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Newly discovered stem cell offers clues to a cancer mystery.
https://www.scientificamerican.com/article/newfound-stem-cell-might-explain-how-breast-cancer-spreads-to-the-spine/#:~:text=Scientists%20have%20discovered%20a%20new,the%20reasons%20have%20been%20unknown When breast, lung and prostate cancers metastasize to multiple bones in the body, three to five
https://www.scientificamerican.com/article/newfound-stem-cell-might-explain-how-breast-cancer-spreads-to-the-spine/#:~:text=Scientists%20have%20discovered%20a%20new,the%20reasons%20have%20been%20unknown When breast, lung and prostate cancers metastasize to multiple bones in the body, three to five
anonymoose2
in
Advanced Prostate Cancer
6 months ago
Advice please
Due to my dads low red blood cell count his treament has been stopped his been off all meds except pain killler, now since september 2023. He was due to start radium 223 january 24 but its been postponed until his better, but how can he get better when his PSA is increasing weekly and his red bloods
Due to my dads low red blood cell count his treament has been stopped his been off all meds except pain killler, now since september 2023. He was due to start radium 223 january 24 but its been postponed until his better, but how can he get better when his PSA is increasing weekly and his red bloods
Hidden
in
Advanced Prostate Cancer
4 months ago
Hip pain - related to radiotherapy?
I had chemo/radiotherapy for anal cancer in 2015 and was given the all-clear in 2021. There have been a number of side effects since but 12 weeks ago I developed pain in my right hip at the end of a walk (keen walker). GP doesn't know what the cause is (no surprise there!), but arranged an X-ray, which
I had chemo/radiotherapy for anal cancer in 2015 and was given the all-clear in 2021. There have been a number of side effects since but 12 weeks ago I developed pain in my right hip at the end of a walk (keen walker). GP doesn't know what the cause is (no surprise there!), but arranged an X-ray, which
BlueDun
in
Pelvic Pain Support Network
4 months ago
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Genetic therapy: for solid malignancy hopefully soon
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
Maxone73
in
Advanced Prostate Cancer
6 months ago
CT and Bone Scan 2 weeks after PSMA PET?
Note:
for reference, my dad lives in BC, Canada. I believe the system here is a bit different than the US - we have a urologist who refers us to the RO when needed. Therefore, there is no relationship between the urologist and RO - the RO is part of the cancer institute, but the urologist is not
Note:
for reference, my dad lives in BC, Canada. I believe the system here is a bit different than the US - we have a urologist who refers us to the RO when needed. Therefore, there is no relationship between the urologist and RO - the RO is part of the cancer institute, but the urologist is not
sixmongoos
in
Advanced Prostate Cancer
7 months ago
My son’s PSA rose a bit today.
My son’s last PSA three months ago was <.01 but today it was <.10.It was previously as high as 22. He’s also tertiary five. His Mayo doctor told him to continue to test every three months, stay on current meds Lupron, Abiraterone/prednisone for another year and two months then stop meds and wait
My son’s last PSA three months ago was <.01 but today it was <.10.It was previously as high as 22. He’s also tertiary five. His Mayo doctor told him to continue to test every three months, stay on current meds Lupron, Abiraterone/prednisone for another year and two months then stop meds and wait
Cactus297
in
Advanced Prostate Cancer
7 months ago
confused about treatment options
I keep going back and forth between various treatment options. In the next week or so, I’m having appointments with a surgeon (tomorrow) and a radiation oncologist (February 6). Basic story: cancer on left side of prostate and in my pelvic lymph nodes (“hyper avid lymph node in the left external iliac
I keep going back and forth between various treatment options. In the next week or so, I’m having appointments with a surgeon (tomorrow) and a radiation oncologist (February 6). Basic story: cancer on left side of prostate and in my pelvic lymph nodes (“hyper avid lymph node in the left external iliac
Jpburns
in
Advanced Prostate Cancer
4 months ago
Avodart added to my treatment regimen. I am Leary of it.
My MO prescribed bicalutamide and avodart after my 20 rounds of SBRT. My PSA went up to 21 after the SBRT. The bicalutamide I understand. I am leary of the avodart. I am concerned that it will mask PSA rise from cancer. Any thoughts on this?
