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the DARE trial....anyone familiar with it, been in it?
the trial is ongoing screening of your blood every 6 months, checking for ctDNA ( cancer tumor DNA)....if it is found you begin a treatment regimen...if not they just continue to screen you for 2 years...any thoughts? In my mind this should be the future of cancer detection as it finds the disease at
the trial is ongoing screening of your blood every 6 months, checking for ctDNA ( cancer tumor DNA)....if it is found you begin a treatment regimen...if not they just continue to screen you for 2 years...any thoughts? In my mind this should be the future of cancer detection as it finds the disease at
Drrob81
in
SHARE Metastatic Breast Cancer
8 months ago
Experiences with securing ss and private disability
Hello, Silent observor here, wife to Ed: Diagnosed with stage IV, Gleason 8, November 2020, with mets to nearby lymph nodes and lungs (of all places). Successfully treated so far with orchiectomy, Zytiga and prednisone with minimum SE. Age 60, living in PNW of US. Ed is considering an application
Hello, Silent observor here, wife to Ed: Diagnosed with stage IV, Gleason 8, November 2020, with mets to nearby lymph nodes and lungs (of all places). Successfully treated so far with orchiectomy, Zytiga and prednisone with minimum SE. Age 60, living in PNW of US. Ed is considering an application
MIkamom
in
Advanced Prostate Cancer
5 months ago
Lots of Blood in stool. Could it be colon cancer or colorectal cancer? WARNING: *graphic content*
HelloIn past couple days ago, i have a minor diarreah and poops normally ( normal brown color ) but last night, i went to thr bathroom and there's blood in stools and clots, ans slightly burns ( i ate spicy foods ). I panicked and cried. This is my second time it happened. I remember last year, on
HelloIn past couple days ago, i have a minor diarreah and poops normally ( normal brown color ) but last night, i went to thr bathroom and there's blood in stools and clots, ans slightly burns ( i ate spicy foods ). I panicked and cried. This is my second time it happened. I remember last year, on
Jesusismysaviour
in
Colon Cancer Connected
1 year ago
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Provenge (only) - impact on overall survival
I just got insurance approval for Provenge...out of pocket is really high so now I'm doing a cost benefit analysis in my mind. I've seen many different articles showing that Provenge ALONE only extends overall survival by 4-15 months. Does that sound correct? Tall_Allen mentioned adding xofigio for
I just got insurance approval for Provenge...out of pocket is really high so now I'm doing a cost benefit analysis in my mind. I've seen many different articles showing that Provenge ALONE only extends overall survival by 4-15 months. Does that sound correct? Tall_Allen mentioned adding xofigio for
Gl448
in
Advanced Prostate Cancer
8 months ago
Mistery therapy: Gastrin-releasing peptide receptors s target for PCa
I will have to dig deeper to find the 4 clinical trials mentioned, but here is the text "Each tumor has its own distinctive molecular identity. Treatment, therefore, should be tailored to this unique cancer phenotype. Theragnostics uses the same compound for targeted imaging and treatment, radiolabeled
I will have to dig deeper to find the 4 clinical trials mentioned, but here is the text "Each tumor has its own distinctive molecular identity. Treatment, therefore, should be tailored to this unique cancer phenotype. Theragnostics uses the same compound for targeted imaging and treatment, radiolabeled
Maxone73
in
Advanced Prostate Cancer
5 months ago
To Chemo or Not to Chemo--that is the ?
