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Experiences with
Fludarabine, cyclophosphamide and rituximab (FCR)
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V+O or FCR
He can choose between
fcr
and v + o, which has only recently been approved as an initial therapy in Germany. we clearly tend towards the latter, but I would still like to ask if
fcr
should be considered?
He can choose between
fcr
and v + o, which has only recently been approved as an initial therapy in Germany. we clearly tend towards the latter, but I would still like to ask if
fcr
should be considered?
Germanguest
in
CLL Support
4 years ago
Pneumococcal vaccine
I had the pneumococcal vaccine two or three years ago, then had
FCR
chemotherapy which finished in October 2018. I’ve been invited for a second pneumococcal jab next week. My haematologist is aware. I thought I’d check to see if anyone else has done the same, and if there’s any reason I shouldn’t.
I had the pneumococcal vaccine two or three years ago, then had
FCR
chemotherapy which finished in October 2018. I’ve been invited for a second pneumococcal jab next week. My haematologist is aware. I thought I’d check to see if anyone else has done the same, and if there’s any reason I shouldn’t.
Graham2222
in
CLL Support
4 years ago
fatigue
So here I am 2yrs and 4 mths post
FCR
(6 cycles) and several months of bone marrow not producing red cells (recovered from that 8mths ago) and I'm still struggling with erratic and intermittent debilitating fatigue. I understand this affects different cancer groups.
So here I am 2yrs and 4 mths post
FCR
(6 cycles) and several months of bone marrow not producing red cells (recovered from that 8mths ago) and I'm still struggling with erratic and intermittent debilitating fatigue. I understand this affects different cancer groups.
Jotame
in
CLL Support
4 years ago
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Time-to-progression after front-line FCR for CLL: a retrospective, multicohort study
It has been known for some time that
FCR
can produce very long remissions (perhaps cures) for some patients with mutated CLL.
It has been known for some time that
FCR
can produce very long remissions (perhaps cures) for some patients with mutated CLL.
Jm954
Administrator
in
CLL Support
4 years ago
Myelodyplastic Syndrome (MDS)
In my previous post I wrote about reaching a point 18months after completing
FCR
where my bone marrow stopped producing red cells. This got a diagnosis of MDS which was expected to be irreversible.
In my previous post I wrote about reaching a point 18months after completing
FCR
where my bone marrow stopped producing red cells. This got a diagnosis of MDS which was expected to be irreversible.
Jotame
in
CLL Support
4 years ago
Younger, Fit Patients With CLL: Goal Remains Undetectable Minimal Residual Disease and Time-Limited Therapy
Adverse events of grade 3 or higher were similar between the ibrutinib/rituximab and
FCR
arms, with more nonhematologic toxicity with ibrutinib/rituximab and more hematologic toxicity with
FCR
.
Adverse events of grade 3 or higher were similar between the ibrutinib/rituximab and
FCR
arms, with more nonhematologic toxicity with ibrutinib/rituximab and more hematologic toxicity with
FCR
.
Jm954
Administrator
in
CLL Support
4 years ago
Ibrutinib plus fludarabine, cyclophosphamide, and rituximab as initial treatment for younger patients with CLL
The trial was based on the premise that time-limited ibrutinib plus
FCR
would induce durable responses in younger fit patients with chronic lymphocytic leukaemia.
The trial was based on the premise that time-limited ibrutinib plus
FCR
would induce durable responses in younger fit patients with chronic lymphocytic leukaemia.
Jm954
Administrator
in
CLL Support
4 years ago
In remission after FCR treatment for CLL 7yrs ago. Should I be shielding because of Covid? I did not have a letter from my GP. I am 63yrs.
Now in a household with 2 frontline health workers.
Now in a household with 2 frontline health workers.
Jessian2
in
CLL Support
4 years ago
Duvelisib + FCR (DFCR) frontline therapy for younger CLL patients - study results (Aug. 2020)
younger patients, the 3-year PFS was 89% for IR and 73% for
FCR
. https://www.nejm.org/doi/full/10.1056/nejmoa1817073
younger patients, the 3-year PFS was 89% for IR and 73% for
FCR
. https://www.nejm.org/doi/full/10.1056/nejmoa1817073
avzuclav
in
CLL Support
4 years ago
Does FCR cause hair loss?
