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which is the better treatment for osteoporosis for post menopausal woman of 78 years?
Which is the best treatment for post menopausal woman of 78 years : a) Prolia (
denosumab
injection) or b) Aclasta (zolendronic acid) ? smtkrgsl (son)
Which is the best treatment for post menopausal woman of 78 years : a) Prolia (
denosumab
injection) or b) Aclasta (zolendronic acid) ? smtkrgsl (son)
smtamt
in
Osteoporosis Support
5 years ago
Approved Treatments for Triple Negative MBC Patients
Patients with bone metastases should receive a bone-directed therapy such as Xgeva (
Denosumab
) or Zometa (Zoledronic acid) in addition to their other therapy.
Patients with bone metastases should receive a bone-directed therapy such as Xgeva (
Denosumab
) or Zometa (Zoledronic acid) in addition to their other therapy.
Bestbird
in
SHARE Metastatic Breast Cancer
5 years ago
FDA-Approved Treatments for HER2+, Hormone Receptor Negative Patients
Patients with bone metastases should receive a bone-directed therapy such as Xgeva (
Denosumab
) or Zometa (Zoledronic acid) in addition to their other therapy.
Patients with bone metastases should receive a bone-directed therapy such as Xgeva (
Denosumab
) or Zometa (Zoledronic acid) in addition to their other therapy.
Bestbird
in
SHARE Metastatic Breast Cancer
5 years ago
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Approved Therapies for Triple Positive (HR+, HER2+) MBC Patients
Patients with bone metastases should receive a bone-directed therapy such as Xgeva (
Denosumab
) or Zometa (Zoledronic acid) in addition to their other therapy.
Patients with bone metastases should receive a bone-directed therapy such as Xgeva (
Denosumab
) or Zometa (Zoledronic acid) in addition to their other therapy.
Bestbird
in
SHARE Metastatic Breast Cancer
5 years ago
A Detailed History of my PMR Journey
My doctor also prescribed an injection of Prolia (
denosumab
) every six months to avoid osteoporosis. Along the way, I developed Achilles tendinitis from an injury while exercising. I was taking 10 mg prednisone at the time and I presume the prednisone weakened my tendon.
My doctor also prescribed an injection of Prolia (
denosumab
) every six months to avoid osteoporosis. Along the way, I developed Achilles tendinitis from an injury while exercising. I was taking 10 mg prednisone at the time and I presume the prednisone weakened my tendon.
Doclew44
in
PMRGCAuk
5 years ago
FDA-Approved Treatments for HR+, HER2- Premenopausal Patients
If you have bone metastases, you should receive a bone-directed therapy such as Xgeva (
Denosumab
) or Zometa (Zoledronic acid) in addition to your other therapy.
If you have bone metastases, you should receive a bone-directed therapy such as Xgeva (
Denosumab
) or Zometa (Zoledronic acid) in addition to your other therapy.
Bestbird
in
SHARE Metastatic Breast Cancer
5 years ago
Approved Treatment Options for HR+, HER2- Postmenopausal Women
Patients with bone metastases should receive a bone-directed therapy such as Xgeva (
Denosumab
) or Zometa (Zoledronic acid) in addition to their other therapy.
Patients with bone metastases should receive a bone-directed therapy such as Xgeva (
Denosumab
) or Zometa (Zoledronic acid) in addition to their other therapy.
Bestbird
in
SHARE Metastatic Breast Cancer
5 years ago
Prolia advert
And then in the end, how she was still living her life - and the words Prolia
denosumab
on the screen. Makes me sick, but the company must be getting worried if they are flogging it on tv now. This is how they get unwitting patients to ask their doctor for a prescription.
And then in the end, how she was still living her life - and the words Prolia
denosumab
on the screen. Makes me sick, but the company must be getting worried if they are flogging it on tv now. This is how they get unwitting patients to ask their doctor for a prescription.
HeronNS
in
Bone Health and Osteoporosis UK
6 years ago
Inhibition of NFκB Reduces Prostate Cancer Related Osteoclastogenesis In Vitro and Osteolysis Ex Vivo.
{Note that
Denosumab
[Xgeva] is also a RANKL inhibitor.}
{Note that
Denosumab
[Xgeva] is also a RANKL inhibitor.}
pjoshea13
in
Advanced Prostate Cancer
6 years ago
I'm new here - Denosumab?
The
Denosumab
in particular seems like a risk too far at the moment having read about people with serious long term bad effects, increased risk of fractures if you come off it, possible jaw problems etc etc...
The
Denosumab
in particular seems like a risk too far at the moment having read about people with serious long term bad effects, increased risk of fractures if you come off it, possible jaw problems etc etc...
