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The Use of Low Dose Estradiol to Ameliorate the Effects of ADT on Bone Mass Density
I have been conducting a long-term n of 1 trial since January 23, 2021 using lose dose estradiol (E2) gel to counteract the effects of androgen deprivation therapy (ADT) on bone mass density (BMD). I believe that I now have sufficient data to report that low dose transdermal E2, along with exercise and
I have been conducting a long-term n of 1 trial since January 23, 2021 using lose dose estradiol (E2) gel to counteract the effects of androgen deprivation therapy (ADT) on bone mass density (BMD). I believe that I now have sufficient data to report that low dose transdermal E2, along with exercise and
PhilipSZacarias
in
Advanced Prostate Cancer
1 year ago
An Important thing to know if considering Estrogen Therapy.
My experience using estrogen as my only form of ADT has been positive. However, when my psa started rising and I began to feel pain in my spine and pelvis my MO put me on Zometa (bone drug IV every 3 mo). Was it necessary? I have no idea. I now get mildly sick for about 36 hours after the infusion
My experience using estrogen as my only form of ADT has been positive. However, when my psa started rising and I began to feel pain in my spine and pelvis my MO put me on Zometa (bone drug IV every 3 mo). Was it necessary? I have no idea. I now get mildly sick for about 36 hours after the infusion
No_stone_unturned
in
Advanced Prostate Cancer
1 year ago
quick update
just spoke with my urology nurse consultant, my PSA is now 0.05, looks like the hormone treatment is working, looking like radiotherapy will start April/ May, I’ve got a personal trainer sorted out and a diet plan, and the effects of the hormone injection have eased, so I’m feeling positive Regards
just spoke with my urology nurse consultant, my PSA is now 0.05, looks like the hormone treatment is working, looking like radiotherapy will start April/ May, I’ve got a personal trainer sorted out and a diet plan, and the effects of the hormone injection have eased, so I’m feeling positive Regards
ukpete
in
Prostate Cancer Network
1 year ago
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Bone Density - Dexa
I read somewhere that in the pre-Lupron days when DES (Diethylstilbestrol) was commonly used, bone loss was not a major issue. My 19-year history falls into three phases: i) continuous testosterone [T] ii) alternating 3-month periods of ADT & T iii) my version of BAT (LongBAT) - a single T injection
I read somewhere that in the pre-Lupron days when DES (Diethylstilbestrol) was commonly used, bone loss was not a major issue. My 19-year history falls into three phases: i) continuous testosterone [T] ii) alternating 3-month periods of ADT & T iii) my version of BAT (LongBAT) - a single T injection
pjoshea13
in
Fight Prostate Cancer
1 year ago
PSA keeps rising
My PCa timeline:April 2022 - DX with PCa, Gleason 3+4, PSA 18 Jun 2022 - PSA 28, given 3 month shot of lupron Aug 2022 - 20 sessions of IGRT Sep 2022 - PSA 0.56 Dec 2022 - PSA 1.6 Feb 2023 - PSA 5.3 Mar 4, 2023 - PSMA PET scan shows a single spot ("moderately tracer-avid focus at 6th rib ... suspicious
My PCa timeline:April 2022 - DX with PCa, Gleason 3+4, PSA 18 Jun 2022 - PSA 28, given 3 month shot of lupron Aug 2022 - 20 sessions of IGRT Sep 2022 - PSA 0.56 Dec 2022 - PSA 1.6 Feb 2023 - PSA 5.3 Mar 4, 2023 - PSMA PET scan shows a single spot ("moderately tracer-avid focus at 6th rib ... suspicious
John347
in
Advanced Prostate Cancer
1 year ago
Stopping medication
Hi everyone, I am really desperate with what to do next as nothing works for me. I was finally getting NDT and had so much expectation from it. I was fine for few days and then my stomach started to hurt that bad that I couldn't bed down. I email my specialist and ask what to do . He said to stop and
Hi everyone, I am really desperate with what to do next as nothing works for me. I was finally getting NDT and had so much expectation from it. I was fine for few days and then my stomach started to hurt that bad that I couldn't bed down. I email my specialist and ask what to do . He said to stop and
Mackanzie0
in
Thyroid UK
1 year ago
Next Move?