Drear group Does
FCR
cause hairs doss? And is
FCR
pain full ? Thank you
Drear group Does
FCR
cause hairs doss? And is
FCR
pain full ? Thank you
Nour80Leen2011
in
CLL Support
4 years ago
Final treatment free day
I have one last day before starting
FCR
. The to do list includes a coastal bike ride, a conquer of a hill and the making of a large Sherry trifle plus a full English.* How did you spend that last ‘normal’ day? *Plans subject to change 😊😊(slight 😥 eek)
I have one last day before starting
FCR
. The to do list includes a coastal bike ride, a conquer of a hill and the making of a large Sherry trifle plus a full English.* How did you spend that last ‘normal’ day? *Plans subject to change 😊😊(slight 😥 eek)
HarryMet
in
CLL Support
4 years ago
Schematic for CLL treatment?
(am not talking the nhs system who seem to just offer you
fcr
to start with as a default regardless as far as I can make out - more like a doc who had all options open). Thanks very much.
(am not talking the nhs system who seem to just offer you
fcr
to start with as a default regardless as far as I can make out - more like a doc who had all options open). Thanks very much.
Research123
in
CLL Support
4 years ago
day 1 fcr ,,but un-mutated
hi thankyou for all your replys,well it was day 1 today on
fcr
everything went smooth day 2 tommorow hope it goes the same ,today i asked the nurse what my mutation was she replayed and said im un-mutated now is it ok to be on
fcr
if you are unmutated just made me feel a bit worried i asked her before
hi thankyou for all your replys,well it was day 1 today on
fcr
everything went smooth day 2 tommorow hope it goes the same ,today i asked the nurse what my mutation was she replayed and said im un-mutated now is it ok to be on
fcr
if you are unmutated just made me feel a bit worried i asked her before
kel555
in
CLL Support
4 years ago
FCR oral versus iv
Is there anything else I should consider if needing tx with
FCR
? Thanks
Is there anything else I should consider if needing tx with
FCR
? Thanks
CarpeDiem03
in
CLL Support
4 years ago
FCR
I’ll avoid
FCR
at all. Dangerous and tricky. Increase the probability of AL occurrence as well as second neoplasm and Richter transformation in the long run. You have to be "fit patient” to receive
FCR
, IGHV mutated and without tp53 mutation or 17p deletion.
I’ll avoid
FCR
at all. Dangerous and tricky. Increase the probability of AL occurrence as well as second neoplasm and Richter transformation in the long run. You have to be "fit patient” to receive
FCR
, IGHV mutated and without tp53 mutation or 17p deletion.
Rccfrc00
in
CLL Support
4 years ago
FCR veterans
hi all iam due to start
fcr
on the 11 august on flair trial not realy happy due to the covid ,well my question is will it work i have been on w&w for 7yrs i have no tp53 and others and i dont know if iam mutated or un mutated could i be mutated if i have had cll for this long, realy need some answers
hi all iam due to start
fcr
on the 11 august on flair trial not realy happy due to the covid ,well my question is will it work i have been on w&w for 7yrs i have no tp53 and others and i dont know if iam mutated or un mutated could i be mutated if i have had cll for this long, realy need some answers
kel555
in
CLL Support
4 years ago
flair ..fcr
for a few more weeks to see how the covid pans out in my area ,,my bloods are heambolign 99 ...wbc 199 ...plts 116..lymphocytes 160 ... just getting a bit concerned about this
fcr
and infections ,thankyou ,,kel
for a few more weeks to see how the covid pans out in my area ,,my bloods are heambolign 99 ...wbc 199 ...plts 116..lymphocytes 160 ... just getting a bit concerned about this
fcr
and infections ,thankyou ,,kel
kel555
in
CLL Support
4 years ago
Show I aim to try to walk with this condition
Medics say it’s very rear and I take ibrutinib orally plus the R from
FCR
in IV form and the triple chemo dose in the lumber region. The prognosis I have is quite stark and it’s not more than a year! I’m aged 64 Today is the first day I feel okay but am still dizzy and walk slowly.
Medics say it’s very rear and I take ibrutinib orally plus the R from
FCR
in IV form and the triple chemo dose in the lumber region. The prognosis I have is quite stark and it’s not more than a year! I’m aged 64 Today is the first day I feel okay but am still dizzy and walk slowly.
Caoimh37
in
Couch to 5K
4 years ago
Can sinemet cr, go together with sinemet 25/250.
Sinemet
Sinemet
Masterka
in
Cure Parkinson's
4 years ago
Returning to work
I finished treatment for CLL in 2016 [
FCR
]. My health has been remarkably good considering [apart from sepsis after the first treatment]. I returned to work after treatment and I've been lucky [so far!] My last blood count in July '20 was satisfactory.
I finished treatment for CLL in 2016 [
FCR
]. My health has been remarkably good considering [apart from sepsis after the first treatment]. I returned to work after treatment and I've been lucky [so far!] My last blood count in July '20 was satisfactory.
Paintsh
in
CLL Support
4 years ago
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