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Biotin and dopamine transport
Dopamine
transport dependent on biotin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157066/
Dopamine
transport dependent on biotin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157066/
Gigi216
in
Cure Parkinson's
1 year ago
Vitamin B2 Deficiency Can Cause B6 Toxicity! PWP Are Commonly Deficient In B2.
www.frontiersin.org/files/Articles/276491/fneur-08-00333-HTML/image_m/fneur-08-00333-g002.jpg From: https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2017.00333/full Vitamin B6 is a coenzyme required for over 100 different biochemical transformations, including conversion of levodopa to
dopamine
www.frontiersin.org/files/Articles/276491/fneur-08-00333-HTML/image_m/fneur-08-00333-g002.jpg From: https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2017.00333/full Vitamin B6 is a coenzyme required for over 100 different biochemical transformations, including conversion of levodopa to
dopamine
park_bear
in
Cure Parkinson's
7 months ago
Ozempic effects dopamine?
This article implies that Ozempic increases
dopamine
: https://www.msn.com/en-us/health/medical/some-people-taking-ozempic-say-it-helps-with-addiction-they-could-be-onto-something-according-to-research/ar-AA1bEpxV I'm wondering if anyone here with PD uses Ozempic and if they noticed any positive
This article implies that Ozempic increases
dopamine
: https://www.msn.com/en-us/health/medical/some-people-taking-ozempic-say-it-helps-with-addiction-they-could-be-onto-something-according-to-research/ar-AA1bEpxV I'm wondering if anyone here with PD uses Ozempic and if they noticed any positive
pvw2
in
Cure Parkinson's
1 year ago
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On the Holistic origin of Parkinson's
The process would detect the origin event that gave rise to the disorder in each patient and could be a key factor in reducing the intensity of fear and with it the unconscious recognition that the
dopamine
production system can now be restored because the possibility of living another traumatic event
The process would detect the origin event that gave rise to the disorder in each patient and could be a key factor in reducing the intensity of fear and with it the unconscious recognition that the
dopamine
production system can now be restored because the possibility of living another traumatic event
ManuCalma
in
Cure Parkinson's
9 months ago
Dr Andy how to Taper off Dopamine Agonists and telling people they should not be prescribed.
Good to show doctors that they should not prescribe
dopamine
agonists . Also the previous video with Professor Allen apologising for starting people on
dopamine
agonists before he know it would cause augmentation.
Good to show doctors that they should not prescribe
dopamine
agonists . Also the previous video with Professor Allen apologising for starting people on
dopamine
agonists before he know it would cause augmentation.
Shumbah
in
Restless Legs Syndrome
1 year ago
Bayer Investing in New Cell Therapy Facility
About bemdaneprocel and Parkinson’s Disease Bemdaneprocel (BRT-DA01) is an investigational cell therapy designed to replace the
dopamine
producing neurons that are lost in Parkinson’s disease.
About bemdaneprocel and Parkinson’s Disease Bemdaneprocel (BRT-DA01) is an investigational cell therapy designed to replace the
dopamine
producing neurons that are lost in Parkinson’s disease.
redhawk1
in
Cure Parkinson's
8 months ago
Phase III trial for Cerevance’s lead CNS therapy, CVN424, in patients with Parkinson’s disease.
CVN424 is a non-
dopamine
therapy that inhibits G protein-coupled receptor 6 (GPR6), which is an orphan receptor as it has no naturally produced agonist that activates the receptor. The GPR6 inhibition can potentially improve motor and non-motor manifestations of Parkinson’s.
CVN424 is a non-
dopamine
therapy that inhibits G protein-coupled receptor 6 (GPR6), which is an orphan receptor as it has no naturally produced agonist that activates the receptor. The GPR6 inhibition can potentially improve motor and non-motor manifestations of Parkinson’s.
Farooqji
in
Cure Parkinson's
2 months ago
Roprinerole Withdrawl
My
dopamine
receptors are probably destroyed and am not looking forward to the upcoming reductions of Roprinerole. Any other suggestions? Thank you so much.
My
dopamine
receptors are probably destroyed and am not looking forward to the upcoming reductions of Roprinerole. Any other suggestions? Thank you so much.
Washguy731
in
Restless Legs Syndrome
11 months ago
Will b12 injection interfere with chorea/movement disorder?
I know movement disorders are triggered from overactivity of
dopamine
and then I have read b12 injection has some sort of
dopamine
affect. So I'm wondering if the b12 injection could make me worse What do you think?
I know movement disorders are triggered from overactivity of
dopamine
and then I have read b12 injection has some sort of
dopamine
affect. So I'm wondering if the b12 injection could make me worse What do you think?
Charts
in
Hughes Syndrome APS Forum
1 year ago
Advice needed
I have been on
Dopamine
meds since 2010 and am presently on 2mg Neupro patch which I was switched to in 2016 by a Neurologist. The inevitable Augmentation is now so bad I need to come off it.
I have been on
Dopamine
meds since 2010 and am presently on 2mg Neupro patch which I was switched to in 2016 by a Neurologist. The inevitable Augmentation is now so bad I need to come off it.
Annieapple
in
Restless Legs Syndrome
1 year ago
Augmentation
In my years with PLMD, I have taken almost everything, but not
dopamine
agonists. Is it correct that if you start and have success at a low dose -- and never increase it -- that you could avoid augmentation?
