Is it time for interferon in low-risk patients with polycythaemia vera?

[Manouche]

« The use of interferon for the treatment of myeloproliferative neoplasms has a long tradition. Pioneering studies were done by Silver and Gisslinger in the late 1980s. 1 , 2 They showed interferon alfa (then conventional interferon alfa) to be effective in controlling erythrocytosis, thrombocytosis, pruritus, and other constitutional symptoms in patients with myeloproliferative neoplasms. From that time on, many studies, which included a small number of patients (about 400 patients in all studies together) and used more frequently pegylated interferon, confirmed the efficacy »

thelancet.com/journals/lanh...

[hunter5582]

I am hoping we will have access to Besremi in the USA before too long. It currently has Orphan Drug status. Hopefully the approval process will not get bogged down.