Search
Search
About
Log in
Join
Experiences with
Besremi
Posts
Communities
370 public posts
Filter results
Not so good news - after 11 months of Besremi, WBC, RBC, Hemoglobin, and HCT were all below normal
I just had 100 mcg of
Besremi
, and it was 150 mcg for around 6 months. I will have lab test on mid-February. Best wishes to all!
I just had 100 mcg of
Besremi
, and it was 150 mcg for around 6 months. I will have lab test on mid-February. Best wishes to all!
Pat032018
in
MPN Voice
2 years ago
2nd Dose of Besremi Today
Hi, 2 weeks ago, I had my first injection of 100 mg of
Besremi
. I had a CBC done and my numbers were 'normal' HCT 42.5 and platelets 380; best I had seen in years. Talked to my specialist and she suggested I go up to 150mg this time.
Hi, 2 weeks ago, I had my first injection of 100 mg of
Besremi
. I had a CBC done and my numbers were 'normal' HCT 42.5 and platelets 380; best I had seen in years. Talked to my specialist and she suggested I go up to 150mg this time.
MrsBerri
in
MPN Voice
2 years ago
Update 7.6
I remain in a complete hematologic response at 150mcg
Besremi
. Tolerance remains the same, with mild lymphopenia, borderline neutropenia, and mild itching. I switched to Zyrtec (cetirizine) to control the itching.
I remain in a complete hematologic response at 150mcg
Besremi
. Tolerance remains the same, with mild lymphopenia, borderline neutropenia, and mild itching. I switched to Zyrtec (cetirizine) to control the itching.
hunter5582
in
MPN Voice
1 year ago
Want to take advantage of all our features? Just log in!
Log in
or
Join
My new Rux journey
Compare
Besremi
, color part of this image to the simple hexagons of Rux. Bes is a huge biological molecule. Makes IFN more satisfying, paying for all that complexity. But simplicity is always an attribute. All these are silly thoughts with no medical relevance, but it has been on my mind.
Compare
Besremi
, color part of this image to the simple hexagons of Rux. Bes is a huge biological molecule. Makes IFN more satisfying, paying for all that complexity. But simplicity is always an attribute. All these are silly thoughts with no medical relevance, but it has been on my mind.
EPguy
in
MPN Voice
1 year ago
Recombinant Interferon-β in the Treatment of Polycythemia Vera
The novel rIFN-α2b
Besremi
seems to be less toxic and perhaps also more effective than treatment with Pegasys, which is the only alternative today.
The novel rIFN-α2b
Besremi
seems to be less toxic and perhaps also more effective than treatment with Pegasys, which is the only alternative today.
Manouche
in
MPN Voice
2 years ago
MD Anderson visit
He agrees
Besremi
may treat both. But I do have bad news for our MPN world, he is retiring at the end of February. Thanks for all of your support
He agrees
Besremi
may treat both. But I do have bad news for our MPN world, he is retiring at the end of February. Thanks for all of your support
KLCTJC
in
MPN Voice
2 years ago
First dose of Besremi today (100 mg)
Hi, I'm on my way to get a routine phlebotomy and an introduction on how to self-inject
Besremi
. My prescription has me starting at 100mg. I thought it was 50, but I misread. I hope all goes well!
Hi, I'm on my way to get a routine phlebotomy and an introduction on how to self-inject
Besremi
. My prescription has me starting at 100mg. I thought it was 50, but I misread. I hope all goes well!
MrsBerri
in
MPN Voice
2 years ago
Platelet Numbers Increasing for the Better
Hi all, I wrote back a month ago worried about my lowering platelets and the doctor taking me off
Besremi
. My last injection was early November 500 mcg. My platelets got down to 53! They are coming up, now at 87, 2 weeks after the 53 reading.
Hi all, I wrote back a month ago worried about my lowering platelets and the doctor taking me off
Besremi
. My last injection was early November 500 mcg. My platelets got down to 53! They are coming up, now at 87, 2 weeks after the 53 reading.
marlenablue
in
MPN Voice
2 years ago
Low Platelets
Last spring, I got the opportunity to try
Besremi
. After 7 months, I am seeing normal white blood and red blood cell counts, hurray! But my platelet count is 53 as of today. My doctor has advised me to stop
Besremi
all together and get tested again to see if
Besremi
is causing the low platelets.
Last spring, I got the opportunity to try
Besremi
. After 7 months, I am seeing normal white blood and red blood cell counts, hurray! But my platelet count is 53 as of today. My doctor has advised me to stop
Besremi
all together and get tested again to see if
Besremi
is causing the low platelets.
marlenablue
in
MPN Voice
2 years ago
up coming appointment
Praying he doesn’t dismiss me and hopefully will let me try
Besremi
that is sitting in my fridge! Thanks for all of the support. I am just so anxious!
Praying he doesn’t dismiss me and hopefully will let me try
Besremi
that is sitting in my fridge! Thanks for all of the support. I am just so anxious!
KLCTJC
in
MPN Voice
2 years ago
MPN's and afib
There are a few papers on the subject, but if you are on
Besremi
to control your blood counts, does the risk go down? It is so tricky getting clear answers when diagnosed with another condition when you have an MPN.
There are a few papers on the subject, but if you are on
Besremi
to control your blood counts, does the risk go down? It is so tricky getting clear answers when diagnosed with another condition when you have an MPN.
