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Are PSMA negative mets usually castrate resistant?
I had 2 clear PSMA-PETs (at a PSA of 2 & then 4) so Dr. Scholz recommended I get an FDG PET. Low and behold 3 decent sized mets showed up. In my subsequent research it seems like all the published articles describe the PSMA negative mets as being castrate resistant. Zytiga/Lupron was effective before
I had 2 clear PSMA-PETs (at a PSA of 2 & then 4) so Dr. Scholz recommended I get an FDG PET. Low and behold 3 decent sized mets showed up. In my subsequent research it seems like all the published articles describe the PSMA negative mets as being castrate resistant. Zytiga/Lupron was effective before
V10fanatic
in
Advanced Prostate Cancer
1 year ago
3 years Post-VRMAT-RT & ADT
After 3 years my PSA went from
20.3 μg/L
down to <
0.01 μg/L
and Testosterone from
438.04ng/dL
down to
60.52 ng/dL
🙈🙉🙊. As of July 07, 2023. How much longer do I have to wait for a more normal Testosterone Totale. I like my PSA that low but a little bit higher. Recently
After 3 years my PSA went from
20.3 μg/L
down to <
0.01 μg/L
and Testosterone from
438.04ng/dL
down to
60.52 ng/dL
🙈🙉🙊. As of July 07, 2023. How much longer do I have to wait for a more normal Testosterone Totale. I like my PSA that low but a little bit higher. Recently
doc1947g
in
Advanced Prostate Cancer
1 year ago
Hello everyone...
It was in August 2022 that my primary care became alarmed after my PSA returned, and it was 77 plus, that I likewise became alarmed by the fact that I must deal with prostate cancer. As a result, I tried hormone therapy for six months and thought about killing myself if I did not die first from the
It was in August 2022 that my primary care became alarmed after my PSA returned, and it was 77 plus, that I likewise became alarmed by the fact that I must deal with prostate cancer. As a result, I tried hormone therapy for six months and thought about killing myself if I did not die first from the
PC-In-NC
in
Prostate Cancer Network
1 year ago
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3 years Post-VRMAT-RT & ADT
After 3 years my PSA went from
20.3 μg/L
down to
0.02 μg/L
and Testosterone from
438.04ng/dL
down to
60.57 ng/dL
🙈🙉🙊. How much longer do I have to wait for a more normal Testosterone Totale. I like my PSA that low but a little bit higher. Recently I fell and broke
After 3 years my PSA went from
20.3 μg/L
down to
0.02 μg/L
and Testosterone from
438.04ng/dL
down to
60.57 ng/dL
🙈🙉🙊. How much longer do I have to wait for a more normal Testosterone Totale. I like my PSA that low but a little bit higher. Recently I fell and broke
doc1947g
in
Prostate Cancer Network
1 year ago
T3 ONLY - Issues - Please help
Hi all, After many years on Thyroid S, my NHS endo has convinced me to trial t3 only, I have been taking 20 mcg at 6.30am and 10mcg at 10pm. I have been on this dose for approx 4 weeks, and in the last week, I have had the worst outbreak of skin blisters on my forehead and above my lip (this used
Hi all, After many years on Thyroid S, my NHS endo has convinced me to trial t3 only, I have been taking 20 mcg at 6.30am and 10mcg at 10pm. I have been on this dose for approx 4 weeks, and in the last week, I have had the worst outbreak of skin blisters on my forehead and above my lip (this used
dizzy1979
in
Thyroid UK
1 year ago
mCRPC. Total PSA is up from 1.2 to 2.1 in 2 months, but free PSA went to 14% from 5%. Can this be hyperplasia, or in ADT any PSA up is PCa?
mCRPC. Total PSA is up from 1.2 to 2.1 in 2 months, but free PSA went to 14% from 5%. Can this be hyperplasia, or in ADT any PSA up is PCa regardless of free to total PSA ratio ?
mCRPC. Total PSA is up from 1.2 to 2.1 in 2 months, but free PSA went to 14% from 5%. Can this be hyperplasia, or in ADT any PSA up is PCa regardless of free to total PSA ratio ?
