Germline Testing for Men With Prostate Cancer
, with a subsequent study reporting improved cause-specific and progression-free survival among men with mCRPC and BRCA2 mutations treated with first-line abiraterone or enzalutamide over taxanes.9,10 Indeed, mutations in multiple genes (BRCA2, BRCA1, ATM, CHEK2, PALB2, RAD51D, NBN, MLH1, MSH2, PMS2,
, with a subsequent study reporting improved cause-specific and progression-free survival among men with mCRPC and BRCA2 mutations treated with first-line abiraterone or enzalutamide over taxanes.9,10 Indeed, mutations in multiple genes (BRCA2, BRCA1, ATM, CHEK2, PALB2, RAD51D, NBN, MLH1, MSH2, PMS2,