Should I follow my MO's advice and do docetaxel? Since I'm now 78, and have read terrible accounts of chemo, I have held onto the belief that I would do everything to avoid chemo since the treatment appears to be worse than the alternative. But she's really not giving me an alternative, other than
Should I follow my MO's advice and do docetaxel? Since I'm now 78, and have read terrible accounts of chemo, I have held onto the belief that I would do everything to avoid chemo since the treatment appears to be worse than the alternative. But she's really not giving me an alternative, other than
LifeQuality
in
Advanced Prostate Cancer
8 months ago
Chemotherapy holiday
Good morning to all! I was diagnosed stage 4 mbc, er+, pr+, her2 low to+, 2 years ago. I also found out last summer I have the PIK3 mutation...not much luck with treatments. So far matastases have remained in bones. Was on Kinjinti, Femara, Faslodex for a few months, then Femara was withdrawn..kep the
Good morning to all! I was diagnosed stage 4 mbc, er+, pr+, her2 low to+, 2 years ago. I also found out last summer I have the PIK3 mutation...not much luck with treatments. So far matastases have remained in bones. Was on Kinjinti, Femara, Faslodex for a few months, then Femara was withdrawn..kep the
Tuckermom
in
SHARE Metastatic Breast Cancer
5 months ago
Testosterone and adrenal glands
Hello all, so I finished 10 rounds of chemo docetaxel last year in September. My PSA was down to 2.8 Oct 5th. I had an orchiectomy Oct 15. My PSA started to rise. Nov 5th PSA 5.15. Dec 6th PSA 7.85. Jan 11 PSA 16.23 I have had CT and bone scan early October and another set of scans early January
Hello all, so I finished 10 rounds of chemo docetaxel last year in September. My PSA was down to 2.8 Oct 5th. I had an orchiectomy Oct 15. My PSA started to rise. Nov 5th PSA 5.15. Dec 6th PSA 7.85. Jan 11 PSA 16.23 I have had CT and bone scan early October and another set of scans early January
Eugmn
in
Advanced Prostate Cancer
8 months ago
Barry
Hi, Diagnosed with advanced prostate cancer gleeson score 4+4, psa level 77, about 10 months ago on testosterone injections every 6 months (degarelix) , wondering how long i can go on like this before cancer comes back to bones and what will be my options then, can you survive for many years on just
Hi, Diagnosed with advanced prostate cancer gleeson score 4+4, psa level 77, about 10 months ago on testosterone injections every 6 months (degarelix) , wondering how long i can go on like this before cancer comes back to bones and what will be my options then, can you survive for many years on just
littlemount
in
Advanced Prostate Cancer
8 months ago
PCA Cure and when?
7 months into my fight against castration sensitive prostate cancer. PSA is 0 on ADT and Abiraterone and methylprednisolone. Averaged 8,600 steps/day. I have just started to add occasional sprinting. I am taking multiple supplements. I am greatful that my PSA is 0. I work everyday and pray for
7 months into my fight against castration sensitive prostate cancer. PSA is 0 on ADT and Abiraterone and methylprednisolone. Averaged 8,600 steps/day. I have just started to add occasional sprinting. I am taking multiple supplements. I am greatful that my PSA is 0. I work everyday and pray for
Nowhereman9
in
Advanced Prostate Cancer
8 months ago
The MAO inhibitors phenelzine and clorgyline revert enzalutamide resistance in castration resistant prostate cancer
I am not using enza (yet) wondering if it's worth taking some nutmeg to keep those mao in check anyway! :-P https://www.nature.com/articles/s41467-020-15396-5
I am not using enza (yet) wondering if it's worth taking some nutmeg to keep those mao in check anyway! :-P https://www.nature.com/articles/s41467-020-15396-5
Maxone73
in
Fight Prostate Cancer
8 months ago
Skull Metastasis
I just received an order for a brain M RI from Dr. Aggarwal. I was wondering why. My recent PSMA PET scan an d probably confirmed by SPECT scans after Pluvicto show bone metastasis in my skull as well as in other bones (one of which has an SUV of 38) and which was quite painful before Pluvicto but has
I just received an order for a brain M RI from Dr. Aggarwal. I was wondering why. My recent PSMA PET scan an d probably confirmed by SPECT scans after Pluvicto show bone metastasis in my skull as well as in other bones (one of which has an SUV of 38) and which was quite painful before Pluvicto but has
spencoid2
in
Advanced Prostate Cancer
8 months ago
Advanced Prostate Cancer
I have Advanced prostate cancer. Prostate removed, radiation, lupron for the last 4 years, Now I am on abiraterone with the lupron, because PSA was up . See Dr in Feb to see if PSA is stable Is anyone else on the 2 drugs Thank you Mark
I have Advanced prostate cancer. Prostate removed, radiation, lupron for the last 4 years, Now I am on abiraterone with the lupron, because PSA was up . See Dr in Feb to see if PSA is stable Is anyone else on the 2 drugs Thank you Mark
Retrievertrainer
in
Advanced Prostate Cancer
8 months ago
FDA approval Alecensa (alectinib) following surgery for people with early stage ALK positive NSCLC
On April 18, 2024, the U.S. Food and Drug Administration (FDA) approved Alecensa (alectinib) following surgical resection for people living with early-stage ALK-positive non-small cell lung cancer (NSCLC). The approval is based on results from the ALINA study (NCT03456076). Participants with stage
On April 18, 2024, the U.S. Food and Drug Administration (FDA) approved Alecensa (alectinib) following surgical resection for people living with early-stage ALK-positive non-small cell lung cancer (NSCLC). The approval is based on results from the ALINA study (NCT03456076). Participants with stage
Miranda_GO2
Partner
in
Lung Cancer Support
5 months ago
Hospice
Sharing that my daughter and I are meeting with hospice for in home hospice care this afternoon. I was going to wait for one more CT scan and oncologist visit, but this past weekend I spent the whole weekend in bed and had so much weakness and breathing problems that I can't put it off any longer.
