were treated with escalating doses of Masofaniten (EPI-7386), up to 600 mg twice daily

My sensation is that it is too early to say ho well it works, but SE look pretty harsh! The trial enrolled 181 men with mCRPC who had previously received one androgen receptor pathway inhibitor. Participants were randomized to receive vobramitamab at either 2.0 mg/kg or 2.7 mg/kg every four weeks. The

Ok, I am not so impressed with this new molecule, but here it is. BMS-986365 is designed to inhibit androgen receptor (AR) activity through a dual mechanism of degrading the receptor and blocking its function, aiming to overcome resistance to standard AR pathway inhibitors like enzalutamide and abiraterone

In this randomized controlled trial, lixisenatide reduced motor disability progression in Parkinson’s patients. 2. Individuals in the lixisenatide group experienced greater gastrointestinal side effects rates than individuals in the placebo group. Evidence Rating Level: 1 (Excellent) https:/

In September last year my PSA was 0.06. Three months later PSA was 0.09. I asked my doctor if xtandi was failing. He told me not necessarily, once your PSA reached its lowest point, it tends to go up and down before it settles down. He told me they would check my PSA in six weeks, six weeks later

Father’s current Age: 78 At age 70, Diagnosed with Pca in 2015 after seeing initial PSA as ~ 270. 2015 - 2019 - BICALUTAMIDE - Failed 2019 - 2020 - Radiation- Ineffective 2020 Oct - 2021 October - Zytiga (Aberiterone) - Failed - PSA 98 2021 Dec - 2022 Apr - Docetaxel- Ineffective - PSA 120 2022

https://www.youtube.com/watch?v=S_JvSVlOdZ8 https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(24)00440-6/abstract Some phase 2 early results : adding LuPSMA to (ADT + docetaxel) has generated a strong result in men with "newly diagnosed high-volume mHSPC" April 2020 the trial started

Mr. Spouse 21 is starting a Docetaxel rechallenge next week--3 rounds then another PMSA-PET scan. If you did a Docetaxel rechallenge as well, can you compare your early experiences with the rechallenge in terms of side effects and effectiveness and where you are now? He developed neuropathy despite using

I lake low volume Metastatic PCA. Found in 4 lymph nodes / couple spots on pelvic bones . I m on 1m mgs Abby 5 mgs Pred, had a shot of Fermigon and start Lupron next week , Radiation starting end of month . let me know if any suggestions other than a positive attitude? Right now I exercise regularly

I had PSA of 250 Gleason 9/10 in 2019 Mar. Was under ADT regime from Jun 19 followed by IMRT in Nov 19. It was 39 sessions of 78 Gy to prostrate, prostrate bed, pelvic nodes. Later in Sep 22 PSA started to rise indicating BCR. In Jan 22 underwent Orchidectomy followed by Nubeqa for 19 months now. I've

and path I just got my 2nd PSA result today and it showed my level at 3.0...My prosectomy was done 3/21/24 and surgeon took lymp nodes, floor tissue, margins, etc and path report showed pristine results. I also had PSMA and MRI with contrast pre-surgery and both scans showed no spread and fully contained

Based on the outstanding response to yesterday's video with Don (the retired Canadian Mountie), I will be happy to record more interviews with the guys in our prostate cancer community. Your experience could help others navigate their paths and provide invaluable insights into the everyday realities

Has anyone had a Pylarify (PSMA) pet scan showing no prostate cancer spread but knew that you had some metastasis in at least one lymph node (seen in an older scan and confirmed by biopsy). I know that there are people who are PSMA negative...not sure if my husband is one. He has had a prostatectomy,

"The drug, JHU083, is a type of molecule called a prodrug that cells inside the body convert into an active drug. Specifically, JHU083 can only be turned into its active, glutamine-blocking form inside the tumor, preventing it from causing harmful side effects elsewhere in the body. " We all know that

Hi, I am new to this forum and have been advised to seek info and advice here from The Thyroid UK forum. I recently discovered I was hyperthyroid with positive thyroid antibody results indicative of autoimmune thyroid disease following blood tests as feeling unwell with multiple symptoms. I was advised