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Leuprolide
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LEUPRORELIN ACETATE
Any information on results or side effects for this ADT
Any information on results or side effects for this ADT
Stevegr
in
Advanced Prostate Cancer
10 months ago
I wonder if anyone knows why or has experienced a rise on PSA level (from 70 to 274), 6 months after radiation therapy (VMAT x 26 sessions)?
Before and after radiation therapy, dad was taking Bicalutamide 50 mg and Alfuzosin50 mg together with a quarterly Leuprorelin injection. This month (October), after receiving his Leuprorelin injection, Urologist advised to stop taking Bicalutamide as it is no longer effective due to hormone resistance
Before and after radiation therapy, dad was taking Bicalutamide 50 mg and Alfuzosin50 mg together with a quarterly Leuprorelin injection. This month (October), after receiving his Leuprorelin injection, Urologist advised to stop taking Bicalutamide as it is no longer effective due to hormone resistance
Iloveyoudad
in
Advanced Prostate Cancer
11 months ago
EMBARK trial results reported
[/i] https://www.pfizer.com/news/press-release/press-release-detail/phase-3-study-shows-xtandir-enzalutamide-plus-
leuprolide
[/i] https://www.pfizer.com/news/press-release/press-release-detail/phase-3-study-shows-xtandir-enzalutamide-plus-
leuprolide
GP24
in
Advanced Prostate Cancer
1 year ago
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Latest from PubMed
Impact of Concomitant Prostate Cancer Medications on Efficacy and Safety of Relugolix Versus
Leuprolide
in Men With Advanced Prostate Cancer. George DJ, Saad F, Cookson MS, Saltzstein DR, Tutrone R, Bossi A, Brown B, Selby B, Lu S, Buckley D, Tombal B, Shore ND.
Impact of Concomitant Prostate Cancer Medications on Efficacy and Safety of Relugolix Versus
Leuprolide
in Men With Advanced Prostate Cancer. George DJ, Saad F, Cookson MS, Saltzstein DR, Tutrone R, Bossi A, Brown B, Selby B, Lu S, Buckley D, Tombal B, Shore ND.
Magnus1964
in
Advanced Prostate Cancer
1 year ago
Just joined the club no one wants to be a member of in April 2023 - can Gleason 9 be cured ?
I am now on Eligard (
leuprolide
injection) and taking daily 240 mg of Erleada (apalutamide). I am treating at a NCI CCC and the third largest cancer hospital in the country. I am on a much more aggressive treatment plan than the one the local urologists suggested.
I am now on Eligard (
leuprolide
injection) and taking daily 240 mg of Erleada (apalutamide). I am treating at a NCI CCC and the third largest cancer hospital in the country. I am on a much more aggressive treatment plan than the one the local urologists suggested.
68Guitar
in
Advanced Prostate Cancer
11 months ago
Acute manic and psychotic symptoms following subcutaneousleuprolide in a male patient without prior psychiatric history:A case report
Upon the recommendation of his physician, the patient received
leuprolide
45 mg subcutaneously approximately 2 months prior to this admission; this dose is intended to be administered once every 6 months. His past medical history was otherwise unremarkable.
Upon the recommendation of his physician, the patient received
leuprolide
45 mg subcutaneously approximately 2 months prior to this admission; this dose is intended to be administered once every 6 months. His past medical history was otherwise unremarkable.
Carlosbach
in
Advanced Prostate Cancer
1 year ago
Agonists vs. antagonists (the latter not to be confused with a character in a novel!)
I started ADT exactly 8 years ago this month and during my off-and-on treatments since then have tried a half-dozen different drugs in the older agonist category (
leuprolide
, for example) attempting to find one with the fewest (or at least the most tolerable) side-effects.
