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Please help us decide on next treatment
Hi, my Dad was diagnosed back in 2021 with stage IV, Gleason 9, oligometastatic. He had 6 weeks of radiation at the time of diagnosis and has been for the past 2.5 years on Abiraterone, Prednisone and Lupron. As I mentioned in my prior post my Dad’s PSA started going up. He had a PSMA Pet scan and it
Hi, my Dad was diagnosed back in 2021 with stage IV, Gleason 9, oligometastatic. He had 6 weeks of radiation at the time of diagnosis and has been for the past 2.5 years on Abiraterone, Prednisone and Lupron. As I mentioned in my prior post my Dad’s PSA started going up. He had a PSMA Pet scan and it
Simonapo
in
Advanced Prostate Cancer
5 months ago
Need advice on clinical trial RO7656594
I have updated our profile, but in a nutshell we've gone through abiraterone, Xtandi, docetaxel, Pluvicto , cabazitaxel and carboplatin. My husband's most recent PSA on 4/12 was 79.52. His MO has put a hold on chemo our last 3 appointments due to pancytopenia. He's received 2 blood transfusions on his
I have updated our profile, but in a nutshell we've gone through abiraterone, Xtandi, docetaxel, Pluvicto , cabazitaxel and carboplatin. My husband's most recent PSA on 4/12 was 79.52. His MO has put a hold on chemo our last 3 appointments due to pancytopenia. He's received 2 blood transfusions on his
Yadifan
in
Advanced Prostate Cancer
5 months ago
Should I Add Docetaxel to Lupron and Zytiga?
I have been on Lupron and Abiraterone for most of my almost 12 years of treatment. Triplet therapy was not SOC when I was first dx'd. I am just wondering why, Docetaxel isn't routinely added to those of us who started on doublet therapy before we become resistant to the doublet therapy. My guess is that
I have been on Lupron and Abiraterone for most of my almost 12 years of treatment. Triplet therapy was not SOC when I was first dx'd. I am just wondering why, Docetaxel isn't routinely added to those of us who started on doublet therapy before we become resistant to the doublet therapy. My guess is that
jfoesq
in
Advanced Prostate Cancer
5 months ago
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Just some good news
Just wanted to update you all on this in case anyone is thinking of surgery to fix something non-cancer related. My husband was looking into getting a hip replacement back in 2021 when he was diagnosed with PC. So the hip replacement was put on hold,. But the hip arthritis kept getting worse and he
Just wanted to update you all on this in case anyone is thinking of surgery to fix something non-cancer related. My husband was looking into getting a hip replacement back in 2021 when he was diagnosed with PC. So the hip replacement was put on hold,. But the hip arthritis kept getting worse and he
Bspouse
in
Advanced Prostate Cancer
5 months ago
My prostate history
In 2020 at age 66 years I was diagnosed with prostate cancer. DRE was negative. TRUS Prostate biopsy positive: Gleason score 7 (3+4) left lateral base, Gleason score 6 (3+3) left lateral apex. Treatment plan: Active Surveillance. In February 2024, Rise in PSA 12.8, compared to 5.8 six months earlier
In 2020 at age 66 years I was diagnosed with prostate cancer. DRE was negative. TRUS Prostate biopsy positive: Gleason score 7 (3+4) left lateral base, Gleason score 6 (3+3) left lateral apex. Treatment plan: Active Surveillance. In February 2024, Rise in PSA 12.8, compared to 5.8 six months earlier
BobDad
in
Prostate Cancer Network
5 months ago
Nagalase count
My nagalase count is declining. 1.55 -1.37 - 1.12 today. The Clioquinol +zinc +ivermicetin is still working on the way to zero. PSA is steady at 32 Nagalase is an enzyme that cancer cells produce to protect themselves from the immune system.
My nagalase count is declining. 1.55 -1.37 - 1.12 today. The Clioquinol +zinc +ivermicetin is still working on the way to zero. PSA is steady at 32 Nagalase is an enzyme that cancer cells produce to protect themselves from the immune system.
agnut
in
Fight Prostate Cancer
5 months ago
Side effects from Xtandi monotherapy?
after failing multiple times on regular ADT plus SBRT and finally failing LU– 177 and Provenge, my PSA went on the rise again. I’ve been on mono Xtando for six weeks and not feeling well despite trying to exercise heavily. Going in for bloodwork tomorrow. What kind of labs should I ask for? Anyone
after failing multiple times on regular ADT plus SBRT and finally failing LU– 177 and Provenge, my PSA went on the rise again. I’ve been on mono Xtando for six weeks and not feeling well despite trying to exercise heavily. Going in for bloodwork tomorrow. What kind of labs should I ask for? Anyone
SViking
in
Advanced Prostate Cancer
5 months ago
What is Your Opinion on Docetaxel Added to Doublet Therapy for Early Oligorecurrent Metaststic M1a Prostate Cancer?
