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Genetic background strongly influences the impact of carrying the Thr92Ala-DIO2 polymorphism in the male mouse
Are you male? Are you a mouse? Do you carry the Thr92Ala-DIO2 allele? Can you wait for the publication of this paper? Can you wait for the human version of this trial? And do you consider it necessary to wait for the eventual publication of the human trial before considering T3? It is undoubtedly
Are you male? Are you a mouse? Do you carry the Thr92Ala-DIO2 allele? Can you wait for the publication of this paper? Can you wait for the human version of this trial? And do you consider it necessary to wait for the eventual publication of the human trial before considering T3? It is undoubtedly
helvella
Thyroid UK
in
Thyroid UK
1 month ago
If you take a small dose of T3 (6mcg) does this slowly build up in your system or will it get used quickly every day?
I’m taking 6.25mcg of T3 for a week now I just wondered if this will build up in your system similar to T4? I know T4 is the storage hormone so that builds up slowly. I didn’t know whether the 6mcg will build up aswell as I was thinking of adding a little more but I don’t want to add more if it’s still
I’m taking 6.25mcg of T3 for a week now I just wondered if this will build up in your system similar to T4? I know T4 is the storage hormone so that builds up slowly. I didn’t know whether the 6mcg will build up aswell as I was thinking of adding a little more but I don’t want to add more if it’s still
ockerdoc
in
Thyroid UK
1 month ago
half life T3 in NDT
I've read over a period of time that T3 has half-life of anywhere from 2-2.5 days. I have, always, assumed (bad thing!) that was for synthetic T3. Anyone know, if that time-frame is applicable to dessicated T3? My FT3 shot up from 2.7 in late Feb. to 3.85 2 weeks ago. I had increased dose from97.5
I've read over a period of time that T3 has half-life of anywhere from 2-2.5 days. I have, always, assumed (bad thing!) that was for synthetic T3. Anyone know, if that time-frame is applicable to dessicated T3? My FT3 shot up from 2.7 in late Feb. to 3.85 2 weeks ago. I had increased dose from97.5
terebol
in
Thyroid UK
1 month ago
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Sudden crash back into fatigue.
After seeing my Endo last week, my T3 was kept the same (5mcg twice a day) and my t4 was put back up to 75. Usually it takes weeks before any difference shows doesn’t it? It wouldn’t be any difference in this case? The day after I started back on the higher dose I felt exhausted, insomnia and poor sleep
After seeing my Endo last week, my T3 was kept the same (5mcg twice a day) and my t4 was put back up to 75. Usually it takes weeks before any difference shows doesn’t it? It wouldn’t be any difference in this case? The day after I started back on the higher dose I felt exhausted, insomnia and poor sleep
Loopnova
in
Thyroid UK
1 month ago
reverse t3 testing.
I’m on a journey with t3 so far taking has not affected serum t3 levels and I have read that reverse t3 can block active t3. Has anyone here tested for this and did you find it useful? I understand it is a somewhat controversial test in the medical world Thanks!
I’m on a journey with t3 so far taking has not affected serum t3 levels and I have read that reverse t3 can block active t3. Has anyone here tested for this and did you find it useful? I understand it is a somewhat controversial test in the medical world Thanks!
Mag999
in
Thyroid UK
1 month ago
help needing t4
I wonder if anyone could help me I need to buy a top up of t4 without a prescription if someone could be as helpful as to give me an email address thankyou
I wonder if anyone could help me I need to buy a top up of t4 without a prescription if someone could be as helpful as to give me an email address thankyou
Kowbie
in
Thyroid UK
1 month ago
just wanted to see if everything is normal….