Briefly, I had Radical Prostatectomy in February of 2018, ADT with Salvage Radiation ending in September of 2019 and undetectable PSA until August of 2022 when it increased to .09, then .12 in October, and .22 in December. Finally, .34 in March 2023. I just received this message from my Oncologist
Briefly, I had Radical Prostatectomy in February of 2018, ADT with Salvage Radiation ending in September of 2019 and undetectable PSA until August of 2022 when it increased to .09, then .12 in October, and .22 in December. Finally, .34 in March 2023. I just received this message from my Oncologist
Imp4t
in
Advanced Prostate Cancer
1 year ago
Energy and weight
Really struggling with fatigue and this weight. Up 20 lb..I think its a mental block..hard to get to the gym even though that is the answer. Ran 1,100 miles in 2019, backed off due to foot nerve operation..now 20 minutes in gym and I am exhausted. Just a couple months post radiation after failed surgery
Really struggling with fatigue and this weight. Up 20 lb..I think its a mental block..hard to get to the gym even though that is the answer. Ran 1,100 miles in 2019, backed off due to foot nerve operation..now 20 minutes in gym and I am exhausted. Just a couple months post radiation after failed surgery
runtrails
in
Advanced Prostate Cancer
1 year ago
Symptoms when ADT no longer works?
Hello, everyone! I have begun year two of stage 4 metastatic prostate cancer and I have BRCA2. Taking abiraterone + prednisone daily and Lupron shots twice a year. I am doing my best to live one day at a time but wonder what things will look like when the cancer becomes resistant. Does anybody know?
Hello, everyone! I have begun year two of stage 4 metastatic prostate cancer and I have BRCA2. Taking abiraterone + prednisone daily and Lupron shots twice a year. I am doing my best to live one day at a time but wonder what things will look like when the cancer becomes resistant. Does anybody know?
SandyBear2023
in
Advanced Prostate Cancer
1 year ago
Bone Health issues re:Bisphosphonnates, etc. ????
I'm back again for further research about the bone density medications, and now wondering about the use of bisphosphonates, denosumab and teriparatide? My PCP is suggesting these, but he's not current with the research about estrogen and testosterone use for PCa care. My backstory is that I'm suffering
I'm back again for further research about the bone density medications, and now wondering about the use of bisphosphonates, denosumab and teriparatide? My PCP is suggesting these, but he's not current with the research about estrogen and testosterone use for PCa care. My backstory is that I'm suffering
ragnar2020
in
Fight Prostate Cancer
1 year ago
Hormonal therapy and pain
Do you have experiences that hormonal therapy (ADT, Erleada etc) cause pain? What kind is it and have you stopped drugs? Or have you had a break and started it again? Or what has helped? My dad has been on ADT and Erleada for couple of months. Everything went fine but now he has quite bad pain ecpecially
Do you have experiences that hormonal therapy (ADT, Erleada etc) cause pain? What kind is it and have you stopped drugs? Or have you had a break and started it again? Or what has helped? My dad has been on ADT and Erleada for couple of months. Everything went fine but now he has quite bad pain ecpecially
Daughter17
in
Advanced Prostate Cancer
2 years ago
NDT blood test timing
Good morning all My understanding is when on NDT you should test 12 hours after your dose. Is that correct? If so at that point is the blood test more realistic as an indication of how well you are doing? I ask this because at my last one I was only a third way through the range of T3.
Good morning all My understanding is when on NDT you should test 12 hours after your dose. Is that correct? If so at that point is the blood test more realistic as an indication of how well you are doing? I ask this because at my last one I was only a third way through the range of T3.