In my years with PLMD, I have taken almost everything, but not
dopamine
agonists. Is it correct that if you start and have success at a low dose -- and never increase it -- that you could avoid augmentation?
wantokporo
in
Restless Legs Syndrome
1 year ago
A cross in the sand
It appears that a person with PD has no
dopamine
supply, but it can be stimulated with levadopa, which is a great help. But when there is an abrupt end to the meds, the body goes into stress and manifests dyskinesia which is worsening the original problem.
It appears that a person with PD has no
dopamine
supply, but it can be stimulated with levadopa, which is a great help. But when there is an abrupt end to the meds, the body goes into stress and manifests dyskinesia which is worsening the original problem.
Meg024
in
Cure Parkinson's
1 year ago
Pycnogenol® supplementation alleviates symptoms of Parkinson's disease with mild cognitive impairment
Pycnogenol may also influence the release of catecholamines (including
dopamine
and norepinephrine) and nitric oxide synthesis. [/i]Whenever
dopamine
is mentioned I am cautious for my HWP.
Pycnogenol may also influence the release of catecholamines (including
dopamine
and norepinephrine) and nitric oxide synthesis. [/i]Whenever
dopamine
is mentioned I am cautious for my HWP.
Sydney75
in
Cure Parkinson's
1 year ago
Dystonia: WTF?!
This dystonia now, if I’m really low on
dopamine
, attacks my stomach, feet, back muscles, neck - and as I witnessed during my ‘no drugs allowed’ period - my jaw. When this strikes I’m in a truly awful state and need to be rescued with the Madopar that I mentioned above.
This dystonia now, if I’m really low on
dopamine
, attacks my stomach, feet, back muscles, neck - and as I witnessed during my ‘no drugs allowed’ period - my jaw. When this strikes I’m in a truly awful state and need to be rescued with the Madopar that I mentioned above.
jeeves19
in
Cure Parkinson's
11 months ago
Why I pay no attention to studies of PD in mice.
Perhaps the current rodent models of PD would be more predictive of what will translate into human studies if the time course of
dopamine
neuron degeneration could be mimicked and behavioral tests were designed to assess the more subtle symptoms ... ” “… Perhaps one of the most relevant examples … with
Perhaps the current rodent models of PD would be more predictive of what will translate into human studies if the time course of
dopamine
neuron degeneration could be mimicked and behavioral tests were designed to assess the more subtle symptoms ... ” “… Perhaps one of the most relevant examples … with
MBAnderson
in
Cure Parkinson's
10 months ago
What are ‘off’ periods – and how can they impact people with Parkinson’s disease?
“The ‘off’ state can kick in when levodopa is eliminated from our body – and people begin to express motor symptoms that are related to the low amount of
dopamine
going to the brain.”
“The ‘off’ state can kick in when levodopa is eliminated from our body – and people begin to express motor symptoms that are related to the low amount of
dopamine
going to the brain.”
Farooqji
in
Cure Parkinson's
1 year ago
The environment makes the cells says Bruce Lipton. The importance of isolating the supposedly sick person...
established by a process of assigning transgenerational information (mechanics unknown to science) whose trauma is originally It spreads among members of future generations, causing intense fear in those who host it that translates into constant oxidative stress to the limit of breaking the production of
dopamine
established by a process of assigning transgenerational information (mechanics unknown to science) whose trauma is originally It spreads among members of future generations, causing intense fear in those who host it that translates into constant oxidative stress to the limit of breaking the production of
dopamine
ManuCalma
in
Cure Parkinson's
8 months ago
Could Psychedelics help in Parkinsons Disease treatment?
- Symptom management - Some research indicates psychedelics may protect
dopamine
neurons or stimulate growth of new ones. Reopening plasticity periods could enhance this through combined psychedelic and neurostimulation therapies.
- Symptom management - Some research indicates psychedelics may protect
dopamine
neurons or stimulate growth of new ones. Reopening plasticity periods could enhance this through combined psychedelic and neurostimulation therapies.
pdpatient
in
Cure Parkinson's
10 months ago
Trying out L-dopa supplement
I'm sure that's why Wellbutrin (which is a
dopamine
and norepinephrine agonist) is an antidepressant. Still, I don't think I'm getting enough to help me with the motivation that
dopamine
is supposed to help with.
I'm sure that's why Wellbutrin (which is a
dopamine
and norepinephrine agonist) is an antidepressant. Still, I don't think I'm getting enough to help me with the motivation that
dopamine
is supposed to help with.
STEM_Dad
in
CHADD's Adult ADHD Support
3 months ago
Phenylethylamine is NOT Palmitoylethanolamide! They are both called PEA. I take Palmitoylethanolamide
Another signifi cant observation is that administration of β-PEA to rodents reduces striatal
dopamine
content and induces movement disorders similar to those of parkinsonian rodents. However, no reports are available on the extent of dopaminergic neuronal cell death after administration of β-PEA.
Another signifi cant observation is that administration of β-PEA to rodents reduces striatal
dopamine
content and induces movement disorders similar to those of parkinsonian rodents. However, no reports are available on the extent of dopaminergic neuronal cell death after administration of β-PEA.
Bolt_Upright
in
Cure Parkinson's
10 months ago
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