Manilo
in
Advanced Prostate Cancer
1 year ago
T level test
Having my first PSA test since IMRT in a few weeks. (last ADT/Lupron was early February. 90 day. Salvage IMRT Radiation ended Early January. Is there a reason my doc didn't order T level test to coincide with the PSA? Seems like you would track increases or Nadirs etc, having them tested the same time
Having my first PSA test since IMRT in a few weeks. (last ADT/Lupron was early February. 90 day. Salvage IMRT Radiation ended Early January. Is there a reason my doc didn't order T level test to coincide with the PSA? Seems like you would track increases or Nadirs etc, having them tested the same time
runtrails
in
Advanced Prostate Cancer
1 year ago
Four Years Results
Hello Everyone, I am reading this forum every day and getting very valuable information. Thank you so much. My hats off to all of you for sharing your experience and knowledge over here and providing much-needed knowledge and compassion to each other. My Case: First diagnosed @ age 71 with PCA in
Hello Everyone, I am reading this forum every day and getting very valuable information. Thank you so much. My hats off to all of you for sharing your experience and knowledge over here and providing much-needed knowledge and compassion to each other. My Case: First diagnosed @ age 71 with PCA in
Pheart2
in
Advanced Prostate Cancer
1 year ago
headaches when moving from NDT to t3 and Levo.
I’ve been on NDT which hasn’t been working anymore as my t4 too low but when I increase my t3 goes too high. I dropped my NDT from 200mg to 40mg and started the t3 2 weeks ago expecting to start Levo a few days after. But my GP surgery is refusing to prescribe it after my private consultant recommended
I’ve been on NDT which hasn’t been working anymore as my t4 too low but when I increase my t3 goes too high. I dropped my NDT from 200mg to 40mg and started the t3 2 weeks ago expecting to start Levo a few days after. But my GP surgery is refusing to prescribe it after my private consultant recommended
Kitkat1982
in
Thyroid UK
1 year ago
Switching from NDT to T3 only - what dose?
Hi, I have been on NDT since 2016, and surely had some relief when starting. Before NDT I really had no life. But as I still have a lot of symptoms (the worse being extreme fatigue), I decided to try to taper off to see if I was over medicated. So this spring I tapered from 2,75 grains to 1,25 grains
Hi, I have been on NDT since 2016, and surely had some relief when starting. Before NDT I really had no life. But as I still have a lot of symptoms (the worse being extreme fatigue), I decided to try to taper off to see if I was over medicated. So this spring I tapered from 2,75 grains to 1,25 grains
Whippets88
in
Thyroid UK
1 year ago
not feeling good
I am a black American man with Stage IV disease. I have had pelvic floor, nodes and seminal vesicle External beam radiation then Brachytherapy radiation to prostate. I am 1 1/2 years into ADT ( lupron, abiraterone, prednisone). I feel bloated and uncomfortable in the evenings especially (gluten-free
I am a black American man with Stage IV disease. I have had pelvic floor, nodes and seminal vesicle External beam radiation then Brachytherapy radiation to prostate. I am 1 1/2 years into ADT ( lupron, abiraterone, prednisone). I feel bloated and uncomfortable in the evenings especially (gluten-free
JayJinxed8112
in
Advanced Prostate Cancer
1 year ago
Are there options past Pluvicto?
Hi! First, thanks to all of you for sharing and caring for each other in this forum. It means so much, to so many of us! I am on this forum on behalf of my father. He was diagnosed last year, and over the last 15 months he has endured ADT, Zytiga, Docetaxel (6 cycles), Cabazitaxel (four cycles before
Hi! First, thanks to all of you for sharing and caring for each other in this forum. It means so much, to so many of us! I am on this forum on behalf of my father. He was diagnosed last year, and over the last 15 months he has endured ADT, Zytiga, Docetaxel (6 cycles), Cabazitaxel (four cycles before
Marit85
in
Advanced Prostate Cancer
1 year ago
Ginseng and Testosterone
Does anyone know of any solid clinical proof that Ginseng does promotes the rise of testosterone and whether it is safe to take whilst being treated for PC. I know whilst on adt it helps with overall fatigue but would that be defeating the object of the pc cells feeding on more produced testosterone,
Does anyone know of any solid clinical proof that Ginseng does promotes the rise of testosterone and whether it is safe to take whilst being treated for PC. I know whilst on adt it helps with overall fatigue but would that be defeating the object of the pc cells feeding on more produced testosterone,
Knittingque
in
Advanced Prostate Cancer
1 year ago
ADT Hot Flashes
I've been on ADT since Feb, 2023 maintaining everything ok, play Water Polo 4x a week for 2 hours - master water polo team and lift weights - but in the last few weeks the hot flashes are crazy strong. One minute I'm doing great and then 30 seconds later sweating bullets. I work from home thank god,
I've been on ADT since Feb, 2023 maintaining everything ok, play Water Polo 4x a week for 2 hours - master water polo team and lift weights - but in the last few weeks the hot flashes are crazy strong. One minute I'm doing great and then 30 seconds later sweating bullets. I work from home thank god,
plato123
in
Advanced Prostate Cancer
1 year ago
ndt dosage advice after results please
I have been taking NDT for 8 weeks and had my blood test yesterday. Results are attached. I initially felt much better but in the last couple of weeks I have felt the fatigue creep back in a little so was thinking I may need to increase my dose a little following my blood test. I normally take 2 grains
I have been taking NDT for 8 weeks and had my blood test yesterday. Results are attached. I initially felt much better but in the last couple of weeks I have felt the fatigue creep back in a little so was thinking I may need to increase my dose a little following my blood test. I normally take 2 grains
Knackeredandcross
in
Thyroid UK
1 year ago
Dormant or Dead?