I started ADT exactly 8 years ago this month and during my off-and-on treatments since then have tried a half-dozen different drugs in the older agonist category (
leuprolide
, for example) attempting to find one with the fewest (or at least the most tolerable) side-effects.
bluesnjazz
in
Advanced Prostate Cancer
7 months ago
The Use of Low Dose Estradiol to Ameliorate the Effects of ADT on Bone Mass Density
It should be noted that abiraterone + prednisone, as a second line therapy, was initiated in August 2020, ~58 months after ADT with
leuprolide
was started.
It should be noted that abiraterone + prednisone, as a second line therapy, was initiated in August 2020, ~58 months after ADT with
leuprolide
was started.
PhilipSZacarias
in
Advanced Prostate Cancer
1 year ago
Bill Bixby's Battle with Prostate Cancer
Bill Bixby, an actor known for his "Incredible Hulk" films and many other achievements, died of prostate cancer November 21,1993, having learned that he had the disease in April of 1991. He died at age 59. Here's his biography: https://www.closerweekly.com/posts/bill-bixby-hulk-star-remembered-by-his-official-biographer
Bill Bixby, an actor known for his "Incredible Hulk" films and many other achievements, died of prostate cancer November 21,1993, having learned that he had the disease in April of 1991. He died at age 59. Here's his biography: https://www.closerweekly.com/posts/bill-bixby-hulk-star-remembered-by-his-official-biographer
NecessarilySo
in
Advanced Prostate Cancer
1 year ago
Xtandi failure?
After a successful - but short - period on Bicalutamide + Leuprorelin my PSA has risen from 1.1 to 1.7, to (now) 3.3. My last scan showed some micro-mets on my back, but organs were clear.Is it safe to say that Xtandi does not work for me? To be honest, I've had a miserable time on it, culminating in
After a successful - but short - period on Bicalutamide + Leuprorelin my PSA has risen from 1.1 to 1.7, to (now) 3.3. My last scan showed some micro-mets on my back, but organs were clear.Is it safe to say that Xtandi does not work for me? To be honest, I've had a miserable time on it, culminating in
CrocodileShoes
in
Advanced Prostate Cancer
1 year ago
Xtandi (enzalutamide) alone is superior to ADT alone at preventing metastases in "high-risk" recurrent men
https://www.pfizer.com/news/press-release/press-release-detail/phase-3-study-shows-xtandir-enzalutamide-plus-
leuprolide
https://www.pfizer.com/news/press-release/press-release-detail/phase-3-study-shows-xtandir-enzalutamide-plus-
leuprolide
Tall_Allen
in
Advanced Prostate Cancer
1 year ago
CVD & GnRH agonists/antagonists
New study below [1]. Men with PCa have a greater risk of death from cardiovascular [CV] events, and androgen deprivation therapy [ADT] further increases that risk. The study looked at ADT drugs that target gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland. The drugs were Degarelix
New study below [1]. Men with PCa have a greater risk of death from cardiovascular [CV] events, and androgen deprivation therapy [ADT] further increases that risk. The study looked at ADT drugs that target gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland. The drugs were Degarelix
pca2004
in
Fight Prostate Cancer
2 years ago
What first?: Provenge or Nubeqa?
In general, androgen deprivation therapy (ADT) with
leuprolide
or GNRH antagonists remains a first-line therapy for patients who are still sensitive to androgen. For these patients, the antiresorptive agents denosumab and zoledronic acid can be used to help manage skeletal-related events (SREs).
In general, androgen deprivation therapy (ADT) with
leuprolide
or GNRH antagonists remains a first-line therapy for patients who are still sensitive to androgen. For these patients, the antiresorptive agents denosumab and zoledronic acid can be used to help manage skeletal-related events (SREs).
GeorgeGlass
in
Advanced Prostate Cancer
2 years ago
What should We do now?
My father,aged 59 was recently diagnosed with mHSPC.Our MO started 1st
leuprolide
injection on 5th July and he started bicalutamide along with it.Then he asked to stop bicalutamide and visit him with a PSA test. When we 1st checked psa it was 1389.