good morning, or afternoon…. I’ve only been dealing with hypothyroidism a short time, most just feeling exhausted, at the beginning had many other symptoms and of course weight is an issue. I am attaching two screenshots. One is my last TSH results, as those are the only tests my GP would do. Yesterday
good morning, or afternoon…. I’ve only been dealing with hypothyroidism a short time, most just feeling exhausted, at the beginning had many other symptoms and of course weight is an issue. I am attaching two screenshots. One is my last TSH results, as those are the only tests my GP would do. Yesterday
Tiff567
in
Thyroid UK
7 months ago
Hypo book recommendations please UK
Hi, please can someone recommend a book to start to understand likely hypothyroidism? A UK publication please. I joined yesterday and am just trying to get my head around it all. I have lots of symptoms and my TSH is creeping up with TS4 and especially TS3 scratching the bottom of the normal range
Hi, please can someone recommend a book to start to understand likely hypothyroidism? A UK publication please. I joined yesterday and am just trying to get my head around it all. I have lots of symptoms and my TSH is creeping up with TS4 and especially TS3 scratching the bottom of the normal range
Fizzwhizz
in
Thyroid UK
7 months ago
TSH dropping, but FT4 stuck
I started levothyroxine on 10th August on 25mcg, then went up to 50mcg in September, then 75mcg Nov and I'm now alternating 75/100mcg every day. My TSH has dropped considerably, however my FT4 has got stuck at the very bottom end of normal and doesn't seem to be rising despite me increasing the dose
I started levothyroxine on 10th August on 25mcg, then went up to 50mcg in September, then 75mcg Nov and I'm now alternating 75/100mcg every day. My TSH has dropped considerably, however my FT4 has got stuck at the very bottom end of normal and doesn't seem to be rising despite me increasing the dose
TheSnufkin
in
Thyroid UK
4 months ago
Hypo after all?
Hello everyone, this is my first post, though I’ve been gleaning pearls of wisdom from this site for a couple of years, so thank you all! I’m a 60-year-old male. I’ve had chronic fatigue since 1988; tight forehead pain and a horrible “saturated brain” feeling since the late 1990s (brought on by reading
Hello everyone, this is my first post, though I’ve been gleaning pearls of wisdom from this site for a couple of years, so thank you all! I’m a 60-year-old male. I’ve had chronic fatigue since 1988; tight forehead pain and a horrible “saturated brain” feeling since the late 1990s (brought on by reading
KingJohnVII
in
Thyroid UK
4 months ago
Hypothyroid - Vit & iron levels
Hello, As recommended by this brilliant group, I have had my vitamin and iron levels tested through medichecks. My results have come back all in range, thankfully, but I know that sometimes ‘normal’ or ‘in range’ isn’t optimum. Would someone be able to look at these please and let me know any thoughts
Hello, As recommended by this brilliant group, I have had my vitamin and iron levels tested through medichecks. My results have come back all in range, thankfully, but I know that sometimes ‘normal’ or ‘in range’ isn’t optimum. Would someone be able to look at these please and let me know any thoughts
Lola33
in
Thyroid UK
2 months ago
Are these results "subclinical"?
My latest two blood tests are below. First blood test: TSH: 4.16 (range 0.27 - 4.2) T4: 11.4 (range 11.9 - 21.6) BELOW Second blood test: TSH: 4.49 (range 0.35 - 4.94) T4: 12.7 (range 9.0 - 19.1) T3: 4.6 (range 2.4 - 6.0) Because my TSH is not above 5 (although 0.04 away
My latest two blood tests are below. First blood test: TSH: 4.16 (range 0.27 - 4.2) T4: 11.4 (range 11.9 - 21.6) BELOW Second blood test: TSH: 4.49 (range 0.35 - 4.94) T4: 12.7 (range 9.0 - 19.1) T3: 4.6 (range 2.4 - 6.0) Because my TSH is not above 5 (although 0.04 away
Granolalovers2
in
Thyroid UK
2 months ago
tsh 0?
Hi wondering if anyone can decifer my results until my gp gets back to me in a few days. I’ve been off levothyroxine for 10 years now (I was on it previously for 5 years as my tsh was 6.8 but stopped as my levels returned to normal). I only had it tested as I’m trying to get pregnant and wondered if
Hi wondering if anyone can decifer my results until my gp gets back to me in a few days. I’ve been off levothyroxine for 10 years now (I was on it previously for 5 years as my tsh was 6.8 but stopped as my levels returned to normal). I only had it tested as I’m trying to get pregnant and wondered if
Victoria27
in
Thyroid UK
4 months ago
low resting heart rate
Hi All, I have Low resting heart rate, regardless of upping dose. I’ve upped my T3 meds from 20mcg to 25mcg and I take 100mcg of Levo and my resting hr stays at 52/51bpm my resting heart rate was the same at 15mcg T3 too. Initially when I up the dose for 2-3 days resting heart rate will increase to
Hi All, I have Low resting heart rate, regardless of upping dose. I’ve upped my T3 meds from 20mcg to 25mcg and I take 100mcg of Levo and my resting hr stays at 52/51bpm my resting heart rate was the same at 15mcg T3 too. Initially when I up the dose for 2-3 days resting heart rate will increase to
Thyroid_mum
in
Thyroid UK
1 month ago
Advice on recent bloods please.