Elizka
in
MPN Voice
2 years ago
Real world experience with Besremi in ET and PV following exposure to Pegasys.
Third generation pegylated IFNα, ropeginterferon alfa-2b (ropegIFN;
Besremi
), was recommended by the European Medicine Authority (EMA) for treatment of Polycythaemia Vera (PV) following a Phase III trial (PROUD-PV / CONTINUATION-PV).
Third generation pegylated IFNα, ropeginterferon alfa-2b (ropegIFN;
Besremi
), was recommended by the European Medicine Authority (EMA) for treatment of Polycythaemia Vera (PV) following a Phase III trial (PROUD-PV / CONTINUATION-PV).
Manouche
in
MPN Voice
2 years ago
Update 7.4
We will carry on with the current plan,
Besremi
150mcg and monitor labs every 8 weeks. I am very pleased that the three more doses of
Besremi
+ a single phlebotomy brought me back down to target with no adverse effects.
We will carry on with the current plan,
Besremi
150mcg and monitor labs every 8 weeks. I am very pleased that the three more doses of
Besremi
+ a single phlebotomy brought me back down to target with no adverse effects.
hunter5582
in
MPN Voice
2 years ago
Besremi and kidney function
I’ve just started
besremi
but have been concerned about my kidneys (GFR now 45, creatinine 1.22) Anyone out there in PV world had this issue with
besremi
? I’d like to stay on
besremi
but not at the cost of damaging my kidneys. Thanks for any input!
I’ve just started
besremi
but have been concerned about my kidneys (GFR now 45, creatinine 1.22) Anyone out there in PV world had this issue with
besremi
? I’d like to stay on
besremi
but not at the cost of damaging my kidneys. Thanks for any input!
P1pp1r
in
MPN Voice
2 years ago
BMB Results Show Grade 3 MF
My doctor has taken me off
Besremi
since my blood counts, particularly my platelets dropped. Now about a month and a half off of it. I'm getting a CBC in 2 days and trying not to be scared. My platelets did start to come up right after stopping the
Besremi
(53 to 87 in 2 weeks).
My doctor has taken me off
Besremi
since my blood counts, particularly my platelets dropped. Now about a month and a half off of it. I'm getting a CBC in 2 days and trying not to be scared. My platelets did start to come up right after stopping the
Besremi
(53 to 87 in 2 weeks).
marlenablue
in
MPN Voice
2 years ago
Interesting
The research indicates that an amended dosing schedule, with higher initial dose and faster dose titration of ropeginterferon alfa-2b (marketed as
BESREMi
®), may correlate to earlier complete hematological response (CHR) in polycythemia vera (PV) in adults.
The research indicates that an amended dosing schedule, with higher initial dose and faster dose titration of ropeginterferon alfa-2b (marketed as
BESREMi
®), may correlate to earlier complete hematological response (CHR) in polycythemia vera (PV) in adults.
wateron
in
MPN Voice
2 years ago
Rux and IFN combo therapy
In the plot here from this report I've added the Ropeg (
Besremi
) results. Not necessarily comparable across different studies, including this one used PEG, but interesting. Even assuming the median start at 47%, combo got to 6% while Ropeg alone is 14% at 2 years.
In the plot here from this report I've added the Ropeg (
Besremi
) results. Not necessarily comparable across different studies, including this one used PEG, but interesting. Even assuming the median start at 47%, combo got to 6% while Ropeg alone is 14% at 2 years.
EPguy
in
MPN Voice
1 year ago
Besremi
anyone else on
besremi
and being weaned off hydroxyurea then the numbers are creeping up? Finally after nine months of
besremi
my platelets were in the normal range then climbed 600s two weeks later now 700s after another two weeks i’m so disappointed I keep crying
anyone else on
besremi
and being weaned off hydroxyurea then the numbers are creeping up? Finally after nine months of
besremi
my platelets were in the normal range then climbed 600s two weeks later now 700s after another two weeks i’m so disappointed I keep crying
Ggrana3192
in
MPN Voice
2 years ago
Two Besremi doses and the itching begins!!
Since being on
Besremi
though I have had the dreaded pins and needles/stinging/itching that so many on this board suffer from. My question is, is it my horrible numbers or the
Besremi
that is causing this? And what to do?😩 Miriam
Since being on
Besremi
though I have had the dreaded pins and needles/stinging/itching that so many on this board suffer from. My question is, is it my horrible numbers or the
Besremi
that is causing this? And what to do?😩 Miriam
Miriammusic
in
MPN Voice
2 years ago
Starting Besremi Next Week
The oncologist has prescribed me 50 mg of
Besremi
, at my request. I am 55 and did not want to do HU for years. She agreed that I am too young to start on this and should hold off if possible. I will take the first does to the infusion center next week for someone to show me how to inject it.
The oncologist has prescribed me 50 mg of
Besremi
, at my request. I am 55 and did not want to do HU for years. She agreed that I am too young to start on this and should hold off if possible. I will take the first does to the infusion center next week for someone to show me how to inject it.
MrsBerri
in
MPN Voice
2 years ago
1
...
8
9
10
...
19
Next page
10
Filter results
Clear filters
Posted in
All communities
MPN Voice
368 results
Fight MPN
2 results
Sort by
Most Relevant
Newest