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Expanded label sought for 177Lu-PSMA-617 in prostate cancer: about time
I have already done the taxane part and I would like to see how 177Lu performs as first line...but this is also interesting, it seems more effective than a change in ARPI in castration resistant setting "Data also showed that a PSA decline of at least 50% was more than 2.5 times more frequent with 177Lu-PSMA
I have already done the taxane part and I would like to see how 177Lu performs as first line...but this is also interesting, it seems more effective than a change in ARPI in castration resistant setting "Data also showed that a PSA decline of at least 50% was more than 2.5 times more frequent with 177Lu-PSMA
Maxone73
in
Advanced Prostate Cancer
5 months ago
Lynparza - warning!
I'm writing this in pure agony in hopes, that it might help someone in the future. My father is castrate resistant and when Xtandi stopped working, his MO put him on dexamethasone + abiraterone + Lynparza (olaparib). This combo is now registered in European Union even for men without BRCA mutation
I'm writing this in pure agony in hopes, that it might help someone in the future. My father is castrate resistant and when Xtandi stopped working, his MO put him on dexamethasone + abiraterone + Lynparza (olaparib). This combo is now registered in European Union even for men without BRCA mutation
MyDad76
in
Advanced Prostate Cancer
5 months ago
Update May 15, 2024
Hoping all is well with others on this site. UPDATE May 15 2024 I am concerned about results of the Right frontal skull SUV 5.3 previously 0.75. I have researched and really can't find any information that I can understand. Any replies would be greatly appreciated My husband had his PSMA PET/
Hoping all is well with others on this site. UPDATE May 15 2024 I am concerned about results of the Right frontal skull SUV 5.3 previously 0.75. I have researched and really can't find any information that I can understand. Any replies would be greatly appreciated My husband had his PSMA PET/
MsHope
in
Advanced Prostate Cancer
5 months ago
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Pluvicto damaging salivary glands?
Finished 6 rounds of Pluvicto 9-1-23. Now on ADT holiday since 1-1-24, psa unmeasurable so far. During the treatment, had increasingly serious drymouth and nasal congestion and irritation with bleeding, which I attributed to radiation damage. Since then, there has been some, slow improvement, but still
Finished 6 rounds of Pluvicto 9-1-23. Now on ADT holiday since 1-1-24, psa unmeasurable so far. During the treatment, had increasingly serious drymouth and nasal congestion and irritation with bleeding, which I attributed to radiation damage. Since then, there has been some, slow improvement, but still
Kayakbob
in
Advanced Prostate Cancer
5 months ago
High Gleason score + .2 PSA
Want to share this link about when to start salvage radiation after surgery. Only a few years ago, the cutoff PSA for starting radiation was .5 Now, my doc and others want to start before it gets to .2 (I'm at .11, and I have a "risk factor" due to Gleason 9 score) https://www.cancernetwork.com/view
Want to share this link about when to start salvage radiation after surgery. Only a few years ago, the cutoff PSA for starting radiation was .5 Now, my doc and others want to start before it gets to .2 (I'm at .11, and I have a "risk factor" due to Gleason 9 score) https://www.cancernetwork.com/view
SarcoPenyaJr
in
Prostate Cancer And Gay Men
5 months ago
Reference Library of Papers about Dutasteride for Treating Prostate Cancer
Here is a library of 20 papers about using Dutasteride to treat prostate cancer. In one study, Dutasteride monotherapy reduces PSA by 50%, reduces prostate volume by 25%, and reduces tumor volume by 30%, after 6 months of treatment, compared to placebo (Moore, 2017). https://pubmed.ncbi.nlm.nih.gov