My father,aged 59 was recently diagnosed with mHSPC.Our MO started 1st
leuprolide
injection on 5th July and he started bicalutamide along with it.Then he asked to stop bicalutamide and visit him with a PSA test. When we 1st checked psa it was 1389.
sarkarsaikat2
in
Advanced Prostate Cancer
2 years ago
More calcium chat
I am currently in my 16th month of
leuprolide
treatment. At the beginning of my treatment a bone density scan found that I was "mildly osteopenic" . My oncologist has suggested that I take 1200mg calcium/day supplement.
I am currently in my 16th month of
leuprolide
treatment. At the beginning of my treatment a bone density scan found that I was "mildly osteopenic" . My oncologist has suggested that I take 1200mg calcium/day supplement.
mike__c
in
Advanced Prostate Cancer
2 years ago
Testosterone “Flare” (Or Testosterone?) Timing to Optimize Salvage Radiation Therapy
Also, some trial protocols have used bicalutamide and similar to block testosterone effects from the androgen “flare” when an ADT drug such as
leuprolide
or goserelin are first started. Note that the LHRH antagonists degarelix and relugolix do not have the androgen flare.
Also, some trial protocols have used bicalutamide and similar to block testosterone effects from the androgen “flare” when an ADT drug such as
leuprolide
or goserelin are first started. Note that the LHRH antagonists degarelix and relugolix do not have the androgen flare.
MateoBeach
in
Advanced Prostate Cancer
2 years ago
Testosterone “Flare” (Or Testosterone?) Timing to Optimize Salvage Radiation Therapy
Also, some trial protocols have used bicalutamide and similar to block testosterone effects from the androgen “flare” when an ADT drug such as
leuprolide
or goserelin are first started. Note that the LHRH antagonists degarelix and relugolix do not have the androgen flare.
Also, some trial protocols have used bicalutamide and similar to block testosterone effects from the androgen “flare” when an ADT drug such as
leuprolide
or goserelin are first started. Note that the LHRH antagonists degarelix and relugolix do not have the androgen flare.
MateoBeach
in
Fight Prostate Cancer
2 years ago
Lu-177 in Austria - Report and underlining high importance of both FDG and PSMA PET/CTs
PSA roughly halved after each of the first two infusion, prior to 3rd was added
leuprolide
11.25 mg. Last PSA test was on 4th of June and it was 3.62 ng/mL and testosterone at 11.
PSA roughly halved after each of the first two infusion, prior to 3rd was added
leuprolide
11.25 mg. Last PSA test was on 4th of June and it was 3.62 ng/mL and testosterone at 11.
CurrentSEO
in
Advanced Prostate Cancer
2 years ago
Prostate size reduction by hormone treatment - how long should this take?
Hi, I am beginning hormone therapy, which should hopefully reduce the size of my prostate. I have been given 11.5mg of Leuprorelin and 2 weeks of bicalutamide to reduce the testosterone flair up. How long should this take to actually reduce the size of my prostate?
Hi, I am beginning hormone therapy, which should hopefully reduce the size of my prostate. I have been given 11.5mg of Leuprorelin and 2 weeks of bicalutamide to reduce the testosterone flair up. How long should this take to actually reduce the size of my prostate?
swellonion230
in
Men's Health Forum
2 years ago
LUPRON vs FIRMAGON: Is The Debate About Superiority Over? With the December FDA approval of Relugolix the debate may now be moot
* FSH suppression was greater with relugolix than with
leuprolide
at all available time points. * Major cardiovascular events were seen in 2.9%, relugolix, compared to 6.2%, Lupron, representing a 54% reduction of cardiovascular event risk.
* FSH suppression was greater with relugolix than with
leuprolide
at all available time points. * Major cardiovascular events were seen in 2.9%, relugolix, compared to 6.2%, Lupron, representing a 54% reduction of cardiovascular event risk.
Scout4answers
in
Advanced Prostate Cancer
2 years ago
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