Jodypody
in
Thyroid UK
2 years ago
proving hypothyroidism
is this enough to prove hypothyroidism to nhs like a GP? My t4 was 16.9 with no treatment a few years ago but I was still having hypothyroid symptoms so started on NDT. It’s got worse in last year and a half and this are my recent results whilst on 160 of NDT- if I wasn’t on it, my t4 would be too low
is this enough to prove hypothyroidism to nhs like a GP? My t4 was 16.9 with no treatment a few years ago but I was still having hypothyroid symptoms so started on NDT. It’s got worse in last year and a half and this are my recent results whilst on 160 of NDT- if I wasn’t on it, my t4 would be too low
Kitkat1982
in
Thyroid UK
2 years ago
Stage 4 ~ Now Losing Blood Somewhere
Hi, my husband was diagnosed stage 4 with lymph node and bladder neck margins involvement 3/2018. He has done chemo, radiation, and hormone therapy over the past 5 years. His PSA increased quickly starting in October 2022 and by December it was 27. Hormone therapy isn’t working as before, it appears
Hi, my husband was diagnosed stage 4 with lymph node and bladder neck margins involvement 3/2018. He has done chemo, radiation, and hormone therapy over the past 5 years. His PSA increased quickly starting in October 2022 and by December it was 27. Hormone therapy isn’t working as before, it appears
drb1966
in
Advanced Prostate Cancer
2 years ago
Testosterone Replacement Therapy
Testosterone level seems to have plateaued at 250 post 2018-19 IMRT, ADT and brachyboost; was never more than 270 pre-treatment. Criteria for starting/stopping TRT? What are its pros and cons? Responses to it from men here? Many thanks, EdinBaltimore
Testosterone level seems to have plateaued at 250 post 2018-19 IMRT, ADT and brachyboost; was never more than 270 pre-treatment. Criteria for starting/stopping TRT? What are its pros and cons? Responses to it from men here? Many thanks, EdinBaltimore
EdinBmore
in
Prostate Cancer And Gay Men
2 years ago
Testosterone Replacement Therapy
Testosterone level seems to have plateaued at 250 post 2018-19 IMRT, ADT and brachyboost; was never more than 270 pre-treatment. Criteria for starting/stopping TRT? What are its pros and cons? Responses to it from men here? Many thanks, EdinBaltimore
Testosterone level seems to have plateaued at 250 post 2018-19 IMRT, ADT and brachyboost; was never more than 270 pre-treatment. Criteria for starting/stopping TRT? What are its pros and cons? Responses to it from men here? Many thanks, EdinBaltimore
EdinBmore
in
Advanced Prostate Cancer
2 years ago
Incontinence after RP and ADT
I had a RO approximately 2 1/2 years ago with a recurrence 12 months later. I have had 37 sessions of radiotherapy and am in month 16 of 18 hormone therapy in the UK. My incontinence seemed to solve itself around 12 months after RP but never fully. In the past 12 months I still suffer from minor involuntary
I had a RO approximately 2 1/2 years ago with a recurrence 12 months later. I have had 37 sessions of radiotherapy and am in month 16 of 18 hormone therapy in the UK. My incontinence seemed to solve itself around 12 months after RP but never fully. In the past 12 months I still suffer from minor involuntary
Runner1957
in
Advanced Prostate Cancer
2 years ago
Minor incontinence
I had a RO approximately 2 1/2 years ago with a recurrence 12 months later. I have had 37 sessions of radiotherapy and am in month 16 of 18 hormone therapy in the UK. My incontinence seemed to solve itself around 12 months after RP but never fully. In the past 12 months I still suffer from minor involuntary
I had a RO approximately 2 1/2 years ago with a recurrence 12 months later. I have had 37 sessions of radiotherapy and am in month 16 of 18 hormone therapy in the UK. My incontinence seemed to solve itself around 12 months after RP but never fully. In the past 12 months I still suffer from minor involuntary
Runner1957
in
Prostate Cancer Network
2 years ago
blood test timings
just a quickie. As I’m on NDT I believe my blood test needs to be 12 hours after my dose. If the blood test came back a third through the range was I right to increase? I did this test on a non training day for worst case scenario.
just a quickie. As I’m on NDT I believe my blood test needs to be 12 hours after my dose. If the blood test came back a third through the range was I right to increase? I did this test on a non training day for worst case scenario.
Jodypody
in
Thyroid UK
2 years ago
Enzalutamide or Darolutamide
Hi, I have advanced metastatic hormone sensitive prostate cancer and as well as my usual three monthly ADT (Lucrin-Depot) injection, I have been offered either Enzalutamide (Xtandi) or Darolutamide (Nubeqa). My PSA is currently below 0.1 due to the Lucrin-Depot. I am a bit nervous at taking additional
Hi, I have advanced metastatic hormone sensitive prostate cancer and as well as my usual three monthly ADT (Lucrin-Depot) injection, I have been offered either Enzalutamide (Xtandi) or Darolutamide (Nubeqa). My PSA is currently below 0.1 due to the Lucrin-Depot. I am a bit nervous at taking additional
x-rays1
in
Advanced Prostate Cancer
2 years ago
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