Here is a library of 20 papers about using Dutasteride to treat prostate cancer. In one study, Dutasteride monotherapy reduces PSA by 50%, reduces prostate volume by 25%, and reduces tumor volume by 30%, after 6 months of treatment, compared to placebo (Moore, 2017). https://pubmed.ncbi.nlm.nih.gov
janebob99
in
Advanced Prostate Cancer
5 months ago
2018 still kicking
Good morning, Brothers. I was diagnosed on February 27th, 2018, and just got my most recent report. PSA is still 0.1 bone mets, which are still multiple but stable, either no uptake or diminished some. My only treatments have been Zytiga and Prendisone with Eligard injection every six months. I also
Good morning, Brothers. I was diagnosed on February 27th, 2018, and just got my most recent report. PSA is still 0.1 bone mets, which are still multiple but stable, either no uptake or diminished some. My only treatments have been Zytiga and Prendisone with Eligard injection every six months. I also
leo2634
in
Advanced Prostate Cancer
5 months ago
Rectitis caring
Diagnosed in may 2019...T3M1N0...GL 8 started ADT and had RT20 session nov 2019 Stopped ADT in march 2023....PSA < 0.02 since july 2020 In end 2020 started having stool blood ..occasionally then more frequent Consulted Gastro ...nothing to do and it will get worse he says with a smile Suggested
Diagnosed in may 2019...T3M1N0...GL 8 started ADT and had RT20 session nov 2019 Stopped ADT in march 2023....PSA < 0.02 since july 2020 In end 2020 started having stool blood ..occasionally then more frequent Consulted Gastro ...nothing to do and it will get worse he says with a smile Suggested
Karmaji
in
Advanced Prostate Cancer
5 months ago
Wife of Newly Diagnosed Husband - PSMA questions
Hi Everyone, We found out two weeks ago that my husband has high grade prostate cancer. He is 59. PSA 5.9. Gleason 4+5, 4+3 and 3+4. There was perineural invasion in one sample and intraductal in another. He has had an MRI and a CT scan, as well. He is scheduled for a bone scan next week. No prostate
Hi Everyone, We found out two weeks ago that my husband has high grade prostate cancer. He is 59. PSA 5.9. Gleason 4+5, 4+3 and 3+4. There was perineural invasion in one sample and intraductal in another. He has had an MRI and a CT scan, as well. He is scheduled for a bone scan next week. No prostate
EvFC
in
Advanced Prostate Cancer
6 months ago
Metastatic PC that produces no or low PSA
Hi All, Looking to connect with people with metastatic PC that produces no or low PSA I am 44 and was diagnosed with PC with a bone metastasis grade 4+5. My PSA at time of diagnosis was 0.54. I’m undergoing PEACE 1 protocol treatment. Finish RT and Doxetaxel still on Zytiga. I would love to connect
Hi All, Looking to connect with people with metastatic PC that produces no or low PSA I am 44 and was diagnosed with PC with a bone metastasis grade 4+5. My PSA at time of diagnosis was 0.54. I’m undergoing PEACE 1 protocol treatment. Finish RT and Doxetaxel still on Zytiga. I would love to connect
Jumpingbellybeans
in
Advanced Prostate Cancer
6 months ago
Asking for my dad!!
Hi all - I am new here. My dad was diagnosed with stage 4 prostate cancer with mets in his bones and lymph nodes in February 2024. He was diagnosed with adenocarcinoma with Gleason 8. He was started on hormone therapy and had bilateral orchiectomy as well. He is in great health apart - mentally and
Hi all - I am new here. My dad was diagnosed with stage 4 prostate cancer with mets in his bones and lymph nodes in February 2024. He was diagnosed with adenocarcinoma with Gleason 8. He was started on hormone therapy and had bilateral orchiectomy as well. He is in great health apart - mentally and
Justgettingitright
in
Advanced Prostate Cancer
6 months ago
PSMA PET Results - don’t know what to do next (more tests?)