My MO prescribed bicalutamide and avodart after my 20 rounds of SBRT. My PSA went up to 21 after the SBRT. The bicalutamide I understand. I am leary of the avodart. I am concerned that it will mask PSA rise from cancer. Any thoughts on this?
Pianodude
in
Advanced Prostate Cancer
7 months ago
When's the "best" time to do the scan?
Well, it appears the salvage radiation done in January '23 (RP in 2019) may have been unsuccessful, as my latest PSA came back at 0.06, 3 months prior was 0.02. Obviously not yet actionable and not yet definitive for failure, but the indication that the barbarian hordes might be regrouping is apparent
Well, it appears the salvage radiation done in January '23 (RP in 2019) may have been unsuccessful, as my latest PSA came back at 0.06, 3 months prior was 0.02. Obviously not yet actionable and not yet definitive for failure, but the indication that the barbarian hordes might be regrouping is apparent
Cackalacky_cyclist
in
Advanced Prostate Cancer
7 months ago
Fibro my wifes diagnosis
Hi there my wife had the diagnosis yesterday fibromyalgia as she had been having pain everywhere for about 2 years My wife around 5 years ago had a tumour removed from her tummy which when the hospital removed it found it to be nearly 5 stone in weight hence why my wife felt that it was the repercussions
Hi there my wife had the diagnosis yesterday fibromyalgia as she had been having pain everywhere for about 2 years My wife around 5 years ago had a tumour removed from her tummy which when the hospital removed it found it to be nearly 5 stone in weight hence why my wife felt that it was the repercussions
Ang4john
in
Fibromyalgia Action UK
4 months ago
FDA Clearance of FK-PC101, a Novel Personalized Prostate Cancer Immunotherapy
not for stage 4 fighters...but still... "The trial, CELLVX-230, is a randomized, multicenter, open-label study of irradiated autologous cellular vaccine in men with high-risk prostate cancer post-radical prostatectomy. It will be conducted through a partnership with the Society of Urologic Oncology
not for stage 4 fighters...but still... "The trial, CELLVX-230, is a randomized, multicenter, open-label study of irradiated autologous cellular vaccine in men with high-risk prostate cancer post-radical prostatectomy. It will be conducted through a partnership with the Society of Urologic Oncology
Maxone73
in
Advanced Prostate Cancer
4 months ago
Alicia Morgans, MD, on PCa in Older Men – Determining frailty or fitness will help guide treatment decisions, MedPageToday, 11/27/2023
Those who dig deep into research methodologies know well the inherent biases that riddle much scientific and medical research. [i](See my postscript reference below) [/i]Clinical trials are not exceptions to these biases and, as drug companies look to produce the best outcomes for their clinical trials
Those who dig deep into research methodologies know well the inherent biases that riddle much scientific and medical research. [i](See my postscript reference below) [/i]Clinical trials are not exceptions to these biases and, as drug companies look to produce the best outcomes for their clinical trials
cujoe
in
Fight Prostate Cancer
6 months ago
Update on dads visit with his MO today
Took dad to his MO today, the appointment I was dreading, I was thinking they would say, were done since he has suspected LMD . This was not the case at all. His labs were all better than they have ever been, psa was 2 and kidney functions, testosterone everything was better than they have ever been
Took dad to his MO today, the appointment I was dreading, I was thinking they would say, were done since he has suspected LMD . This was not the case at all. His labs were all better than they have ever been, psa was 2 and kidney functions, testosterone everything was better than they have ever been
Radtech40
in
Advanced Prostate Cancer
4 months ago
Retzius Sparing surgeon recommendations
Hello everyone. I’m 49 years old. I was diagnosed with PCa in 2018. It was determined Gleason 3+3 after biopsy, so we decided on Active Surveillance. I checked PSA religiously every 6 months and it hovered around 5 the whole time since the diagnosis. Last year during summer I believe I started experiencing
Hello everyone. I’m 49 years old. I was diagnosed with PCa in 2018. It was determined Gleason 3+3 after biopsy, so we decided on Active Surveillance. I checked PSA religiously every 6 months and it hovered around 5 the whole time since the diagnosis. Last year during summer I believe I started experiencing
UnexpectedPC
in
Prostate Cancer Network
4 months ago
MRI Results Help Please!