LouisaMay
in
SHARE Metastatic Breast Cancer
6 years ago
Denosumab/Xgeva
I’m just about to have my first bone strengthening injection and have just read the side effects. Now I am terrified. Have to leave in 1hr. Has anyone had a bad reaction to it? Do I really need it?
I’m just about to have my first bone strengthening injection and have just read the side effects. Now I am terrified. Have to leave in 1hr. Has anyone had a bad reaction to it? Do I really need it?
Toomanyquestions
in
SHARE Metastatic Breast Cancer
6 years ago
Prednisone to Blame for ERA 223 Trial Failure?
“However, if deemed necessary by the clinicians, concomitant administration of bone resorption inhibitors (
denosumab
and bisphosphonates) are needed to counteract the increased risk of fragility skeletal fractures.”
“However, if deemed necessary by the clinicians, concomitant administration of bone resorption inhibitors (
denosumab
and bisphosphonates) are needed to counteract the increased risk of fragility skeletal fractures.”
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Question for men on Denosumab (Xgeva)
Has anyone here on
denosumab
experienced the rare side effect of atypical femoral fracture? I’ve had mets at the top of my right femur for some time, and there’s rarely been pain. This week’s bone scan shows the mets creeping downward about to the center of the femur.
Has anyone here on
denosumab
experienced the rare side effect of atypical femoral fracture? I’ve had mets at the top of my right femur for some time, and there’s rarely been pain. This week’s bone scan shows the mets creeping downward about to the center of the femur.
YostConner
in
Advanced Prostate Cancer
6 years ago
Bisphosphonates & Prolia -- DANGEROUS
The new line of drugs are called
Denosumab
(of which Prolia is very popular). Arguebly, the new drugs are worse because they go upstream and suppress precursor proteins such as something called RANKL or RANK ligand -- which has many functions other than just activating osteoclasts.
The new line of drugs are called
Denosumab
(of which Prolia is very popular). Arguebly, the new drugs are worse because they go upstream and suppress precursor proteins such as something called RANKL or RANK ligand -- which has many functions other than just activating osteoclasts.
SandyABC
in
Bone Health and Osteoporosis UK
6 years ago
No meds can help - ANY FURTHER OPTIONS - please?
As far as I know there are only bisphosphonates,
denosumab
and parathyroid. It infuriates me that patients aren't WARNED about the "drug prison" you end up in when you take Prolia. You can never go off it, once you take it. I am very angry.
As far as I know there are only bisphosphonates,
denosumab
and parathyroid. It infuriates me that patients aren't WARNED about the "drug prison" you end up in when you take Prolia. You can never go off it, once you take it. I am very angry.
DianeBM
in
Bone Health and Osteoporosis UK
6 years ago
Xgeva / calcium & vitamin D.
Severe hypocalcaemia is a rare and dangerous side effect of
denosumab
. We present a case of a patient with metastatic prostate cancer who developed severe hypocalcaemia after receiving a single dose of
denosumab
.
Severe hypocalcaemia is a rare and dangerous side effect of
denosumab
. We present a case of a patient with metastatic prostate cancer who developed severe hypocalcaemia after receiving a single dose of
denosumab
.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Medication for bone mets
In 2 weeks I start
denosumab
(prolia) because of bone Mets. This is really frightening me, esp. Jaw risks. How did others find it?
In 2 weeks I start
denosumab
(prolia) because of bone Mets. This is really frightening me, esp. Jaw risks. How did others find it?
Rotagirl
in
SHARE Metastatic Breast Cancer
6 years ago
Parkinsons and Osteoporosis medications
This time they suggest a 6 monthly injection of something called
denosumab
. Does anyone else here juggle with these two conditions? I take Madopar for Parkinsons, which works well for me, and am reluctant to possibly complicate things with other medication.
This time they suggest a 6 monthly injection of something called
denosumab
. Does anyone else here juggle with these two conditions? I take Madopar for Parkinsons, which works well for me, and am reluctant to possibly complicate things with other medication.
ge1shh
in
Cure Parkinson's
6 years ago
Stopping Denosumab Prolia
It was not until September The European Medicines Agency (EMA) revised their advice – patients either being offered alterative medication or to continue with
denosumab
. Posy White
It was not until September The European Medicines Agency (EMA) revised their advice – patients either being offered alterative medication or to continue with
denosumab
. Posy White
Posy-White
in
Bone Health and Osteoporosis UK
6 years ago
Bloody nose
I started on Ibrance 125mg, letrozole and
denosumab
injections three weeks ago. Apart from a woolly head and aches and pains this is the only other side effect.
I started on Ibrance 125mg, letrozole and
denosumab
injections three weeks ago. Apart from a woolly head and aches and pains this is the only other side effect.
StE72
in
SHARE Metastatic Breast Cancer
6 years ago
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