I asked my MO early on if ADT kills PC cells or do they simply go dormant? He stated that they go dormant. Since this discussion I have read that ADT starves cancer cells of T and then they die off. So do they die or simply go dormant, or is it a mix of both?
I asked my MO early on if ADT kills PC cells or do they simply go dormant? He stated that they go dormant. Since this discussion I have read that ADT starves cancer cells of T and then they die off. So do they die or simply go dormant, or is it a mix of both?
Gym-rat
in
Advanced Prostate Cancer
1 year ago
Help! Need feedback on Pluvicto recommendation
Quick recap - asymptomatic hubby was diagnosed with StageIVb last summer. No mutations but was already in soft tissue of brain, lungs and bones. Stereotactic radiation last July took care of two brain tumors. He has responded extremely well to triple therapy (Lupron, Zytiga, and Docetaxal). It took
Quick recap - asymptomatic hubby was diagnosed with StageIVb last summer. No mutations but was already in soft tissue of brain, lungs and bones. Stereotactic radiation last July took care of two brain tumors. He has responded extremely well to triple therapy (Lupron, Zytiga, and Docetaxal). It took
Sewinggam
in
Advanced Prostate Cancer
1 year ago
Does Anyone Feel?
I am wondering if its possible to feel as well on thyroid replacement as I did pre hypothyroid. Just for background looking back 4 years ago I felt really fit and healthy,had plenty of energy, was going to the gym. Then the pandemic hit and my gym closed down and went bust. In June 2020 I finally started
I am wondering if its possible to feel as well on thyroid replacement as I did pre hypothyroid. Just for background looking back 4 years ago I felt really fit and healthy,had plenty of energy, was going to the gym. Then the pandemic hit and my gym closed down and went bust. In June 2020 I finally started
Sparklingsunshine
in
Thyroid UK
1 year ago
Which ndt is the best in combination with levothyroxine?
Hi, I have noticed that levothyroxine dosages that exceed 100 mcg give me unpleasant side effects. I need 125 - 137 daily t4 and would like to add the difference from 100 mcg in ndt. Also I take aprox 18 mcg t3 slow release split in 3 doses. I tried to add 1/2 grain of erfa and thyroid-s but I feel
Hi, I have noticed that levothyroxine dosages that exceed 100 mcg give me unpleasant side effects. I need 125 - 137 daily t4 and would like to add the difference from 100 mcg in ndt. Also I take aprox 18 mcg t3 slow release split in 3 doses. I tried to add 1/2 grain of erfa and thyroid-s but I feel
adin
in
Thyroid UK
1 year ago
Switching from T4-T3 combination to NDT
I’m currently on T4 (150 mcg)+T3 (30mcg) combination (taking 1.5 Novothyral; 1 Novothyral has 100mcg T4 and 20mcg T3, I hope my math is correct), but decided to try Thyroid S NDT. Any suggestions which dose to use? And should I split it during the day, the way I do with the combination therapy? What
I’m currently on T4 (150 mcg)+T3 (30mcg) combination (taking 1.5 Novothyral; 1 Novothyral has 100mcg T4 and 20mcg T3, I hope my math is correct), but decided to try Thyroid S NDT. Any suggestions which dose to use? And should I split it during the day, the way I do with the combination therapy? What
Alex_p
in
Thyroid UK
1 year ago
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