Hope everyone is doing well. I got my MRI results today and was looking for help with some of the jargon please. I know there is a lady who is very good with the medical terminology. Googled serosal disease and that didn't sound good. Dr told me it's significant endo, adeno, bowl stuck to ovaries. But
Hope everyone is doing well. I got my MRI results today and was looking for help with some of the jargon please. I know there is a lady who is very good with the medical terminology. Googled serosal disease and that didn't sound good. Dr told me it's significant endo, adeno, bowl stuck to ovaries. But
DarkStar85
in
Endometriosis UK
4 months ago
asking for advice
brief synopsis Cervical cancer 1985 with surgery and radiation treatment Urostomy 1991 Artificial sphincter 2003 Urostomy revised and most of small bowel cut out because of adhesions leaving only 1.2m 2006 Colostomy formed 2007 Constant mucus from rectum In 2023 developed high inflammatory markers
brief synopsis Cervical cancer 1985 with surgery and radiation treatment Urostomy 1991 Artificial sphincter 2003 Urostomy revised and most of small bowel cut out because of adhesions leaving only 1.2m 2006 Colostomy formed 2007 Constant mucus from rectum In 2023 developed high inflammatory markers
Imakelace
in
Pelvic Pain Support Network
4 months ago
New hope for castrate resistant prostate cancer on the horizon
A new experimental drug is in development that reverses castrate resistance and makes the cancer amenable to further treatment. Early days yet but it looks interesting. https://www.theguardian.com/society/2023/oct/16/new-prostate-cancer-treatment-may-be-on-the-horizon-say-scientists
A new experimental drug is in development that reverses castrate resistance and makes the cancer amenable to further treatment. Early days yet but it looks interesting. https://www.theguardian.com/society/2023/oct/16/new-prostate-cancer-treatment-may-be-on-the-horizon-say-scientists
GeorgesCalvez
in
Advanced Prostate Cancer
7 months ago
The Science is Coming
Good to see the mini AZD5069 trial with enzalutamide offering another route to taming the beast. I am no scientist but as I understand it the target is myeloid white blood cells which can act to fuel tumours. The drup blocks the CXCR2 receptor and, in a small sample seems to have resulted in tumour shrinkage
Good to see the mini AZD5069 trial with enzalutamide offering another route to taming the beast. I am no scientist but as I understand it the target is myeloid white blood cells which can act to fuel tumours. The drup blocks the CXCR2 receptor and, in a small sample seems to have resulted in tumour shrinkage
GreenStreet
in
Prostate Cancer Network
7 months ago
FDG+/PSMA- lesions
My dad has metastatic CRPC. Xtandi failed, but at the moment he is still on it as we evaluate possible treatment options. Today we received also results of PSMA PET CT - it it stated, that there are discrepancies (loss of PSMA expression) with at least 4 bone mets when compared to findings of FDG (
My dad has metastatic CRPC. Xtandi failed, but at the moment he is still on it as we evaluate possible treatment options. Today we received also results of PSMA PET CT - it it stated, that there are discrepancies (loss of PSMA expression) with at least 4 bone mets when compared to findings of FDG (
MyDad76
in
Advanced Prostate Cancer
7 months ago
I am still struggling with treatment decisions - Help please.
I am struggling to decide on my treatment. The main point of conflict is HT or not, and LDR Brachytherapy (if I am eligible - because of a previous HOLEP) or IMRT. I also wonder if I should push hard for a 10-day earlier consultation at the risk of bad feeling. I welcome advice. In the UK - Referral
I am struggling to decide on my treatment. The main point of conflict is HT or not, and LDR Brachytherapy (if I am eligible - because of a previous HOLEP) or IMRT. I also wonder if I should push hard for a 10-day earlier consultation at the risk of bad feeling. I welcome advice. In the UK - Referral
Nordman
in
Advanced Prostate Cancer
4 months ago
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