Hi everyone, For those who have been following my dad was diagnosed with PCa on Jan 18th, PI-RADS 5, Gleason 8, PSA 10.4. He started 50mg of Casodex on March 8, and had Eligard 30mg injection March 26th. He has had bone scan (nothing notable), CT (nothing notable), MRI showed one of his pelvic
Hi everyone, For those who have been following my dad was diagnosed with PCa on Jan 18th, PI-RADS 5, Gleason 8, PSA 10.4. He started 50mg of Casodex on March 8, and had Eligard 30mg injection March 26th. He has had bone scan (nothing notable), CT (nothing notable), MRI showed one of his pelvic
Cafu6
in
Advanced Prostate Cancer
6 months ago
PSA following Lupron and question on scans
hi all, I am so happy to report that my dad has really improved following terrible side effects with his radiation treatment. I have posted before -he was having awful GI side effects which seemed to get worse following radiation completion. But this is all subsided which we are grateful for. dad
hi all, I am so happy to report that my dad has really improved following terrible side effects with his radiation treatment. I have posted before -he was having awful GI side effects which seemed to get worse following radiation completion. But this is all subsided which we are grateful for. dad
alysona828
in
Advanced Prostate Cancer
6 months ago
FG-3246 shows promising results in phase 1 trial
As mono therapy "data from the study showed that 36% of evaluable patients experienced at least a 50% reduction in prostate-specific antigen (PSA) levels from baseline. Among RECIST-evaluable patients, 20% demonstrated a partial response or a reduction in tumor size of at least 30%. The median duration
As mono therapy "data from the study showed that 36% of evaluable patients experienced at least a 50% reduction in prostate-specific antigen (PSA) levels from baseline. Among RECIST-evaluable patients, 20% demonstrated a partial response or a reduction in tumor size of at least 30%. The median duration
Maxone73
in
Advanced Prostate Cancer
6 months ago
FDA approves a new IND application of 225Ac-J591 (Actinium)
The FDA has granted clearance to an investigational new drug (IND) application for 225Ac-J591 (CONV01-α), a prostate-specific membrane antigen-targeted monoclonal antibody under investigation for the treatment of patients with advanced prostate cancer, announced Convergent Therapeutics, the developer
The FDA has granted clearance to an investigational new drug (IND) application for 225Ac-J591 (CONV01-α), a prostate-specific membrane antigen-targeted monoclonal antibody under investigation for the treatment of patients with advanced prostate cancer, announced Convergent Therapeutics, the developer
Maxone73
in
Advanced Prostate Cancer
6 months ago
Symptoms of PsA
Hello I wondered if anyone could share with me the symptoms of PsA? Although I have been told that I've probably had this for a while, the only sign, for years, was two slightly swollen toes which at times were a little sore. Well that's what I thought, until I started to realise that some foot pain
Hello I wondered if anyone could share with me the symptoms of PsA? Although I have been told that I've probably had this for a while, the only sign, for years, was two slightly swollen toes which at times were a little sore. Well that's what I thought, until I started to realise that some foot pain
looby24
in
Beyond Psoriasis
6 months ago
EBRT - Is it the right thing and what to expect?
After DX in November 2018 with Stage IV and Gleason of 5+4 and 4+5, and 5 years of ADT of Lupron (then Orgovyx), prednisone 5mg, and Zytiga 250mg with low fat breakfast, my PSA stayed stable at 0.4 or 0.5. At end of 2013, PSA started rising to latest value of 0.84. Had PSMA PET Scan March 5, 2024
After DX in November 2018 with Stage IV and Gleason of 5+4 and 4+5, and 5 years of ADT of Lupron (then Orgovyx), prednisone 5mg, and Zytiga 250mg with low fat breakfast, my PSA stayed stable at 0.4 or 0.5. At end of 2013, PSA started rising to latest value of 0.84. Had PSMA PET Scan March 5, 2024
JazzMan42
in
Advanced Prostate Cancer
6 months ago
Eligard and bicalutamide.
Started eligard and bicalutamide post RP in 2018. Followed advice of urologist until 2022. New urologist took me off both after PSA of 0.01. Unfortunately, l did not receive advice about secondary effects of the above drugs-osteoporosis etc. A DEXA scan in 2022 revealed high possibility of bone fractures
Started eligard and bicalutamide post RP in 2018. Followed advice of urologist until 2022. New urologist took me off both after PSA of 0.01. Unfortunately, l did not receive advice about secondary effects of the above drugs-osteoporosis etc. A DEXA scan in 2022 revealed high possibility of bone fractures
edgeh
in
Advanced Prostate Cancer
6 months ago
Degarelix worked for 6 months now on xtandi as well.
Degarelix worked for 6 months now on xtandi as well gleeson score 8 psa has fallen slightly from 323 to 280 how long should i expect xtandi to stop bone pain etc.
Degarelix worked for 6 months now on xtandi as well gleeson score 8 psa has fallen slightly from 323 to 280 how long should i expect xtandi to stop bone pain etc.
littlemount
in
Advanced Prostate Cancer
6 months ago
PSA rising after salvage treatment
Hi, It's been a while since I was on this forum, but I am in need of some advice. I had a radical prostatectomy in 2021 followed by salvage radio therapy. My psa levels have been rising slowly since then and I wondered if there was any advice as to what it might mean and if there is anything I should
Hi, It's been a while since I was on this forum, but I am in need of some advice. I had a radical prostatectomy in 2021 followed by salvage radio therapy. My psa levels have been rising slowly since then and I wondered if there was any advice as to what it might mean and if there is anything I should
MotoGuzziFan
in
Prostate Cancer Network
6 months ago
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