Hello, I have touched on this subject before, but it is something that is nagging at me and giving me some sleepless nights. My husband’s bio is updated for reference. At one year post prostatectomy with Stage 3b, he rose from 0.06 to 0.273 in three mos. At psa of 0.16 , a PSMA scan showed three sub
Hello, I have touched on this subject before, but it is something that is nagging at me and giving me some sleepless nights. My husband’s bio is updated for reference. At one year post prostatectomy with Stage 3b, he rose from 0.06 to 0.273 in three mos. At psa of 0.16 , a PSMA scan showed three sub
103532
in
Advanced Prostate Cancer
5 months ago
another undetectable
PSA in again at undetectable which I am assuming means my testosterone is not recovering . No T result yet but 0.5 last month! Still on Apalutamide as a monotherapy but coming off that too is bouncing around my head. Would love to go med free, still watching all developments and still no idea of the
PSA in again at undetectable which I am assuming means my testosterone is not recovering . No T result yet but 0.5 last month! Still on Apalutamide as a monotherapy but coming off that too is bouncing around my head. Would love to go med free, still watching all developments and still no idea of the
Brysonal
in
Fight Prostate Cancer
5 months ago
Opinions on my 2nd MRI results
Hello, I just received the results from 2nd MRI (results below and photos in reply), previous one was from Jan/2023 (results in bio). Having been on these forums for almost two years now, and in AS at UCLA, I highly value the opinion of those here that have similar experiences to my situation. Questions
Hello, I just received the results from 2nd MRI (results below and photos in reply), previous one was from Jan/2023 (results in bio). Having been on these forums for almost two years now, and in AS at UCLA, I highly value the opinion of those here that have similar experiences to my situation. Questions
Maximode
in
Prostate Cancer Network
5 months ago
Prostate cancer radiotherapy side effects.
I’m a seventy seven year old who had a radical prostatectomy eight years ago. Following one of my regular PSA tests the result showed, after scans in September 2023, a return in the prostate bed and adjacent lymph nodes. Began hormone implants straight away followed by twenty doses of targeted radiotherapy
I’m a seventy seven year old who had a radical prostatectomy eight years ago. Following one of my regular PSA tests the result showed, after scans in September 2023, a return in the prostate bed and adjacent lymph nodes. Began hormone implants straight away followed by twenty doses of targeted radiotherapy
Gingerurgent
in
Pelvic Radiation Disease Association
5 months ago
When is PARP introduced?
Hi My husband is currently on triple therapy ( Docetaxel chemo , Zoladex every 3 months and nubeqa) he has one more chemo round left next week. He is responding well so far as PSA is declining ( see profile for PSA) . I have seen some men are talking a PARP inhibitor and nubeqa and zoladex ( or ADT
Hi My husband is currently on triple therapy ( Docetaxel chemo , Zoladex every 3 months and nubeqa) he has one more chemo round left next week. He is responding well so far as PSA is declining ( see profile for PSA) . I have seen some men are talking a PARP inhibitor and nubeqa and zoladex ( or ADT
positive-thinking
in
Advanced Prostate Cancer
5 months ago
herbicide and recurrence
I'm looking for scientific evidence on herbicide exposure and cancer recurrence. Background: My condo association wants to spray my lawn with herbicide. (2-4-d & dicamba; thankfully not glyphosate--at least not yet) I've asked them not to and suggested safer alternatives. They say I'm being a PIA
I'm looking for scientific evidence on herbicide exposure and cancer recurrence. Background: My condo association wants to spray my lawn with herbicide. (2-4-d & dicamba; thankfully not glyphosate--at least not yet) I've asked them not to and suggested safer alternatives. They say I'm being a PIA
mistersafety
in
Advanced Prostate Cancer
5 months ago
salvage radiation after surgery?
