Experiences with

Pegasys

Has anyone, with Hashimoto's, had any adverse side effects while using Pegasys? Ever since I was switched from Hydroxyurea to Pegasys, my body has had an explosion of pain, ranging from headaches to GERD to sinus issues and beyond.

I recently changed my Pegasys dose from 45mcg every four weeks to 90mcg every eight weeks, because of the current shortage.

https://www.ema.europa.eu/en/medicines/human/variation/pegasys It looks like Pegasys has been approved by the European EMA for treating PV and ET. Although Pegasys has been used to treat these diseases for some time, it was previously off-label.

I’ve not had any side effects to the Pegasys. I feel great on the Pegasys, and all my ET related symptoms are gone, including the one that was most persistent - burning feet.

I have been on Pegasys for the two years since my diagnosis of PV at age 59, initially on a weekly dose of 45 mcg and for the last year on 67.5 a fortnight.

Just had 3 monthly telephone call with consultant. I tested positive for Covid two days ago, she recommended I take the anti viral. My bloods all stable. She then said oh you will need your pegysys. I said yes thinking i would have to change due to shortage. Hospital pharmacy are delivering it tomorrow

Hi can anyone tell me the difference between hydrea low dose to interferon as I am possibly switching from pegasys interferon to hydrea in the next week or so because of shortage thanks all

I just had to change from Pegasys due to too many side effects, and was put on Jakafi. My question is does 15 mg. twice a day for a woman that is 110 lbs. seem like a lot? From what I read it seems so to me.

Has anyone had this happen while on Pegasys?

I gather this can be Pegasys induced? I also have a low Basophil reading of 0.1 (UK readings). I certainly have most of the symptoms! Has anyone experienced this? I have an appointment with my Team 11th November.

I've been trying to live healthier and lose weight, so I started looking into minimizing glucose spikes. I came across a suggestion to take one tablespoon of vinegar before the starchiest meal of the day. However, I read that citric acid prevents platelets from sticking together, which seems to be exactly

Met with hematologist today here in Houston and I am pleased to report that it was a fairly good one. 41 yo male CALR mutation - on Pegasys 135 mcg weekly and currently weening off of hydroxyurea @ 500 mg (1 pill) every other day.

Hi, I am 71, have had PV (exon 12) for about 4 years, been on pegasys for 3 years. Presently apparently in CHR, with maintenance dose of pegasys 45 mcg every other week. Generally it has been going well.

hi all, I’m about to start the next stage of my treatment journey, 45mg Pegasys fortnightly. I’ve picked up the meds and just waiting for my remaining blood tests to come back before I start.

Hi, just wanted to share after about a year being on Pegasys 45 mcg fortnightly my JAK2 VAF dropped from 31% at diagnosis to 26% now.Always happy to see progress. All blood counts in good range except elevated Potassium 5.8 mmol/L which I am not sure why as all previous tests were in range.

Has anyone else had their skin turn into rough, dry, chicken skin on large parts of their bodies after taking Pegasys? Mine started out with itchiness, and now the skin itself is weird. I've used tons of lotion, including Sarna. I have also taken Beta Alanine orally. Problem is growing worse.

Hi everyone This is the first year for having the flu jab and Pegasys asI started Peg in March. I’m now on Peg 90mg every 2 weeks because of the shortage. I do have a dry mouth which started 4 months after starting Peg but doesn’t concern my haematologist. Otherwise fine.

There is a phone number for questions on this: "Please direct any clinical product questions to pharma& by phone at (888) 814-7PEG (7734)" https://www.gene.com/patients/medicines/pegasys I called it and it seems to service both UK and USA.

I have been on interferon (Pegasys) for Jak2 ET since March of 2021. In 2021 I also noted that I was breathing heavily with minor exertion (walking). As I was a smoker I assumed I had done this to myself.

Any experiencers using pegasys in addition to post covid? Were there any changes our side effects? Greetings Paul (Et + postcovid)