Experiences with

Lymphocytic leukemia

The link to register for this event can be found here: https://healthtree.org/cll/community/events/mar2025-chronic-lymphocytic-leukemia-history

The link to register for this event can be found here: https://healthtree.org/cll/community/events/mar2025-chronic-lymphocytic-leukemia-history

Limited-duration combination therapies are starting to reshape how chronic lymphocytic leukemia (CLL) will be treated, but which combination is best is still unclear. https://cllsociety.org/2024/12/acalabrutinib-and-obinutuzumab-for-frontline-cll-treatment/

Check it out - https://www.patientpower.info/video/chronic-lymphocytic-leukemia/early-cll-treatment-options-what-to-know?

Abstract report in New England Journal of Medicine Published February 5, 2025 No real new information here and I'm surprised anyone was recruited for this study as the control arm is chemoimmunotherapy and no account appears to have been taken for unmated IGHV or 17p/TP53 as the patients were

https://healthtree.org/cll/community/events/feb2025-chronic-lymphocytic-leukemia-immune-system

[/i] The full paper is a very thorough reference for those wanting to get a better understanding of what is currently understood about chronic lymphocytic leukemia and its treatment.

Financial Assistance for Patients with Chronic Lymphocytic Leukemia (CLL) & Small Lymphocytic Lymphoma (SLL) https://www.lls.org/support-resources/financial-support/co-pay-assistance-program If you are diagnosed with CLL or SLL, you may qualify for The Leukemia & Lymphoma Society's Co-Pay Assistance

In an interesting turn of events, my Mom (75f) just had preliminary cytology results come back indicating B cell related lymphoma or leukemia. They are leaning towards chronic lymphocytic leukemia (CLL)/ small lymphocytic lymphoma but she will need a BMB/additional diagnostics to be sure.

https://www.patientpower.info/chronic-lymphocytic-leukemia/reframing-cll-a-clinical-trial-journey-down-under

[/i] * * * [u]Year in Review: Chronic Leukemia — Top news in 2024 included the first CAR-T approval for CLL, triplet regimens, and more[/u], by Ian Ingram, Managing Editor, MedPage Today December 10, 2024, Last Updated December 11, 2024 Developments in chronic lymphocytic

The association of MRD status as a surrogate end point of clinical outcome in chronic lymphocytic leukemia (CLL) has not been established in the era of targeted agents.

[i][/i] [i]"Oral therapies targeting receptors in a blood cancer called chronic lymphocytic leukemia (CLL) have transformed outcomes with for those with this disease.

Richter transformation involves the evolution of chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL) into an aggressive lymphoma, Tedeschi and colleagues noted in their introduction.

Hi all, I was intrigued by this article: Case Report of Unexpectedly Long Survival of Patient With Chronic Lymphocytic Leukemia: Why Integrative Methods Matter https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380985/ Has anyone explored this?

Two studies presented exciting advancements in the treatment of chronic lymphocytic leukemia (CLL): Jennifer Brown, MD, PhD, presented findings that a novel, fixed-duration drug combination — consisting of a second-generation BTK inhibitor, called acalabrutinib, plus a BCL-2 inhibitor (venetoclax

Below are the notes: There is mild leukocytosis with lymphocytosis The lymphocytes comprise of predominantly small mature forms and a subpopulation with clumped chromatin highly suspicious for chronic lymphocytic leukemia. I know this isn't a dr site but is it time to visit him again?

[i] Abstract[/i] [i][/i] [i]The proliferation and survival of chronic lymphocytic leukemia (CLL) cells are heavily dependent on B-cell receptor (BCR) signaling and resistance to apoptosis.

Leukemia: Clinical and Epidemiological [i]Fixed-Duration Acalabrutinib Plus Venetoclax with or without Obinutuzumab Versus Chemoimmunotherapy for First-Line Treatment of Chronic Leukemia: Interim Analysis of the Multicenter, Open-Label, Randomized, Phase 3 AMPLIFY Trial[/i] AMPLIFY

We've had a few other posts recently regarding the TME; [i] • [/i]Targeting the tumor microenvironment for treating double refractory chronic leukemia posted by newyork917 https://healthunlocked.com/cllsupport/posts/private/150923620/targeting-the-tumor-microenvironment-for-treating-double-refractory-chronic-lymphocytic-leukemia