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HRT Question
I’m feeling so much better in myself and my husband says I’m much more relaxed, but still have a long list of ADHD symptoms and issues with executive functioning, I wonder if any of you ladies experienced this and if HRT helped, given that oestrogen and
dopamine
are interlinked?
I’m feeling so much better in myself and my husband says I’m much more relaxed, but still have a long list of ADHD symptoms and issues with executive functioning, I wonder if any of you ladies experienced this and if HRT helped, given that oestrogen and
dopamine
are interlinked?
Amazon07
in
Thyroid UK
9 months ago
How to escape Augmentation?
Does it mean my
dopamine
receptors are too damage to recover? I hope someone can guide me because I now think that the normal medical professionals cannot?
Does it mean my
dopamine
receptors are too damage to recover? I hope someone can guide me because I now think that the normal medical professionals cannot?
davchar23
in
Restless Legs Syndrome
1 year ago
the best probiotics for Parkinson's
I would like to try Lactobacillus plantarum PS128, which was originally isolated from a fermented foodstuff, has been shown, in multiple experimental models, to possess the characteristics of a psychobiotic, being able to modulate
dopamine
and serotonin levels in the central nervous system, as well as
I would like to try Lactobacillus plantarum PS128, which was originally isolated from a fermented foodstuff, has been shown, in multiple experimental models, to possess the characteristics of a psychobiotic, being able to modulate
dopamine
and serotonin levels in the central nervous system, as well as
SereAve
in
Cure Parkinson's
4 days ago
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Autism and RLS
Having read about the
dopamine
link, wondering if this explains his cycles of being content and happy for a period of time then low mood and needing to hit his thighs -walks in the park support him enormously - I found this forum whilst investigating reasons for his behaviours.
Having read about the
dopamine
link, wondering if this explains his cycles of being content and happy for a period of time then low mood and needing to hit his thighs -walks in the park support him enormously - I found this forum whilst investigating reasons for his behaviours.
AddSchool
in
Restless Legs Syndrome
1 year ago
Augmentation - Can Aripiprazole reduce symptoms
https://www.tandfonline.com/doi/full/10.2147/NSS.S421189 An interesting article on alleviating the symptoms of
dopamine
agonist augmentation with Aripiprazole. Aripiprazole is an atypical anti psychotic and there are a few reports from 2010 that showed it might help RLS.
https://www.tandfonline.com/doi/full/10.2147/NSS.S421189 An interesting article on alleviating the symptoms of
dopamine
agonist augmentation with Aripiprazole. Aripiprazole is an atypical anti psychotic and there are a few reports from 2010 that showed it might help RLS.
Joolsg
in
Restless Legs Syndrome
1 year ago
Scientists Offer a New Explanation for Long Covid
Could a similar mechanism with a past virus lead to a deficiency in
dopamine
?
Could a similar mechanism with a past virus lead to a deficiency in
dopamine
?
LAJ12345
in
Cure Parkinson's
1 year ago
Newly Discovered Trigger of Parkinson’s Upends Common Beliefs
But the new study suggests that a dysfunction in the neuron’s synapses — the tiny gap across which a neuron can send an impulse to another neuron — leads to deficits in
dopamine
and precedes the neurodegeneration.
But the new study suggests that a dysfunction in the neuron’s synapses — the tiny gap across which a neuron can send an impulse to another neuron — leads to deficits in
dopamine
and precedes the neurodegeneration.
Farooqji
in
Cure Parkinson's
1 year ago
sulfur in dopamine agonists
I tried
dopamine
agonists: Pramipexole and Rotigotine. Both give me stomach problems. My neurologist says they are the lightest and that the others on the market have more side effects. It is true? I have seen the chemical formulas of these drugs: C19H25NOS and C10H17N3S both contain S (sulphur).
I tried
dopamine
agonists: Pramipexole and Rotigotine. Both give me stomach problems. My neurologist says they are the lightest and that the others on the market have more side effects. It is true? I have seen the chemical formulas of these drugs: C19H25NOS and C10H17N3S both contain S (sulphur).
michelagvolpe
in
Cure Parkinson's
1 year ago
High-dose DHA and dyskinesia (my experience so far)
Mischley's DHA protocol while watching one of her PD School videos (in the "
Dopamine
Repletion" section). I immediately purchased the Super DHA Forte Liquid and started taking 2 teaspoons per day on December 15, 2023. She recommends this high dose for a month or two.
Mischley's DHA protocol while watching one of her PD School videos (in the "
Dopamine
Repletion" section). I immediately purchased the Super DHA Forte Liquid and started taking 2 teaspoons per day on December 15, 2023. She recommends this high dose for a month or two.
1LittleWillow
in
Cure Parkinson's
9 months ago
How to use the prone position more efficiently
Moving into the prone position might change the pressure around the pituitary gland, potentially stimulating it to produce more hormones, which could then increase
dopamine
production.
Moving into the prone position might change the pressure around the pituitary gland, potentially stimulating it to produce more hormones, which could then increase
dopamine
production.
VladimirF
in
Restless Legs Syndrome
10 months ago
Dysfunctional Synapses
But the new study suggests that a dysfunction in the neuron’s synapses — the tiny gap across which a neuron can send an impulse to another neuron — leads to deficits in
dopamine
and precedes the neurodegeneration.