Good afternoon everyone, just looking some advice from the fonts of knowledge on here regarding latest MMH bloods.Started T4/T3 combo ten weeks ago(125mcg T4 + 6.25mcg T3 daily)Felt as well as I had in two years but in last couple of days I've had some symptoms creep in namely shoulder weakness, feeling
Good afternoon everyone, just looking some advice from the fonts of knowledge on here regarding latest MMH bloods.Started T4/T3 combo ten weeks ago(125mcg T4 + 6.25mcg T3 daily)Felt as well as I had in two years but in last couple of days I've had some symptoms creep in namely shoulder weakness, feeling
SovietSong
in
Thyroid UK
4 months ago
HRT, low white blood cell count & NDT
I have been having appointments with my GP to try and get an HRT prescription. She wanted a blood test doing first - I have been taking NDT for about 8 years (doing really well on it) and basically my GP didn't understand it, stopped calling me in for blood tests and I haven't been for years. The blood
I have been having appointments with my GP to try and get an HRT prescription. She wanted a blood test doing first - I have been taking NDT for about 8 years (doing really well on it) and basically my GP didn't understand it, stopped calling me in for blood tests and I haven't been for years. The blood
Raucous
in
Thyroid UK
2 months ago
Can anyone comment on my daughter's blood tests and advise what - if anything - we should do next?
My daughter is 18. I first requested blood tests with the GP when she was 15. This was during covid. I had to fight over the phone for them but she'd put on weight rapidly, she especially looked to be retaining fluid in her legs, feet, hands and face. Other symptoms = tiredness, slow movements, dry eyes
My daughter is 18. I first requested blood tests with the GP when she was 15. This was during covid. I had to fight over the phone for them but she'd put on weight rapidly, she especially looked to be retaining fluid in her legs, feet, hands and face. Other symptoms = tiredness, slow movements, dry eyes
ReaCoe
in
Thyroid UK
1 month ago
Why does Levothyroxine cause weight gain if it treats hypothyroidism, weight gain being a hypo symptom?
Shouldn't it help rectify hypo symptoms not make them worse? This baffles me! I wish I could revert back to Levothyroxine and use it together with T3 as NDT is extortionately priced, and not working brilliantly for me anymore, however, weight gain is my biggest fear, and I read so much about this on
Shouldn't it help rectify hypo symptoms not make them worse? This baffles me! I wish I could revert back to Levothyroxine and use it together with T3 as NDT is extortionately priced, and not working brilliantly for me anymore, however, weight gain is my biggest fear, and I read so much about this on
MindfulMoments
in
Thyroid UK
1 month ago
Thyroid uptake scan results
hi folks, In February I was diagnosed as hyperthyroid. My T4 was high at 38 (ref range 11-22). TPOAb high at 178 (range 0-35). TRAb negative at 3 (ref 0-3.3). I was referred recently for a thyroid uptake scan to conclude Graves diagnosis. Findings: The thyroid gland is not enlarged however there
hi folks, In February I was diagnosed as hyperthyroid. My T4 was high at 38 (ref range 11-22). TPOAb high at 178 (range 0-35). TRAb negative at 3 (ref 0-3.3). I was referred recently for a thyroid uptake scan to conclude Graves diagnosis. Findings: The thyroid gland is not enlarged however there
Hungryallthetimes
in
Thyroid UK
1 month ago
T3 in Crete
Hi, I am going to Crete and would like to pick up some T3, has anyone been recently and is easy to buy? Thanks very much.
Hi, I am going to Crete and would like to pick up some T3, has anyone been recently and is easy to buy? Thanks very much.
Bollieforme
in
Thyroid UK
1 month ago
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