Experiences with

Chronic leukaemia

Hi all. I am very new to this platform but so grateful to have a place to ask some difficult questions to people who may understand. I have just started humira after reacting badly to mabthera. I have also previously been on methotrexate, azaoress, nivaquin abd high dose steroids to name a few. I have

The computer model, developed under the lead management of researchers at TU Graz, simulates the cyclical changes in the membrane potential of a cancer cell using the example of human lung adenocarcinoma and opens up completely new avenues in cancer research. Computer models have been standard tools

Hi I'm 1 year post liver transplant, but my kidneys seem to be taking a hit. My GFR is reducing at each blood test. It is now 39 and drops by about 5 every time. They've not said if it's now CKD but I'm worried as the internet says 39 is stage 3B. They have reduced my tacrolimus to 1mg twice daily,

Was diagnosed with CLL in 2018 at 45yrs old, started treatment in 2019 and just finished my 19th month of Obinituzamab, Venetoclax, and Ibrutinib trial. Had BMB and showed remaining small population of B-cells - dang! Also showed Trisomy 8? Seems very rare for CLL patient to have Trisomy 8. Oncologist

Cambridge scientists have identified 200 approved drugs predicted to work against COVID-19—of which only 40 are currently being tested in COVID-19 clinical trials. In a study published today in Science Advances, a team led by researchers at the University of Cambridge’s Milner Therapeutics Institute

I have had faint positives on FRER for 72h (since PM d5p5dt) that are getting slowly darker and pinker but remaining quite pencil like. Last night I had a faint positive on a clear blue for the first time. But today I’ve done a dumb thing and got my hcg tested, 3 days before OTD 🤦🏻‍♀️. It’s really

Dr Munir’s main clinical and research special interests are in chronic lymphocytic leukaemia, particularly in the assessment of the mechanism of action of novel targeted therapies. • Lianne Palmer, CLL-specific CNS at Oxford University Hospitals.

i got 2100+ HCG at 15dp6dt. today is 17dp6dt now booked for another two weeks wait for the scan. I am super nervous. my heartbeat is so fast. all negative thoughts are coming over my mind. I don't know what should I do? This wait becomes very hard for me.

Our first joint webinar! 31 May 6.30 pm - 8.00 pm London (1.30 pm EST) We are very pleased to announce our first joint webinar with CLL Ireland. We are privileged to have as our keynote speakers Dr Brian Koffman, founder and principal of the CLL Society, and Professor Patrick Thornton, Consultant

Hey lovley ladies xx So I'm 6. 3 weeks pregnant I had my beta HCG on the 23rd it came back as low at 66, did a repeat the nurse said congratulations your beta rose to 227 so a good increase and something to calm the worry for probably an hour before I realised I have the dreaded scan to look forward

387.87 beta hcg value at day 12 of FET... Is it a good one? Having bloating and pressure in lower pelvis area.. Constipated🙄

Mon Jun 28, 2021 9:18 pm Hello MPNers Since my last post I left hospital but after 10 days 5 days at my parents house till my kids got over sniffles and 5 days at home my liver function deranged significantly again so I was readmitted to Westmead Public Hospital. Today is day 22 of my stay back at hospital

Is this good? 2nd blood test on Monday

lymphoid leukaemia, myeloma, Waldenstrom’s macroglobulinemia and other plasma cell dyscrasias (note: this list is not exhaustive) immunosuppression due to HIV/AIDS with a current CD4 count of <200 cells/µl for adults or children primary or acquired cellular and combined immune deficiencies – those with

I started Jakavi treatment some months ago as I was progressing from PV to myelofibrosis. I had immediate relief from itching but it seems to have returned. Enlsrged spleen, haematocrit down, platelets low and white cells not well controlled. What now?

Hi all! My drs are suggesting to put me on tacrolimus alongside AZA to help with my joint pain. Has anyone been on tacrolimus? With or without AZA or another immunosuppressant? How is your experience? Anyone have any knowledge/experience of long-term tacrolimus? Also, I got told by the nurse

«  Of great interest, a set of epigenetic mutations can co-exist with the phenotypic driver mutations in 35%–40% of MPNs. These epigenetic mutations, such as TET2, EZH2, ASXL1, or DNMT3A mutations, promote clonal hematopoiesis and increased fitness of aged hematopoietic stem cells in both clonal hematopoiesis

Cordyceps worm mold is widely used in China to treat kidney disease, and some scientific studies indicate that it may reduce creatinine values in patients with chronic kidney disease. I have never found found much personal benefit from it. Conclusions of recent Chinese study: "Current evidence shows

Sometimes I can't help to think if enough is being done for MPN sufferers. According to multiple research ropeg has shown superiority over hydroxyurea with Ultimate possible significant molecular response in a selective number of MNP patients. So why there's a delay in getting access

My sister was diagnosed in October with cml after she said she needed some blood work done from feeling unwell. She has developed a mutation that is resistant to most treatments. She is going down hill. Someone please answer my question. 1 year prior to her Lukiema she randomly had both retinas detached