Hi - Shouldn’t I be doing salvage radiation or chemotherapy now? I had my surgery February 25 and Doctor wants to wait for first PSA iat end of May. However surgical pathology showed negative margins but showed intraductal, cribriform, loss of PTEN. and PNI. Even though there was no EPE, no SVI, No LVI
Hi - Shouldn’t I be doing salvage radiation or chemotherapy now? I had my surgery February 25 and Doctor wants to wait for first PSA iat end of May. However surgical pathology showed negative margins but showed intraductal, cribriform, loss of PTEN. and PNI. Even though there was no EPE, no SVI, No LVI
Granolaberry
in
Prostate Cancer Network
5 months ago
What should your resting heart rate be?
From the podcast from Dr. John Day (https://drjohnday.com) , with the title:
"What Should Your Resting Heart Rate Be?
If you consult online with the Mayo Clinic, they will tell you that a normal resting heart rate is 60 to 100 bpm. While this may be a typical resting heart rate, it is certainly
From the podcast from Dr. John Day (https://drjohnday.com) , with the title:
"What Should Your Resting Heart Rate Be?
If you consult online with the Mayo Clinic, they will tell you that a normal resting heart rate is 60 to 100 bpm. While this may be a typical resting heart rate, it is certainly
Hidden
in
AF Association
1 year ago
stopping Abiratrerone
I was diagnosed with PC in Jan 2001 with Gleason of 4+ and a PSA that never got above 10. From a PSMA scan, I have bone metasteses in skull, ribs, backbone, hips, pelvic bone. WE believe that in my case PSA has never been a very useful measure. I have been taking Abiraterone, Prostap and prednisolone
I was diagnosed with PC in Jan 2001 with Gleason of 4+ and a PSA that never got above 10. From a PSMA scan, I have bone metasteses in skull, ribs, backbone, hips, pelvic bone. WE believe that in my case PSA has never been a very useful measure. I have been taking Abiraterone, Prostap and prednisolone
Stephen399b
in
Advanced Prostate Cancer
5 months ago
Radiation 10+ years after initial imrt
Psma detected a small area of cancer in what is left of my prostate…..psa of 20 at that time. After 3 months of eligard ,abiraterone and prednisone dropped to 0.04. MO and local radiologic oncologist are recommending a consult at MSK for tx of this area by whatever means might be the most safe and
Psma detected a small area of cancer in what is left of my prostate…..psa of 20 at that time. After 3 months of eligard ,abiraterone and prednisone dropped to 0.04. MO and local radiologic oncologist are recommending a consult at MSK for tx of this area by whatever means might be the most safe and
Tommyj2
in
Advanced Prostate Cancer
5 months ago
Cause for concern?
Would you please comment on the following article which may mean a new PET scan is required I'm my case? ( I Hope not!!) Extract from a recent article which is double Dutch to me!!! "...... Ignorant/lazy docs only take notice of the PSA, when it is widely known that at low PSA PSADT is equally, if not
Would you please comment on the following article which may mean a new PET scan is required I'm my case? ( I Hope not!!) Extract from a recent article which is double Dutch to me!!! "...... Ignorant/lazy docs only take notice of the PSA, when it is widely known that at low PSA PSADT is equally, if not
m1946
in
Prostate Cancer Network
5 months ago
Pluvicto+Xtandi Delays Progression Better than Xtandi-alone in mCRPC
Significant improvement in progression-free survival, PSA, and pain scores. Side effects were fatigue, nausea and dry mouth. https://www.prostatecancer.news/2024/04/pluvictoxtandi-delays-progression.html
Significant improvement in progression-free survival, PSA, and pain scores. Side effects were fatigue, nausea and dry mouth. https://www.prostatecancer.news/2024/04/pluvictoxtandi-delays-progression.html
Tall_Allen
in
Advanced Prostate Cancer
5 months ago
Treatment
My dears, after RP (Gleason 7, 4+3, infected 3 lymph nodes) and lymphadetectomy, radiation and hormone therapy for 39 months, my oncologist took me off hormone therapy with the recommendation of PSA control every 3 months. The last three PSA readings (every three months) were 0.01 / 0.00 / 0.00, I expect
My dears, after RP (Gleason 7, 4+3, infected 3 lymph nodes) and lymphadetectomy, radiation and hormone therapy for 39 months, my oncologist took me off hormone therapy with the recommendation of PSA control every 3 months. The last three PSA readings (every three months) were 0.01 / 0.00 / 0.00, I expect
adam1967adam
in
Advanced Prostate Cancer
5 months ago
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