But the new study suggests that a dysfunction in the neuron’s synapses — the tiny gap across which a neuron can send an impulse to another neuron — leads to deficits in
dopamine
and precedes the neurodegeneration.
roller2
in
Cure Parkinson's
1 year ago
DO YOUR RESEARCH. Cure yourself.
Positive findings of the study demonstrated that ingestion of KSOP1009 was successful in the protection of MPTP toxicity, where this could be correlated with
dopamine
reduction that also decreases ROS and restores mitochondrial roles .
Positive findings of the study demonstrated that ingestion of KSOP1009 was successful in the protection of MPTP toxicity, where this could be correlated with
dopamine
reduction that also decreases ROS and restores mitochondrial roles .
pdefa
in
Cure Parkinson's
8 months ago
New therapies for RLS!! New research finally!
Stefan Clemens at Brody school of medicine...he discovered why augmentation happens...the dopaminergic drugs actually stimulate
dopamine
subtype D!. This is HUGE NEWS! They are about to start the second trials. He emailed me immediately which was amazing.
Stefan Clemens at Brody school of medicine...he discovered why augmentation happens...the dopaminergic drugs actually stimulate
dopamine
subtype D!. This is HUGE NEWS! They are about to start the second trials. He emailed me immediately which was amazing.
beartoothgirl406
in
Restless Legs Syndrome
10 months ago
Stem Cell Therapy for Parkinsons
https://www.ucihealth.org/blog/2024/01/restoring-
dopamine
-in-parkinsons-patients Very exiciting news! Hoping they have found a new effective treatment...
https://www.ucihealth.org/blog/2024/01/restoring-
dopamine
-in-parkinsons-patients Very exiciting news! Hoping they have found a new effective treatment...
staceysack
in
Cure Parkinson's
7 months ago
40 years of RLS
Over the past 15 years, it has been diagnosed as severe.I have tried all of the
dopamine
drugs, none worked except for pramipexol, I have augmented and spent the past year still trying to get off this. I am under a sleep specialist and on 50mg of oxycodone per day.
Over the past 15 years, it has been diagnosed as severe.I have tried all of the
dopamine
drugs, none worked except for pramipexol, I have augmented and spent the past year still trying to get off this. I am under a sleep specialist and on 50mg of oxycodone per day.
Trish8433
in
Restless Legs Syndrome
1 year ago
DAWS success story?
But the neurologist told me that sometimes, quitting
dopamine
agonist can be impossible as DAWS can become permanent. In this case, I will have to add rotigotine to the mix..
But the neurologist told me that sometimes, quitting
dopamine
agonist can be impossible as DAWS can become permanent. In this case, I will have to add rotigotine to the mix..
Mikatrap
in
Restless Legs Syndrome
11 months ago
1st transplant done in trial of Parkinson’s cell therapy ANPD001
This experimental therapy for Parkinson’s uses a type of stem cell called an induced pluripotent stem cell, or iPSC, which is able to generate nearly any type of cell in the body — including
dopamine
-producing neurons. Its manufacturing is a three-step process.
This experimental therapy for Parkinson’s uses a type of stem cell called an induced pluripotent stem cell, or iPSC, which is able to generate nearly any type of cell in the body — including
dopamine
-producing neurons. Its manufacturing is a three-step process.
Farooqji
in
Cure Parkinson's
5 months ago
park_bear made a very compelling argument for taking P5P (active B6)
If you are going to neutralize the carbidopa in your system, it makes sense not to while you maybe don’t need extra
dopamine
in your brain. And, because I am afraid to take before bed, I decided to try first thing in the morning.
If you are going to neutralize the carbidopa in your system, it makes sense not to while you maybe don’t need extra
dopamine
in your brain. And, because I am afraid to take before bed, I decided to try first thing in the morning.
Gcf51
in
Cure Parkinson's
9 months ago
Acetyl DL Leucine
Acetyl-DL-leucine in two individuals with REM sleep behavior disorder improves symptoms, reverses loss of striatal
dopamine
-transporter binding and stabilizes pathological metabolic brain pattern—case reports: https://www.nature.com/articles/s41467-024-51502-7#:~:text=In%202020%2C%20we%20treated%20a
Acetyl-DL-leucine in two individuals with REM sleep behavior disorder improves symptoms, reverses loss of striatal
dopamine
-transporter binding and stabilizes pathological metabolic brain pattern—case reports: https://www.nature.com/articles/s41467-024-51502-7#:~:text=In%202020%2C%20we%20treated%20a
MrCrow
in
Restless Legs Syndrome
24 days ago
Drug fails in Phase II trial for treating Parkinson's Disease - Exenatide (Byetta, Bydureon)
Secondary endpoints included MDS-UPDRS part I scores (non-motor aspects of experiences of daily living), clinical and patient impressions of severity, cognitive test scores, and
dopamine
transporter imaging parameters. No secondary endpoint differed from placebo at either dose.
Secondary endpoints included MDS-UPDRS part I scores (non-motor aspects of experiences of daily living), clinical and patient impressions of severity, cognitive test scores, and
dopamine
transporter imaging parameters. No secondary endpoint differed from placebo at either dose.
Baron1
in
Cure Parkinson's
9 months ago
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