Sharing that my daughter and I are meeting with hospice for in home hospice care this afternoon. I was going to wait for one more CT scan and oncologist visit, but this past weekend I spent the whole weekend in bed and had so much weakness and breathing problems that I can't put it off any longer.
NPmary
in
SHARE Metastatic Breast Cancer
5 months ago
Finally diagnosed after twenty years!
I have finally got a diagnosis of IBS after at least twenty years of endoscopies, colonoscopies, scans, investigations, etc, etc. Strangely I feel much better even though they say it's a lifelong condition with no cure. My problem today is that it's after half past six in the evening, I have had one
I have finally got a diagnosis of IBS after at least twenty years of endoscopies, colonoscopies, scans, investigations, etc, etc. Strangely I feel much better even though they say it's a lifelong condition with no cure. My problem today is that it's after half past six in the evening, I have had one
Merry_Widow
in
IBS Network
8 months ago
Do you that have had Orchiectomy still take ATD Medication?
I’ve been told that I will be on ATD meds for life, I’m 63 and have been taking Lupron and Zytiga for going on two years. I asked my MO about Orchiectomy and he said if I did it he would still recommend Lupron. Can you guys please share your thoughts and experiences? Thank you in advance
I’ve been told that I will be on ATD meds for life, I’m 63 and have been taking Lupron and Zytiga for going on two years. I asked my MO about Orchiectomy and he said if I did it he would still recommend Lupron. Can you guys please share your thoughts and experiences? Thank you in advance
OldGuysRule
in
Advanced Prostate Cancer
8 months ago
BCF after 9 years post proton therapy
My PSA had been increasing slowly since my nadir of .75 in 2017 reaching 1.19 in 2022. Both RO and Uro weren't terribly concerned. I wanted PSMA after 3rd consecutive increase but both recommended a wait and see approach, especially the RO who seems honor bound to wait for 2.0 over nadir. I skipped
My PSA had been increasing slowly since my nadir of .75 in 2017 reaching 1.19 in 2022. Both RO and Uro weren't terribly concerned. I wanted PSMA after 3rd consecutive increase but both recommended a wait and see approach, especially the RO who seems honor bound to wait for 2.0 over nadir. I skipped
hwrjr
in
Prostate Cancer Network
8 months ago
HoLEP Affect on Pca
as posted earlier, I have both BPH (80 cc) and localized prostate cancer. Clear PSMA. I’m having HoLEP surgery. Wonder how this will impact the cancer. How will PSA respond? What happens if HoLEP actually removed the cancer?
as posted earlier, I have both BPH (80 cc) and localized prostate cancer. Clear PSMA. I’m having HoLEP surgery. Wonder how this will impact the cancer. How will PSA respond? What happens if HoLEP actually removed the cancer?
Bourbon2024
in
Prostate Cancer Network
8 months ago
High risk vs. aggressive cancer
I understand the definition of high-risk prostate cancer (Gleason, PSA and/or spread), but that doesn't necessarily seem to be the same thing as aggressive cancer. How can aggressiveness be determined for high risk, localized cancer? Thanks for any insight and information.
I understand the definition of high-risk prostate cancer (Gleason, PSA and/or spread), but that doesn't necessarily seem to be the same thing as aggressive cancer. How can aggressiveness be determined for high risk, localized cancer? Thanks for any insight and information.
RugbyVLS
in
Advanced Prostate Cancer
7 months ago
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